Topical formulations of L-ascorbic acid dissolved in a combination of a urea agent and a non-aqueous skin-compatible solvent are provided. The formulations are storage stable for an extended period of time without significant degradation of the L-ascorbic acid in the composition, are have desirable physical properties. The topical formulations can include high concentrations of the L-ascorbic acid. The topical formulations can include cinnamic acid or derivatives thereof as a penetration enhancer and stabilizing component of ascorbic acid. Topical compositions of this disclosure find use in treating or preventing a variety of cosmetic and/or dermatological conditions as well as to reduce the appearance of chronological and/or environmentally-caused skin aging.

Described herein is a nanofibre matrix comprising 100% natural biopolymers selected from polysaccharides and/or proteins with optional functional ingredients for use as cosmetic products. More specifically, nanofibre matrix manufactured by electrospinning methods comprising a dry sheet without containing any preservatives, surfactants, solvents and crosslinkers. To use nanofibre cosmetic products, simply wet skin and then apply the nanofibre to skin. Functional ingredients may be optionally incorporated within the nanofibre matrix during electrospinning to provide different cosmetic effects. Functional ingredients offer skin benefits such as moisturizing, anti-ageing, wrinkle reduction, brightening, antioxidant and acne treatment. Functional ingredients can be essential oil where it is incorporated into nanofibre matrix to provide scent effect to cosmetic products. Functional ingredients can also be natural dye where it is incorporated in nanofibre matrix to make coloured nanofibres. Coloured nanofibres can be used for makeup products such as blush, eye shadow, eyebrow, nail polish, lipstick, contouring and hair dye product. The nanofibre matrix comprising 100% natural biopolymers with or without functional ingredients can be processed to assorted shapes or easily cut by consumers for using on different areas of skin for different purposes.

A hydrogel-fabric composite for cosmetic and therapeutic applications. This application allows the shape retaining solidified gel structure or multi gel composite of a desired hydrogel or blend of hydrogels to disperse the active solutes within the gel more evenly while maintaining activity and then resulting in a set gel shape that conforms with an underlying fabric substrate. Specifically, having the active solutes dispersed within the gel provides an even concentration of active solutes and penetrates the skin over a set amount of time due to the concentration gradient. Further, the temperature constraints of active solute ingredients while still suspending them within the hydrogel for cosmetic use allow for adequate suspension and dissolution of active ingredients throughout the final gel product. Shape retaining Hydrogels, when used with specific active solutes, will remain translucent inferring the purity of the product. Preferred hydrogels to be used in cosmetic facemasks include agar, agarose, carrageenan, carbomers, carboxymethyl cellulose, ethyl cellulose, gelatin, hydroxyethyl cellulose, hydroxypropyl cellulose, magnesium aluminum silicate (veegum), methylcellulose, poloxamers, polyvinyl alcohol, sodium alginate, tragacanth gum, and xanthan hum. Use of a specific hydrogel from this list will depend on which active ingredients are desired to be included in the final product. The process described herein allows for increased dissolution of active ingredients into the final product.

The present invention relates to non-toxic consumable compositions and formulations comprising chelator and base having synergistic effects on microbial metabolism and/or growth and/or pathogenic effectors and their use to promote and maintain health in mammals. The current invention also relates to non-toxic consumable compositions comprising more than one chelator and/or more than one base. The present invention further relates to methods for selecting said chelator and base composition and methods for detecting conditions in which selected compositions may be used. The present invention relates to the synergistic compositions and methods of their use for maintaining health, promoting health and treating diseases.

The hand sanitizer may be a hand foam sanitizer or a hand gel sanitizer. Each of the hand sanitizers includes at least one stabilizing agent, at least one skin care agent, and a volume of disinfecting micelle capsules suspended therein. Each disinfecting capsule has a polymer shell which defines a hollow core. The polymer shell includes an antimicrobial material. The antimicrobial material may have a concentration of between 0.5 wt % and 95 wt % of the polymer shell. In order to make the hand foam sanitizer, at least one foaming agent is added to produce a foam by air foaming. The hollow core of each disinfecting capsule may be filled with a material, such as at least one disinfectant, at least one fragrance, at least one supplemental skin care agent, or combinations thereof.

The instant disclosure relates to hair treatment compositions that provide brightening, shine, and luster to hair, wherein the hair treatment compositions include: (a) ascorbyl glucoside; (b) ethylenediaminetetraacetic acid, a salt thereof, or a combination thereof; (c) one or more nonionic thickening agents; and (d) water. Also disclosed are methods for using the hair treatment compositions, for example, for enhancing brightness, shine, luster of the hair.

A frozen serum and applicator thereof is disclosed, including a mold having a first half releasably engaged with a second half. When engaged, the first half and the second half form a reservoir therebetween to accept a volume of a serum. The serum is frozen within the mold to produce a frozen serum having at least one receiver molded thereon to releasable engage with an applicator configured to permit the frozen serum to be rolled. An opening is provided on the mold to permit the serum to be disposed within the reservoir.

Disclosed is a method of improving a condition or appearance of skin. The method can include applying to skin an effective amount of a topical skin composition comprising tetrahexyldecyl ascorbate, Phyllanthus emblica fruit extract, and tocopherol or tocopherol acetate.

A pharmaceutical composition or a cosmetic composition for treating hair loss, or promoting hair growth is described. The composition according to the present invention exhibits an excellent effect of treating hair loss and promoting hair growth, and can be safely used regardless of sex and age.

A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.