A61K8/736

Dual-function starch-based composite nanoparticles as well as preparation method and application thereof

The present application discloses dual-function starch-based composite nanoparticles as well as a preparation method and application thereof. The preparation method comprises: hydrolyzing starch to form linear dextrin, grading the linear dextrin by using an alcohol-alcohol gradient precipitation method to obtain linear dextrin having homogeneous molecular weight distribution; oxidizing the linear dextrin by adopting an oxidation system to obtain oxidized dextrin; carrying out complex reaction on the oxidized dextrin and curcumin to form an oxidized dextrin-curcumin complex; and forming an oxidized dextrin-curcumin/chitosan hydrochloride composite nanoparticles from the oxidized dextrin-curcumin complex and chitosan hydrochloride. The aqueous phase solution of the dual-function starch-based composite nanoparticles containing gel polysaccharide is uniformly mixed with primary emulsion, calcium ion induction is carried out on the obtained double emulsion to obtain double-emulsion gel.

Skin care composition

A skin care composition includes a carrier substance and a proportion of lactic acid bacteria and/or their metabolic products, wherein the metabolic products are included in the skin care composition in a form of a ferment obtained during a cultivation of the lactic acid bacteria. The skin care composition additionally contains chitosan or a suitable chitosan derivative.

COMPOSITE MICROCAPSULES

Described herein is a composite microcapsule slurry including at least one microcapsule having an oil-based core including a hydrophobic material, preferably a perfume, and a composite shell including a first material and a second material. The first material and the second material are different, the first material is a coacervate, the second material is a polymeric material, and the weight ratio in the slurry between the first material and the second material is between 50:50 and 99.9:0.1.

CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS

A biodegradable core-shell microcapsule composition with controlled release of an active material is provided, wherein the shell of the microcapsule is composed of a biopolymer.

Topical compositions containing low molecular weight chitosan derivatives

Disclosed are topical composition for delivery of an active agent to keratinous tissue, comprising a low molecular weight chitosan that is covalently modified chitosan with octane sulfonic acid which are attached to the chitosan via sulfonamide linkages (OsC), an effective amount of an active agent, and a carrier, and wherein the chitosan has a molecular weight of about 50 kD to about 150 kD. Also disclosed are methods of making the compositions and methods of using the compositions that entail topical application.

Topical Skin Treatment
20230270661 · 2023-08-31 ·

A topical skin treatment for the mitigation of various skin irritations and abnormal skin conditions, the composition and method for making the topical skin treatment providing a mixture of tea extracts from the snow mushroom, Reishi mushrooms, and other various organic ingredients in a range of constituent amounts to form a homogeneous liquid compound solution applied to the skin in liquid or aerosol form.

CONSUMER PRODUCT COMPRISING BIODEGRADABLE DELIVERY PARTICLES

A consumer product composition including a biodegradable delivery particle having a benefit agent containing core and a shell.

SOLID DISPERSIONS AND PARTICLES AND METHODS FOR CONTROLLED-RELEASE OF LIPID-SOLUBLE OR DISPESIBLE ACTIVES
20230263754 · 2023-08-24 ·

The invention provides a particle comprising a lipid core and surface-decorated (nano)particles of at least one stabilizing material, for delivery of active agents.

Hydrogen sulfide releasing polymer compounds

The invention provides a hydrogen sulfide releasing polymer compound having a polysaccharide backbone, wherein the compound has at least two substructures, and wherein said substructures are capable of releasing hydrogen sulfide by thiol activation as well as uses thereof. Additionally, a method of treatment and prevention of a skin condition, an ocular disease or osteoarthritis is provided.

Self-standing cosmetic sheet

The present invention relates to a cosmetic process which applies onto the skin a self-standing cosmetic sheet for the skin, comprising: at least one biocompatible and/or biodegradable hydrophobic polymer layer wherein the self-standing cosmetic sheet has a thickness of from 10 to 1000 nm, preferably from 30 to 500 nm, and more preferably from 50 to 300 nm. The cosmetic sheet according to the present invention may comprise at least one cosmetic active ingredient. The cosmetic sheet used in the present invention is very thin and not easily perceived on the skin; can be prepared with a variety of materials such as a biocompatible and/or biodegradable material; and can adhere well onto the skin without any adhesive layer so that it is less irritable or no irritable to the skin.