A method for increasing bioavailability of natural bioactive molecule using biopolymer complexation technology is provided. The method includes integrating the natural bioactive molecule in the form of nutraceuticals formulations, antioxidants, supplements, and herbs with the cellulose derivatives by modifying surface of the cellulose derivatives with the natural bioactive molecule through hydrogen bonding and ionic interaction between functional groups and forming a complex of natural bioactive molecule and cellulose derivatives. The complex of natural bioactive molecule and cellulose derivatives absorbed in to blood stream as a single entity and dissociates once it is absorbed that subsequently enhances the bioavailability of the natural bioactive molecule.

A water-insoluble composition, solid in appearance at a temperature of less than or equal to 20 C., comprising, for 100% of the mass of same: X1% by mass of at least one lipophilic surfactant having a value HLB, H1, greater than or equal to 1 and less than 10; X2% by mass of at least one hydrophilic surfactant having a value HLB, H2, greater than or equal to 10 and less than or equal to 20; characterised by the fact that the HLB of same=X1.H1+X2.H2, X1 and X2 varying from 2 to 60, and characterised in that it is free of acrylic polymer and/or of acetate succinate.

The present invention relates to kinase inhibitor C.sub.8-C.sub.16 aliphatic sulfate salts, compositions containing kinase inhibitor C.sub.8-C.sub.16 aliphatic sulfate salts and uses thereof.

The present disclosure relates to a composition for preventing or treating metabolic diseases, the composition containing Artemisiae capillaris Herba and Citrus unshiu Peel complex extracts as active ingredients. Specifically, in the Artemisiae capillaris Herba and Citrus unshiu Peel complex extracts according to the present disclosure, the content of ingredients useful for prevention of metabolic diseases including obesity is much higher than in extracts obtained only from Artemisiae capillaris Herba. In addition, when a high-fat diet mouse model is administered the complex extracts, the levels of total cholesterol, LDL, and triglycerides in the blood are reduced. Accordingly, the complex extracts of the present disclosure may be used as a composition or functional material for preventing or treating metabolic diseases including obesity, hyperlipidemia, and hypercholesterolemia.

An effervescent tablet that exhibits rapid disintegration is disclosed. The effervescent tablet includes an effervescent agent that includes an acid and a base, a crystalline sugar binder selected from the group consisting of crystalline dextrose, crystalline sucrose, crystalline fructose, and combinations thereof, the crystalline sugar binder being essentially free of excipients, a sweetener that includes at least one of Stevia and Monk fruit, a flavor agent that includes a gum Arabic carrier, and optionally a lubricant derived from rice hulls (e.g., a multi-component integral lubricant).

An effervescent tablet that exhibits rapid disintegration is disclosed. The effervescent tablet includes an effervescent agent that includes an acid and a base, a directly compressible sugar binder, a sweetener that includes at least one of Stevia and Monk fruit, a flavor agent that includes a gum Arabic carrier, and a lubricant derived from rice hulls.

An aqueous liquid suspension containing a coated drug-ion exchange resin complex comprising a core composed of an amphetamine complexed with a pharmaceutically acceptable ion-exchange resin and an uncoated amphetamine-ion exchange resin complex is provided. The coated amphetamine-ion exchange resin complex is in admixture with a polymer to form a matrix. Methods of making the coated complex and the liquid suspension are described.

The present invention provides formulation/composition comprising phytonutrients with natural chlorotoxins for targeting cancer, infection, inflammation and pain without any side effects and a method for synthesizing the same. The raw materials are cleaned and dried and to prepare coarse powder of 40 mesh size, extracted with solvent (comprising water: alcohol in a ratio of 40:60) in a ratio of 4:1 with overnight soaking. Prior to cold extraction, the mixture is macerated for 4 hours. The mixture is refluxed for 2 hours at 80 C. The addition of ethanol, maceration and refluxing steps are repeated three times and above solvent is added, if required. The residue is checked for complete extraction after every refluxing step. The extract/residue is filtered and concentrated under vacuum. The extract/residue is vacuum tray dried at 70-80 C. for 12 hours. The extract/residue is scraped and dried lumps of the extract/residue are milled. Additional natural product powders are added to the milled powder. The final extract/residue is sieved and packed.

Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.

Provided herein are compositions comprising a carrier and one or more bioactive agents in which one or more bioactive agents are incorporated into said carrier. Sugars that are naturally present with one or more bioactive agents as mixture are preferentially excluded out of said carrier in the composition. The compositions have wide applications including, but not limited to food and beverage industries. Also provided are methods of incorporating one or more bioactive agents into a carrier, compositions comprising a carrier and one or more bioactive agents and use of such methods and compositions, and kits. The methods are useful for (a) improving color, thermal, photo, and oxidative stability of bioactive agents, e.g., natural food colorants and other bioactive ingredients, (b) reducing and eliminating the usage of artificial chemicals such as sacrificial antioxidants and metal ion chelators that are used to improve bioactive stability.