A61K8/738

COMPOSITIONS COMPRISING 5-CHOLESTEN-3, 25-DIOL, 3-SULFATE (25HC3S) OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AT LEAST ONE CYCLIC OLIGOSACCHARIDE

Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.

INJECTABLE PHENOL FORMULATIONS AND METHODS OF THEIR USE

Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.

INJECTABLE PHENOL FORMULATIONS AND METHODS OF THEIR USE

Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.

COMPOSITION COMPRISING BENZOIC ACID AMIDE COMPOUND AND CYCLODEXTRIN SOLUBILIZING AGENT

The present specification relates to a composition for external application to skin with improved solubility and feeling during use, comprising a benzoic acid amide compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solute that is a solvate thereof, and a first cyclodextrin solubilizing agent.

ANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERS
20210137800 · 2021-05-13 ·

Anhydrous solid composition comprising an isethionic acid derivative, a glutamic acid derivative, an amphoteric surfactant and fillers The subject of the present invention is a composition, preferably a cosmetic composition, in anhydrous solid form, comprising at least one anionic surfactant chosen from isethionic acid derivatives and salts thereof, at least one anionic surfactant chosen from glutamic acid derivatives and salts thereof, at least one amphoteric surfactant, and at least 20% by weight of fillers, relative to the total weight. The composition in accordance with the invention is advantageously in the form of granules, the particle size of which is homogeneous. It readily disaggregates or disintegrates, it is easy to apply to keratin materials, and it allows rapid foam initiation, when the composition is applied to said keratin materials, and also good foam quality.

MANGIFERIN AS A PROTECTIVE AGENT AGAINST MITOCHONDRIAL DNA DAMAGE AND SKIN-CARE COMPOSITIONS COMPRISING SAME
20210106601 · 2021-04-15 ·

The invention relates to compounds that provide protective effects against mitochondrial DNA damage. In particular, it relates to mangiferin, ideally in the form of a naturally-occurring mangiferin extract, and to mangiferin-containing compositions and their use as protective agents against mitochondrial DNA damage. Aspects of the invention relate to an additive for a skin care composition, wherein the additive comprises a complex of mangiferin with β-cyclodextrin or a β-cyclodextrin derivative. The invention also relates to skin care compositions comprising the mangiferin complexes, as well as to methods of their preparation. In embodiments, the additive can be used in a sunscreen formulation to protect against UV-induced mtDNA damage.

EMULSIFYING COMPOSITION FOR COSMETIC USE FOR PRODUCING AN O/W PICKERING EMULSION AND PROCESS FOR PRODUCING THIS EMULSION

The application relates to an emulsifying composition, in particular for cosmetic use, allowing an oil-in-water emulsion (O/W) to be obtained, the emulsion comprising at least one cyclodextrin and at least one O/W emulsifier of natural origin with a hydrophilic-lipophilic balance value (HLB) of more than 8. The O/W emulsifier of natural origin can be selected from alkyl polyglucosides, mixtures of at least one alkyl polyglucoside and at least one fatty alcohol, and non-ethoxylated polyol fatty esters. The application also relates to a composition of the Pickering emulsion type, in particular for cosmetic use, containing the emulsifying composition according to the invention, and to the process for preparing such a composition of the O/W Pickering emulsion type, in particular at low temperatures.

Aerosol compositions

A personal aerosol composition including a solvent, a cyclodextrin perfume complex, and a propellant, where the cyclodextrin perfume complex includes 10% or more perfume raw materials, by weight of the perfume, having: a cyclodextrin complex stability constant of about 3.0 or less, a C log P of about 2.5 or less; and a weight average molecular weight of about 200 Daltons or less.

Fragrance materials

The present application relates to perfume raw materials, perfumes, perfume delivery systems and consumer products comprising such perfume raw materials, perfumes and/or such perfume delivery systems, as well as processes for making and using such perfume raw materials, perfume delivery systems and consumer products. The perfumes disclosed herein expand the perfume communities' options.

Compositions and/or Articles Comprising Cyclodextrin Complexing Material

Personal care products are provided. An exemplary personal care product includes a composition that is applied to the body or clothing, or an article applied against the body; a plurality of particles associated with the composition or a component of the article, the plurality of particles, at least some of the plurality of particles comprising a cyclodextrin complexing material and a first fragrance material, wherein the percent of the first fragrance material that is complexed with the cyclodextrin is greater than about 90%, so that the perceptibility of the first fragrance is minimized prior to its release; and a second fragrance material that is not complexed with the cyclodextrin and that is different from the first fragrance material, wherein the composition or article does not contain an antiperspirant active.