A macromolecular hyaluronic acid is used as a raw material, and is subjected to production processes such as hyaluronidase hydrolysis, heating and inactivation, activated carbon filtration, and spray and dry to obtain an ultra-low molecular weight hyaluronic acid product having an average molecular weight of less than 1200 Da. The product is a mixture of hyaluronic acid disaccharide to dodecaose. The content of hyaluronic acid disaccharide is 5-40%. The content of hyaluronic acid tetrasaccharide is 40-70%. The content of hyaluronic acid hexasaccharide is 10-30%. The content of hyaluronic acid octasaccharide is 1-15%. The content of hyaluronic acid decaose is 1-10%. The content of that higher than hyaluronic acid decaose is less than 6%. Compared with other available low molecular hyaluronic acid, the product has a more significant permeation, moisturizing, and repair promotion capability, and can be widely used in fields of medical products, health care products, cosmetics and the like.

Improved dermal filler formulation comprising a hyaluronic acid and a botulinum toxin.

Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.

A method for preparing a cosmetic component is provided which includes applying a layer of a dry cosmetic ingredient between a pair of fibrous sheets obtained by electrospinning one or more polymeric materials at least one of which is capable of cold flow under pressure. Sufficient pressure is then applied to the layers of fibrous sheets to cause cold flow of at least some of the polymeric material such that at least parts of the fibrous sheets bond with each other and entrap the cosmetic ingredient in position between them and prevent it from migrating between the sheets during further processing or handling.

Embodiments of the present disclosure may include a skincare composition comprising an antimicrobial component, an antiaging component and a moisturizing component comprising at least one alpha-hydroxy acid. A treatment method for improving skin may include administering to an area in need thereof a composition comprising an effective amount of an antimicrobial component, an antiaging component and a moisturizing component comprising at least one alpha-hydroxy acid.

The invention relates to a personal care product for alleviating skin dryness, includes facial skin dryness, breast skin dryness and vulval dryness and for restoring vaginal flora, acidic pH in the vagina, and vaginal health. Embodiments of the personal care product include a formulation including at least about 83 wt. % plant-based glycerides; from about 0.05 wt. % to about 0.15 wt. % sodium hyaluronate; and from about 0.01 wt. % to about 1.5 wt. % sea buckthorn powder. Another embodiment includes a personal care product including at least 55 wt. % plant-based glycerides and from about 20 wt. % to about 42 wt. % sucrose. The personal care product may also include shea olein. The person care product is substantially free of added water, alcohol, synthetic chemical, anti-microbial agent, and synthetic hormone.

The invention relates to a composition comprising at least hyaluronic acid and at least one polyol and/or carboxymethyl cellulose (CMC).

The invention also relates to the use of at least one polyol and/or carboxymethyl cellulose to stabilize hyaluronic acid in a composition.

The method to produce a packaged cosmetic product comprises a step of feeding a support film along a feed path, a step of forming a membrane substrate, and a step of packaging the membrane substrate. The method can be implemented by means of a suitable apparatus, which comprises a station for feeding the support film, a station for forming the membrane substrate, and a packaging unit, which are disposed in succession along the feed path of the support film.

A cosmetic composition includes one or more solvents and one or more rejuvenation cosmetic components. The one or more solvents include dimethyl sulfoxide and/or dimethyl sulfone. The one or more rejuvenation cosmetic components, include botulinum toxin, hyaluronic acid, and/or exosomes. A delivery system includes a transdermal patch including the cosmetic composition. The cosmetic composition is topically applied to the skin of a patient.

Disclosed is a method of treating a fine line or wrinkle in a person's skin, the method comprising topically applying to the fine line or wrinkle a composition comprising an effective amount of Commiphora mukul resin or an extract thereof that includes oleo gum resin, glycerin, water, and hyaluronic acid or a salt form thereof, wherein topical application of the composition to the fine line or wrinkle reduces the appearance of the fine line or wrinkle.