Described herein is a method of treating pain by administering to a subject in need of treatment for pain a pharmaceutical composition including a therapeutically effective amount of margaric acid. Also described are pharmaceutical compositions such as topical and transdermal compositions including margaric acid and a pharmaceutically acceptable excipient. Further described is a composition for the treatment of pain including margaric acid, eicosapentaenoic acid, and a pharmaceutically acceptable excipient.

Pharmaceutical compositions for treating acne, photoaging, and uneven pigmentation comprising three distinct pharmaceutical ingredients are described. Methods for the treatment of acne, photoaging, and uneven pigmentation using the compositions are also described.

Pharmaceutical compositions for treating acne, photoaging, and uneven pigmentation comprising three distinct pharmaceutical ingredients are described. Methods for the treatment of acne, photoaging, and uneven pigmentation using the compositions are also described.

The present invention relates to the use of pomegranate oil and fractions thereof for preventing and treating neurodegenarative diseases. Particularly, the present invention relates to emulsions of the pomegranate oil or fractions thereof for the prevention and treatment of brain diseases, including Creutzfeldt-Jacob disease (CJD) and multiple sclerosis (MS).

The present invention relates to the use of pomegranate oil and fractions thereof for preventing and treating neurodegenarative diseases. Particularly, the present invention relates to emulsions of the pomegranate oil or fractions thereof for the prevention and treatment of brain diseases, including Creutzfeldt-Jacob disease (CJD) and multiple sclerosis (MS).

The present invention discloses a sunflower seed composition rich in pleasant prohormone and anti-depression application thereof, and belongs to the field of extraction and application of natural products. Sunflower seeds used in the composition provided by the present invention are rich in tryptophan and have a high tryptophan/neutral amino acid ratio. After defatting treatment and chlorogenic acid removal treatment, and added part can increase a glycemic index. Glucose and vitamins for promoting absorption conversion of tryptophan and ω-3 fatty acids beneficial to nervous activities enable the sunflower seeds to have a better anti-depression effect. The sunflower seed composition of the present invention can improve concentrations of a monoamine neurotransmitter (serotonin) and dopamine in the brain and has a very good effect of ameliorating and treating depression. This composition uses natural sunflower seeds as raw material and is remarkable in anti-depression effect, rich in source and free of side effects.

The present invention discloses a sunflower seed composition rich in pleasant prohormone and anti-depression application thereof, and belongs to the field of extraction and application of natural products. Sunflower seeds used in the composition provided by the present invention are rich in tryptophan and have a high tryptophan/neutral amino acid ratio. After defatting treatment and chlorogenic acid removal treatment, and added part can increase a glycemic index. Glucose and vitamins for promoting absorption conversion of tryptophan and ω-3 fatty acids beneficial to nervous activities enable the sunflower seeds to have a better anti-depression effect. The sunflower seed composition of the present invention can improve concentrations of a monoamine neurotransmitter (serotonin) and dopamine in the brain and has a very good effect of ameliorating and treating depression. This composition uses natural sunflower seeds as raw material and is remarkable in anti-depression effect, rich in source and free of side effects.

This disclosure relates to methods of use related to omega-3 very-long-chain polyunsaturated fatty acids (n-3 VLC-PUFA) and their hydroxylated derivatives known as elovanoids to alleviate a symptom of, treat, or prevent disease. Furthermore, this invention is directed to compositions and methods for modulating VLC-PUFA bioactivity and availability.

This disclosure relates to methods of use related to omega-3 very-long-chain polyunsaturated fatty acids (n-3 VLC-PUFA) and their hydroxylated derivatives known as elovanoids to alleviate a symptom of, treat, or prevent disease. Furthermore, this invention is directed to compositions and methods for modulating VLC-PUFA bioactivity and availability.

The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark Extract, and 0.2 to 5% by weight of Vitamin E.