Disclosed are topical mucoadhesive compositions comprising hyaluronic acid or a salt thereof, choline alfoscerate, an ascorbic acid ester at a concentration ranging between 0.050% w/w and 0.0004% w/w, and at least one pharmaceutically acceptable excipient or carrier.

The present invention relates to a composition, notably a cosmetic composition, in particular for making up and/or caring for keratin materials, comprising at least retinol, di-t-butyl pentaerythrityl tetrahydroxycinnamate, an ethylenediaminedisuccinic acid salt, and at least one compound chosen from ascorbic acid or an analog thereof, and/or tocopherol or a derivative thereof.

The present specification describes an additive composition for preventing the precipitation of vitamin C in a cosmetic composition containing 15 wt % or more of vitamin C. The additive composition of the present invention comprises one or more of 3-O-ethyl ascorbic acid and caffeine as an active ingredient, and can thereby prevent precipitation of vitamin C even when a cosmetic composition is in cold storage. In addition, the additive composition according to the present invention can ameliorate the tingling irritation and stickiness that results from the inclusion of a high content of vitamin C.

Topical formulations including a combination of L-ascorbic acid, a urea agent and a chemical exfoliant dissolved in a non-aqueous skin-compatible solvent are provided. The topical formulations including a chemical exfoliant can be used as a chemical peeling solution. The formulations are storage stable for an extended period of time without significant degradation of the L-ascorbic acid or urea in the composition, are have several desirable physical properties when topically applied to skin. Topical compositions of this disclosure find use in treating or preventing a variety of cosmetic and/or dermatological conditions as well as to reduce the appearance of chronological and/or environmentally-caused skin aging. In some embodiments, the topical composition finds use as a chemical peeling solution, e.g., to facilitate shedding of the top layers of skin cells after topical administration.

The present invention relates to a composition, especially a cosmetic composition, in particular for making up and/or caring for keratin materials, comprising at least retinol, an ethylenediaminedisuccinic acid salt, at least one compound chosen from ascorbic acid or an analog thereof, and tocopherol or a derivative thereof.

Provided herein are a cosmetic composition, a health functional food composition, a pharmaceutical composition, and a quasi-drug composition that include ionone or a salt thereof as an active ingredient and have an effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, or alleviating skin photoaging. The ionone or the salt thereof has an activity of enhancing skin moisture content, reducing skin moisture evaporation, increasing procollagen secretion, promoting collagen biosynthesis, suppressing collagen fiber damage, suppressing collagen fiber decomposition, inhibiting erythema, and suppressing the thickening of a skin epidermis layer, and thus may be usefully used as a material of functional cosmetics, health functional foods, pharmaceuticals, quasi-drugs, or the like that provide an effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, and/or alleviating skin photoaging.

The present invention concerns a substrate-based product comprising a water-insoluble substrate, at least one chemical exfoliator, and at least one skin binding agent, its method of preparation and its cosmetic uses.

A method for topically treating skin is disclosed. The method can include applying to skin a composition that includes tetrahexyldecyl ascorbate, Morus alba fruit extract, Acmella oleracea extract, and retinol, wherein topical application of the composition treats the skin.

A substantially non-aqueous, stable, lyophilic dermatological concentrate comprised of: (i) a hydroxy acid, preferably selected from the group consisting of (a) azelaic acid at a concentration of at least about 20% or (b), ascorbic acid, at a concentration of up to about 30%; (ii) glycerin; and (ii) hyaluronan and/or an alginate, and derivatives thereof.

Moisturizer compositions include about 1 to about 5 wt % niacinamide, about 0.5 to about 2 wt % pantothenic acid, about 0.5 to about 2 wt % pyridoxine, about 0.05 to about 1 wt % of a skin barrier enhancer, about 1 to about 10 wt % of a humectant, about 1 to about 10 wt % citric acid, about 0.1 to about 0.5 wt % an ascorbic acid salt or an ascorbic acid derivative, about 0.01 to about 0.2 wt % of a non-naturally occurring preservative, about 0.5 to about 2 wt % of a natural preservative and balance of a water:glycerin mixture, where the water:glycerin mixture has at least about 50 wt % water.