The disclosure relates to methods of treating curly hair in connection with a bleaching process. The methods can improve and/or restore hair integrity, curl definition, and/or durability; prevent or reduce curl elongation; improve frizz and/or volume control; and/or prevent or reduce damage to the hair related to the bleaching process. The methods comprise applying a composition to the hair before and/or after the hair is treated with a bleaching composition, where the composition comprises (a) at least one carboxylic acid or salt thereof; (b) at least one cyclodextrin or derivative thereof; (c) at least one polysaccharide; (d) at least one polyol; and (e) water.

The disclosure relates to compositions comprising (a) at least one carboxylic acid or salt thereof; (b) at least one cyclodextrin or derivative thereof; (c) at least one polysaccharide thickening agent; (d) at least one polyol; and (e) optionally water. The pH of the composition is less than 7. The compositions can be used for providing lasting curl definition and/or frizz and/or volume control to hair, even in high humidity. The disclosure also relates to methods of making and using the compositions, and kits containing the compositions.

Disclosed herein are compositions comprising complexes of cyclodextrins and lipid-modified stem cell proteins. Also disclosed are topical compositions the complexes. Methods of using the compositions for the therapeutic purposes are also disclosed as well as methods of producing the compositions.

A composition includes a crosslinked polysiloxane elastomer with 2 or more carbon-oxygen-silicon linkages between a polysaccharide component and polysiloxane component, where the polysaccharide component is other than a cellulose or starch component.

The present disclosure discloses a preparation method of ginseng composition with high ginsenoside bioavailability. The composition is composed of ginseng powder of 250 meshes or more and ?-cyclodextrin, and the mass ratio of the ginseng powder to the ?-cyclodextrin is 1:0.05. Results show that when ?-cyclodextrin is used as a solid dispersant and added to the 1000-mesh ginseng powder at a mass ratio of 5%, the total dissolution amount is maximum; and furthermore, animal experiments (SD rats) show that the area under the plasma drug concentration-time curve (AUC.sub.0-48 h) after 48 h of ginseng powder ingestion is maximum, indicating that in-vivo bioavailability of the ginseng powder is the highest. The method of this application can effectively inhibit the aggregation of the ultra-finely pulverized 1000-mesh ginseng powder by adding the ?-cyclodextrin, thus significantly improving the total dissolution amount of ginsenoside.

The present invention relates to a composition and method for stabilisation of compounds including retinoids using the synergistic effects of beta-carotene and sodium polyaspartate.

Methods and compounds are disclosed for wound healing by modulating autophagy. A formulation for modulating autophagy comprises a first modulating compound (FAM) selected from compounds having the general structure (I): ##STR00001## wherein: L represents a linker selected from CC, (a tolan), CHCH (a stilbene, preferably trans); or CR.sub.aCR.sub.b a stilbene derivative; where R.sub.a and R.sub.b are independently H or phenyl optionally substituted with (R.sup.3).sub.p or (R.sup.4).sub.q; R.sup.1 to R.sup.4 are independent substituents at any available position of the phenyl rings, preferably at 3, 3, 4, 4, and/or 5, 5; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be 1. Each R.sup.1 to R.sup.2 is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides. The formulation may also include an auxiliary autophagy modulating compound (AAM) as described herein. The formulation may include a hydrogel formed by the compounds themselves or otherwise and may include salts and/or complexes.

A perfume composition for improved release from a cyclodextrin complex, wherein the perfume composition includes 10% or more, by weight of the perfume, of one or more perfume raw materials having: a cyclodextrin complex stability constant of about 3.0 or less, a C log P of about 2.5 or less; and a weight average molecular weight of about 200 Daltons or less.

Methods of making personal care compositions including microcapsules and methods of enhancing the efficacy of the microcapsules in said personal care compositions.

Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.