The present disclosure relates to a supramolecular preparation of retinol and derivatives thereof and a preparation method therefor, wherein the supramolecular preparation consists of following components in percentage by mass: 3.00-25.0% of retinol and derivatives thereof, 36.5-91.0% of hydroxypropyl γ-cyclodextrin, 4.00-32.0% of hydroxypropyl methylcellulose stearoxy ether, and 2.00-8.0% of PEG/PPG/polybutylene glycol-8/5/3 glycerin, wherein the mass ratio of the PEG/PPG/polybutylene glycol-8/5/3 glycerin to the hydroxypropyl methylcellulose stearoxy ether is 1:2-4. The supramolecular preparation of retinol and derivatives thereof obtained in the present disclosure has the advantages such as good stability, high solubility, low irritation, and good anti-wrinkle effect.

A method for preparing Ganoderma lucidum extract using an eco-friendly extraction technique is disclosed. A Ganoderma lucidum extract prepared thereby and a cosmetic composition containing the extract, and their uses are disclosed. The extraction technique use an aqueous cyclodextrin solution alone or in combination with ultrasonic extraction to afford a Ganoderma lucidum extract containing a high concentration of the effective ingredient triterpenoid.

A composition containing one or more materials selected from the group consisting of fatty acids, proteins, peptides, amino acids, vitamins, minerals, alcohols, sweeteners, acidulants, antioxidants, thickening stabilizer, and surfactants, and a flavonoid-cyclodextrin inclusion compound, wherein the inclusion compound contains an inclusion compound obtained by treating a flavonoid having a rhamnoside structure with an enzyme having rhamnosidase activity in the presence of a cyclodextrin. According to the present invention, the bitterness and the changes in color tones originated from flavonoids can be inhibited, and foodstuff or the like having an unpleasant taste can be improved, so that the present invention can be suitably utilized in fields such as medicaments, foodstuff, health foods, foods for specified health use, and cosmetics.

Cosmetic and dietary supplement compositions containing silymarin and sulfoalkyl ether cyclodextrin, particularly sulfobutyl ether cyclodextrin, are described. The compositions and methods are useful in reducing appearance of facial redness in rosacea-prone skin, rejuvenating skin, preventing skin aging, inhibiting oxidative stress in epidermal and dermal cells, increasing collagen production, reducing the likelihood of skin cancer, treating or reducing liver damage from a toxin, or treating a liver disease.

Disclosed are an inclusion compound containing a non-psychoactive cannabinoid, and a method for preparation thereof. The inclusion compound is prepared by means of the following method: a cannabis extract is subjected to, in sequence, dissolving in organic solvent, incorporation of inclusion agent, analysis and removal of impurities in water-organic solvent, and vacuum drying and precipitation, and thus obtained. In the inclusion compound, psychoactive ingredients such as tetrahydrocannabidiol (THC) and Δ9-tetrahydrocannabinol (THCV) may be completely removed, effectively enriching the non-psychoactive ingredients such as cannabidiol (CBD), cannabigerol (CBG), cannabichromene (CBC), and so on with a total content of greater than 50%. The processing technique of the preparation method is simple to perform, and is conducive to commercialization.

Compositions comprising 5-cholesten-3,25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.

A method for producing an inositol derivative includes a step of reacting inositol and dextrin in the presence of cyclodextrin glucanotransferase to generate an inositol derivative in which a sugar is bonded to the inositol, and to obtain a solution containing the inositol derivative and the cyclodextrin glucanotransferase; and a step of removing the cyclodextrin glucanotransferase in the solution using an ultrafiltration membrane, in which a deactivation treatment of the cyclodextrin glucanotransferase in the solution is not performed.

Disclosed are a method for preparing exosomes from bovine placenta, lyophilized powder of the exosomes, as well as a composition containing exosomes from animal placenta and a preparation method and use thereof in anti-wrinkle on skin.

Suggested are surfactant compositions comprising: One or more alpha-sulfofatty acid disalts (A) of general formula (I), RICH (SO3M1) COOM2 (I), wherein the radical R 1 denotes a linear or branched alkyl or alkenyl radical having 6 to 18 C atoms and the radicals M 1 and M 2-independently of one another-are selected from the group H, Li, Na, K, Ca/2, Mg/2, Ammonium and alkanolamines and one or more polysaccharides (B) selected from the group consisting of dextrin and its derivatives, starch and its derivatives, cellulose and its derivatives, preferably one or more dextrins (B) of the general formula (II), (II) in which n is an integer between 3 and 200.

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A topical composition treating dandruff and seborrheic dermatitis of a scalp, by restoring architectonics to the scalp, eliminating fungal infection from the scalp, regulating metabolism of the scalp, regulating production and release of sebum from the scalp, and detoxifying the scalp. The topical composition includes an anti-fungal and scalp metabolism regulator, a delivery system, a detoxifying and impurity eliminator, and a fragrance. The anti-fungal and scalp metabolism regulator includes zinc pyrithione, climbazole, melatonin, multi-functional polyethylene glycol, and hydroxypropyl-ß-cyclodextrin. The delivery system includes first and second solutions. The first solution includes dimethylsulfoxide and hydroxypropyl-ß-cyclodextrin. The second solution includes distilled water, sodium chloride, potassium chloride, calcium chloride, sodium bicarbonate, imidazolidinyl urea, and multi-functional polyethylene glycol. The detoxifying and impurity eliminator includes preservatives, a pathogenic microorganism and exo- and endotoxins eliminator, and multi-functional polyethylene glycol. The preservatives include sodium benzoate and potassium sorbate. The pathogenic microorganism and exo- and endotoxins eliminator includes white activated charcoal powder.