A toothpaste product that is laced with, or infused with, a sedative such as the active ingredients in cannabis. The act of brushing one's teeth using the present invention transfers the sedative into the bloodstream through contact with the gums, leading to a more restful sleep.

This invention relates generally to cellulose nanocrystal-based emulsions that can serve as a spray adjuvant for improved agrochemical application efficiency. More particularly, the cellulose nanocrystal-based emulsions are nanocellulose-stabilized Pickering emulsions having a semi-liquid formulation of colloidal cellulose nanocrystals and biopolymers that can substitute currently used surfactants and drift reducing agents in agrochemicals. The cellulose nanocrystal-based emulsions are suitable with both water soluble and oil soluble active ingredient chemistries, and the shear characteristics of the emulsions make them suitable for oil in water-based spray applications. Droplet size distribution can be tuned by changing the ingredient concentrations, thus helping control particle drift. Moreover, a stable cross-linked network formation facilitates the entrapment and encapsulation of volatile agrochemical chemistries, thus preventing their volatilization and reducing vapor drift.

The present invention provides a preparation for attaching to teeth or tooth peripheries. The preparation for attaching to teeth or tooth peripheries of the present invention can give high adhesive force to the desired site despite interproximal space or curves of teeth. It is easy to hand while controlling drug release.

The present invention relates to an aqueous composition comprising (i) at least hydrogel beads comprising 2 gelling agents chosen from (hetero)polysaccharides, (ii) at least one foaming surfactant, and (iii) at least anacrylic copolymer of acrylic acid and C10-C30 alkyl acrylate. The present invention further relates to the use of said composition as a cleansing scrub composition of the skin.

The present invention relates to capsules comprising a peptide, lecithin, alginate, and divalent metal cation, compositions comprising said capsules, use thereof in cosmetic treatments, as well as methods of obtaining said capsules.

The present description relates to a skin ointment or topical composition for skin rejuvenation and/or repair. The composition generally comprises: a biocompatible mixture of probiotics (e.g., probiotic yeast and/or bacteria); admixed with one or more of: exfoliating agents, mud and/or clay, blood circulation promoting agent, and nutrients. Methods, uses and kits relating to same are also described.

The invention relates to a disintegrating oral tablet suitable for active pharmaceutical ingredients comprising a population of particles and at least one flavor ingredient, the population of particles comprising directly compressible (DC) and non-directly compressible (non-DC) sugar alcohol particles, the non-DC particles providing the tablet with a plurality of discrete non-DC areas, and

the non-DC areas resulting in a burst of the at least one flavor ingredient upon mastication of the tablet.

A cosmetic gel sheet suitable for a cosmetic field or a medical field is provided.

The cosmetic gel sheet of the present invention contains carboxy group-containing water-soluble polymer, polyalcohol, and acid as essential constituent components. Carboxy group-containing polysaccharide can be suitably used as the carboxy group-containing water-soluble polymer. Water content in the gel sheet is 30% by weight, but it is more preferable if the water content is 10% by weight or less. In the cosmetic gel sheet of the present invention, the gel sheet can be manufactured by drying an aqueous solution containing carboxy group-containing water-soluble polymer, polyalcohol, and acid as essential components. Wherein, it is desirable that content of the acid in the aqueous solution is adjusted to a value appropriate for setting pH of the aqueous solution to 2.0-4.0.

A method of manufacturing a series of capsules (1A) comprising a core (3), and a gelled envelope (5) completely encapsulating the core and comprising at least two external phases (5A, 5B), wherein the gelled envelope has a external surface comprising at least two distinct portions (7A, 7B) formed respectively by the two external phases, and comprising the following steps: conveying a first flow (F1) that is intended to form the core, and a second flow (F2) of at least the two external phases that are intended to form the gelled envelope, wherein each external phase contains a liquid polyelectrolyte that is able to gel, at least one of the two external phases comprising a coloring agent, while the second flow surrounds the first flux about an axis (D2); successive formation of a plurality of liquid bodies (57) comprising a drop (107), and a film coating (109) coating the drop and having the two external phases, wherein the film has on its external surface at least two portions (109A, 109B) formed by the two external phases; and immersing each liquid body in a gelling solution (100) adapted to react with the polyelectrolyte of each of the two external phases, and recovering of the plurality of capsules. Series of capsules, cosmetic composition containing the capsules and cosmetic treatment using the composition.

A system and method for high-speed, low-power cryogenic computing are presented, comprising ultrafast energy-efficient RSFQ superconducting computing circuits, and hybrid magnetic/superconducting memory arrays and interface circuits, operating together in the same cryogenic environment. An arithmetic logic unit and register file with an ultrafast asynchronous wave-pipelined datapath is also provided. The superconducting circuits may comprise inductive elements fabricated using both a high-inductance layer and a low-inductance layer. The memory cells may comprise superconducting tunnel junctions that incorporate magnetic layers. Alternatively, the memory cells may comprise superconducting spin transfer magnetic devices (such as orthogonal spin transfer and spin-Hall effect devices). Together, these technologies may enable the production of an advanced superconducting computer that operates at clock speeds up to 100 GHz.