Compositions and methods are disclosed for imparting super-hydrophobic properties to cosmetics, in particular mascaras. The compositions comprise a hydrophobic film former in combination with hydrophobically-modified iron oxide pigments and/or carbon black.

Compositions and methods are disclosed for imparting super-hydrophobic properties to cosmetics, in particular mascaras. The compositions comprise a hydrophobic film former in combination with hydrophobically-modified iron oxide pigments and/or carbon black.

The present invention discloses a hydrophobic and lipophobic cosmetic pigment powder, including pigment powder and a skin-fitting treatment agent. The skin-fitting treatment agent can perform surface compounding treatment on the pigment powder and includes fluorine-containing silane and hydrogenated lecithin. The hydrophobic and lipophobic cosmetic pigment powder has excellent hydrophobic and lipophobic properties, has excellent pickable property and skin-fitting property, and makes skin elastic, soft and smooth. The perfluorinated silane treatment agent in the present invention has a carbon number less than or equal to 8, is safe, skin-friendly and nontoxic, and can achieve effects of nourishing skin and easily removing makeup due to addition of pure plant ingredients with excellent skin affinity.

The present invention discloses a hydrophobic and lipophobic cosmetic pigment powder, including pigment powder and a skin-fitting treatment agent. The skin-fitting treatment agent can perform surface compounding treatment on the pigment powder and includes fluorine-containing silane and hydrogenated lecithin. The hydrophobic and lipophobic cosmetic pigment powder has excellent hydrophobic and lipophobic properties, has excellent pickable property and skin-fitting property, and makes skin elastic, soft and smooth. The perfluorinated silane treatment agent in the present invention has a carbon number less than or equal to 8, is safe, skin-friendly and nontoxic, and can achieve effects of nourishing skin and easily removing makeup due to addition of pure plant ingredients with excellent skin affinity.

Methods and compounds are disclosed for wound healing by modulating autophagy. A formulation for modulating autophagy comprises a first modulating compound (FAM) selected from compounds having the general structure (I):

##STR00001## wherein: L represents a linker selected from C?C, (a tolan), CH?CH (a stilbene, preferably trans); or CR.sub.a?CR.sub.b a stilbene derivative; where R.sub.a and R.sub.b are independently H or phenyl optionally substituted with (R.sup.3).sub.p or (R.sup.4).sub.q;

R.sup.1 to R.sup.4 are independent substituents at any available position of the phenyl rings, preferably at 3, 3, 4, 4, and/or 5, 5; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be ?1. Each R.sup.1 to R.sup.2 is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides. The formulation may also include an auxiliary autophagy modulating compound (AAM) as described herein. The formulation may include a hydrogel formed by the compounds themselves or otherwise and may include salts and/or complexes.

Methods and compounds are disclosed for wound healing by modulating autophagy. A formulation for modulating autophagy comprises a first modulating compound (FAM) selected from compounds having the general structure (I):

##STR00001## wherein: L represents a linker selected from C?C, (a tolan), CH?CH (a stilbene, preferably trans); or CR.sub.a?CR.sub.b a stilbene derivative; where R.sub.a and R.sub.b are independently H or phenyl optionally substituted with (R.sup.3).sub.p or (R.sup.4).sub.q;

R.sup.1 to R.sup.4 are independent substituents at any available position of the phenyl rings, preferably at 3, 3, 4, 4, and/or 5, 5; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be ?1. Each R.sup.1 to R.sup.2 is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides. The formulation may also include an auxiliary autophagy modulating compound (AAM) as described herein. The formulation may include a hydrogel formed by the compounds themselves or otherwise and may include salts and/or complexes.

This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of using and of making these compositions.

This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of using and of making these compositions.

Pharmaceutical carriers which provide an environment of physical and chemical stability comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound of structure I, one or more antioxidants, one or more chelators and a vehicle base comprising water and one or more pharmaceutically acceptable non-aqueous solvents, one or more absorption enhancers, one or more gelling agents and one or more pH buffering agents are described.

##STR00001##

Provided are compositions, preferably azeotrope or azeotrope-like compositions including 1,1,1,4,4,4-hexafluoro-2-butene and chlorotrifluoropropene, particularly 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd), and uses thereof of the compositions. The composition may be a heat transfer composition. The composition may be a blowing agent composition. The composition may be a solvent composition. The composition may be a sprayable composition.