Patent classifications
A61K31/23
GLYCERYL LAURATES AND METHODS OF USING THE SAME
A method of promoting muscle growth consisting of providing a dietary supplement containing an effective amount of glyceryl laurates to a user. A composition for promoting muscle growth containing an effective amount of glyceryl laurates.
GLYCERYL LAURATES AND METHODS OF USING THE SAME
A method of promoting muscle growth consisting of providing a dietary supplement containing an effective amount of glyceryl laurates to a user. A composition for promoting muscle growth containing an effective amount of glyceryl laurates.
METHODS FOR THE TREATMENT OF INFANTILE SPASMS USING MEDIUM CHAIN TRIGLYCERIDES
The present disclosure relates to methods for the treatment of Infantile Spasms and/or the prevention of spasms of Infantile spasms. The methods include administering compositions comprising at least one compound capable of elevating ketone body concentrations in a subject in need thereof (e.g., ketogenic compounds), administered in an amount effective for treatment of Infantile Spasms and or the prevention of spams of Infantile Spasms. In one embodiment, the composition includes medium chain triglycerides (MCT). The composition may be administered as an oral dosage forms, in particular, a nutritional drink comprising at least one compound capable of elevating ketone body concentrations in a subject.
METHODS FOR THE TREATMENT OF INFANTILE SPASMS USING MEDIUM CHAIN TRIGLYCERIDES
The present disclosure relates to methods for the treatment of Infantile Spasms and/or the prevention of spasms of Infantile spasms. The methods include administering compositions comprising at least one compound capable of elevating ketone body concentrations in a subject in need thereof (e.g., ketogenic compounds), administered in an amount effective for treatment of Infantile Spasms and or the prevention of spams of Infantile Spasms. In one embodiment, the composition includes medium chain triglycerides (MCT). The composition may be administered as an oral dosage forms, in particular, a nutritional drink comprising at least one compound capable of elevating ketone body concentrations in a subject.
FATTY ACID TREATMENT FOR CARDIAC PATIENTS
A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial β-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
FATTY ACID TREATMENT FOR CARDIAC PATIENTS
A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial β-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
Ophthalmic Composition
The present invention relates to an ophthalmic composition for suppressing eye dryness, comprising at least one selected from the group consisting of chondroitin sulfate having a weight average molecular weight of 30,000 to 50,000 and a salt thereof.
Ophthalmic Composition
The present invention relates to an ophthalmic composition for suppressing eye dryness, comprising at least one selected from the group consisting of chondroitin sulfate having a weight average molecular weight of 30,000 to 50,000 and a salt thereof.
FORMULATIONS HAVING ANTI-INFLAMMATORY ACTIVITY AND ANTIMICROBIAL ACTIVITY AGAINST GRAM-POSITIVE BACTERIA
Novel active compositions having antimicrobial and anti-inflammatory activity are described, the activity provided by an active component prepared in a suspension, the active component being at least a single chain fatty acid having a carbon length of 12, or between 12 and no more than 18. The fatty acid may be esterified and/or ethylated or methylated. As an antimicrobial the active component has activity against one or more microorganisms including Staphylococcus spp., Streptococcus spp., Mycobacterium spp., Clostridium spp., and Candida spp., with an MIC as low as 0.0018 μg/ml. As an anti-inflammatory, it is at least as or is more effective than cyclosporine in preventing T-cell proliferation in response to a trigger, such as stimulation by the one or more microorganisms. The active component is more active when combined with a phospholipid (e.g., lecithin, phosphatidylcholine) and caused to form liposomal nanoparticles. It is also more active when caused to form coated liposomal nanoparticles. Compositions with said active components may be provided internally and/or topically on a surface or on skin.
FORMULATIONS HAVING ANTI-INFLAMMATORY ACTIVITY AND ANTIMICROBIAL ACTIVITY AGAINST GRAM-POSITIVE BACTERIA
Novel active compositions having antimicrobial and anti-inflammatory activity are described, the activity provided by an active component prepared in a suspension, the active component being at least a single chain fatty acid having a carbon length of 12, or between 12 and no more than 18. The fatty acid may be esterified and/or ethylated or methylated. As an antimicrobial the active component has activity against one or more microorganisms including Staphylococcus spp., Streptococcus spp., Mycobacterium spp., Clostridium spp., and Candida spp., with an MIC as low as 0.0018 μg/ml. As an anti-inflammatory, it is at least as or is more effective than cyclosporine in preventing T-cell proliferation in response to a trigger, such as stimulation by the one or more microorganisms. The active component is more active when combined with a phospholipid (e.g., lecithin, phosphatidylcholine) and caused to form liposomal nanoparticles. It is also more active when caused to form coated liposomal nanoparticles. Compositions with said active components may be provided internally and/or topically on a surface or on skin.