The lyophilized formulation of stem cell-derived exosomes and the anti-inflammatory composition including the same as an active ingredient is able to stabilize stem cell-derived exosomes and exhibit excellent anti-inflammatory effects, and particularly, exhibit remarkable anti-inflammatory effects as compared with not-lyophilized stem cell-derived exosomes isolated and purified from conditioned media of stem cells. Therefore, the lyophilized formulation of stem cell-derived exosomes and the anti-inflammatory composition including the same as an active ingredient is able to effectively prevent, suppress, alleviate, ameliorate or treat inflammatory response or inflammatory diseases.

Disclosed herein are contraceptive medical devices that include at least a polymeric ring, a porous barrier material and an injection molding guide, where the guide may be symmetrical and/or have one or a plurality of planar surfaces, where the device may optionally administer at least one active agent.

Disclosed herein are contraceptive medical devices that include at least a polymeric ring, a porous barrier material and an injection molding guide, where the guide may be symmetrical and/or have one or a plurality of planar surfaces, where the device may optionally administer at least one active agent.

Compositions and methods for reprogramming glial cells into neurons are provided. The method entails using a combination of insulin and forskolin generate neurons. The neurons may be generated by converting glial cells into the neurons. The compositions and methods may also include one or both of Vitamin C (VC) and Crizotinub (Cri). Articles of manufacture are provided which include at least one pharmaceutical formulation, packaging, and printed material providing an indication and/or instruction for using the described compounds.

Compositions and methods for reprogramming glial cells into neurons are provided. The method entails using a combination of insulin and forskolin generate neurons. The neurons may be generated by converting glial cells into the neurons. The compositions and methods may also include one or both of Vitamin C (VC) and Crizotinub (Cri). Articles of manufacture are provided which include at least one pharmaceutical formulation, packaging, and printed material providing an indication and/or instruction for using the described compounds.

Compositions and methods for reprogramming glial cells into neurons are provided. The method entails using a combination of insulin and forskolin generate neurons. The neurons may be generated by converting glial cells into the neurons. The compositions and methods may also include one or both of Vitamin C (VC) and Crizotinub (Cri). Articles of manufacture are provided which include at least one pharmaceutical formulation, packaging, and printed material providing an indication and/or instruction for using the described compounds.

Described herein are compositions comprising capsaicin and methods of treating muscle cramping in a subject, comprising orally administering to the subject a composition comprising capsaicin and an excipient.

Described herein are compositions comprising capsaicin and methods of treating muscle cramping in a subject, comprising orally administering to the subject a composition comprising capsaicin and an excipient.

The present invention relates to the use of a starch nanoparticle loaded with at least one active molecule of interest to feed zooplankton, in particular a living prey chosen from rotifers, brine shrimp and copepods. In particular, the invention relates to the use of this loaded starch nanoparticle to increase the size and/or density and/or egg-laying rate of this zooplankton, and/or the hatching rate of the eggs thereof

The present invention relates to the use of a starch nanoparticle loaded with at least one active molecule of interest to feed zooplankton, in particular a living prey chosen from rotifers, brine shrimp and copepods. In particular, the invention relates to the use of this loaded starch nanoparticle to increase the size and/or density and/or egg-laying rate of this zooplankton, and/or the hatching rate of the eggs thereof