A preparation method and an application of sea cucumber protein peptides are disclosed. The disclosure develops a preparation method of sea cucumber protein peptides with simple operation and excellent product quality by optimizing raw materials and enzymolysis extraction process of sea cucumber protein peptides. On the one hand, the problem that the deodorization and decolorization effect of the sea cucumber peptide hydrolysate of the prior art is not obvious is solved. On the other hand, the obtained sea cucumber protein peptides can be processed into nutritional supplements and used as raw materials for preparing health care products or cosmetics for enhancing immunity, relieving physical fatigue, resisting oxidation and aging, which has good development and utilization potential.

The invention describes methods and agents for improving cosmetic appearance, for promoting, improving or restoring health of cells and tissues, preferably skin, and more preferably, for restoring aged or damaged skin to a healthy appearance. In some embodiments, the invention relates to compositions of cells, eggs, cell extracts, egg extracts, and extract components such as purified nucleic acids, polypeptides, lipids, carbohydrates or other natural products.

Pro-toothpaste compositions formulated to receive a volume of allergen solution to provide toothpastes that exhibit efficacy for oral mucosal immunotherapy (OMIT) and acceptable consumer and product stability properties, along with kits of pro-toothpaste, allergen/extracts of allergens, and optionally compounding means and/or specialized toothbrushes are provided. Toothpastes suitable and effective for OMIT and methods for managing allergic symptoms and for reducing risk of allergy in people without symptoms employing the pro-toothpastes, toothpastes and kits of the invention are also disclosed.

The present invention provides silk fibroin micro-particles having a high crystallinity index (1.3-1.5) and low sphericity index (≤0.01) and a process for the preparation thereof. The high crystallinity index confers longer degradation periods to the instant silk fibroin micro-particles, therefore facilitating their use in biomedical applications.

A method for reducing the appearance of a skin pore in skin of a subject in need thereof is disclosed. The method can include topically applying to the skin pore a composition comprising effective amount of Albizia julibrissin bark extract, and hydrolyzed soy flour, wherein topical application of the composition reduces the appearance of the size of the skin pore.

The present invention relates to bioceramics obtained from shark teeth, either from tooth enamel, dentine, or a mixture of both, for its use in the treatment of hard tissue injuries or pathologies. The invention can also be used in a dentifrice or mouthwash for the prevention of dental caries, remineralization of teeth or to inhibit dental sensitivity.

The present disclosure relates to compositions capable of absorbing UVA and UVB light. In particle, the present disclosure relates to UV screening compositions comprising at least a portion of LITE-1 polypeptides which are capable of absorbing UV light (e.g., UV-A and/or UV-B light).

The present invention relates to a drug-coated microneedle and a method of manufacturing the same, and more particularly to a drug-coated microneedle that delivers a drug by physically piercing the stratum corneum of the skin and a method of manufacturing the same. The drug-coated microneedle is represented by Chemical Formula 1 below, and is capable of releasing a drug through a redox reaction after penetration into the skin. The drug-coated microneedle according to the present invention is capable of effectively delivering a drug having excellent functionality but low skin permeability, and is thus useful as a material for functional cosmetics for whitening, wrinkle reduction, inflammation reduction and the like. [Chemical Formula 1] MN-S—S-D. In Chemical Formula 1, MN is a silica-(SiO.sub.2)-containing microneedle, S—S is a disulfide bond, and D is a drug.

A cosmetic composition including, in a continuous aqueous phase, at least one colouring agent chosen from hydrophobic treated nacres, at least one hydrophilic gelling agent and water. Also, a method for preparing such a cosmetic composition, to a method for makeup of keratin materials using same, and to the use of this cosmetic composition in order to obtain an aqueous metallic effect or “mirror effect” on the keratin materials.

The present invention relates to cosmetic compositions obtained or obtainable from Salmonidae hatching fluid, methods of producing said compositions and their use in various cosmetic applications to the skin, particularly for reducing or preventing the cosmetic appearance or prevalence of wrinkles, fine lines, hyperpigmentation, laxity, dry skin, scaling and/or transepidermal water loss in skin of a mammalian animal.