Improved formulations for topical treatment that ensure at least localized transdermal or systemic delivery of an active agent through skin, nails or hair follicles are disclosed.

Cosmetic and dermatological compositions, including color changing compositions, are provided which typically include a plurality of synthetic particles having a size in the micrometer or nanometer range. Each synthetic particle typically includes one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45; the aggregates having a size larger than about 100 nm and the composition being biodegradable and biocompatible.

Cosmetic and dermatological compositions, including color changing compositions, are provided which typically include a plurality of synthetic particles having a size in the micrometer or nanometer range. Each synthetic particle typically includes one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45; the aggregates having a size larger than about 100 nm and the composition being biodegradable and biocompatible.

The present invention is directed to a cosmetic composition precursor that is rapidly hydratable and conducive to creating a personalized end-product. This invention thus relates to a cosmetic composition precursor having fatty acid, inorganic base, and high HLB surfactants and methods of using said precursors in creating the end-product. The invention also relates to end-use compositions made from the hydratable cosmetic composition precursor of the invention.

A toothpaste composition includes a structurant and a thickener, wherein the toothpaste composition has a predetermined viscosity and phase angle by using the structurant instead of reducing the content of a thickener, and thereby has an improved release property during use while maintaining a shape retention property of the toothpaste, and has an improved feeling of refreshment, flavor releasing power, cleaning power, and stain removal power. Further, provided is a toothpaste composition including a chelating agent containing phosphate and silica, wherein the chelating agent is supersaturated to precipitate phosphate to provide strong cleaning power, a whitening effect, a stain removal effect, and a crunchy sensation. Further, provided is a toothpaste composition including a peroxide, a thickener, and a spreading agent, wherein the peroxide and the thickener are separated from each other, providing excellent sense of use, stability, and a whitening effect in an anhydrous state.

A toothpaste composition includes a structurant and a thickener, wherein the toothpaste composition has a predetermined viscosity and phase angle by using the structurant instead of reducing the content of a thickener, and thereby has an improved release property during use while maintaining a shape retention property of the toothpaste, and has an improved feeling of refreshment, flavor releasing power, cleaning power, and stain removal power. Further, provided is a toothpaste composition including a chelating agent containing phosphate and silica, wherein the chelating agent is supersaturated to precipitate phosphate to provide strong cleaning power, a whitening effect, a stain removal effect, and a crunchy sensation. Further, provided is a toothpaste composition including a peroxide, a thickener, and a spreading agent, wherein the peroxide and the thickener are separated from each other, providing excellent sense of use, stability, and a whitening effect in an anhydrous state.

The present invention is in the field of personal care compositions, in particular compositions comprising antiperspirant actives. The present invention more particularly relates to compositions which do not contain the conventional and well established metal based actives, yet exhibit similar efficacy. This is achieved through use of a combination of a film forming polymer, a specific solvent and a plasticizer.

Dental whitening compositions, kits and systems exhibiting stability in viscosity and hydrogen peroxide concentration for an extended shelf life without refrigeration or other special storage conditions are provided herein. The composition may be in gel form and comprise a hydrogen peroxide or a hydrogen peroxide precursor, and a thickening agent comprising a vinylpyrrolidone polymer or copolymer. In some aspects, a kit may be provided comprising a two-part dental whitening system, wherein one part comprises a whitening agent, and a separate part comprises a strong base.

To provide a beauty care sheet that can be realized much more easily than conventional methods in terms of a device and an effective manner for the purpose of filling groove portions formed into fine wrinkles, sagging wrinkles and the like of the skin and recovering youthful swelling of the skin. A microneedle array for skin application having a water-soluble polymer as a base and hydroxyapatite particles dispersed in the base, a beauty sheet intended to care for a groove portion of the skin, including the microneedle array for skin application, and a beauty sheet intended to care for wrinkles between eyebrows, wrinkles of nasolabial folds, or an intermammary groove, including the microneedle array for skin application. The particle size of the hydroxyapatite particles is preferably 5 μm or less.

To provide a beauty care sheet that can be realized much more easily than conventional methods in terms of a device and an effective manner for the purpose of filling groove portions formed into fine wrinkles, sagging wrinkles and the like of the skin and recovering youthful swelling of the skin. A microneedle array for skin application having a water-soluble polymer as a base and hydroxyapatite particles dispersed in the base, a beauty sheet intended to care for a groove portion of the skin, including the microneedle array for skin application, and a beauty sheet intended to care for wrinkles between eyebrows, wrinkles of nasolabial folds, or an intermammary groove, including the microneedle array for skin application. The particle size of the hydroxyapatite particles is preferably 5 μm or less.