The present invention includes novel compounds and methods for preventing or treating diseases associated with N-linked glycosylation in a subject in need thereof. The methods comprise administering to the subject an effective amount of at least one compound of the invention.

The present invention includes novel compounds and methods for preventing or treating diseases associated with N-linked glycosylation in a subject in need thereof. The methods comprise administering to the subject an effective amount of at least one compound of the invention.

Methods of treating patients suffering from or exhibiting symptoms of mental, behavioral, and/or cognitive disorders with azelastine or a pharmaceutically acceptable salt of azelastine are disclosed.

Disclosed herein is a method against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The method includes administering to a subject in need thereof a first active ingredient selected from the group consisting of methotrexate (MIX) and a pharmaceutically acceptable salt thereof, and a second active ingredient selected from the group consisting of remdesivir and a pharmaceutically acceptable salt thereof. A molar ratio of the first active ingredient to the second active ingredient ranges from 1:13 to 1:25.

Disclosed herein is a method against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The method includes administering to a subject in need thereof a first active ingredient selected from the group consisting of methotrexate (MIX) and a pharmaceutically acceptable salt thereof, and a second active ingredient selected from the group consisting of remdesivir and a pharmaceutically acceptable salt thereof. A molar ratio of the first active ingredient to the second active ingredient ranges from 1:13 to 1:25.

The invention relates to a sustained release biodegradable ocular implant containing a tyrosine kinase inhibitor dispersed in a hydrogel for the treatment of a retinal disease for an extended period of time.

The invention relates to a sustained release biodegradable ocular implant containing a tyrosine kinase inhibitor dispersed in a hydrogel for the treatment of a retinal disease for an extended period of time.

Described herein are PPARα agonists, including, but not limited to, endocannabinoids that can be used for treatment of a neuropsychiatric disorder and/or symptom thereof. Also described herein are pharmaceutical formulations containing an effective amount of a PPARα agonists, including but not limited to endocannabinoids, where the effective amount is effective for treating a neuropsychiatric disorder and/or symptom thereof. Also described herein are methods of treating a neuropsychiatric disorder and/or a symptom thereof in a subject in need thereof.

Described herein are PPARα agonists, including, but not limited to, endocannabinoids that can be used for treatment of a neuropsychiatric disorder and/or symptom thereof. Also described herein are pharmaceutical formulations containing an effective amount of a PPARα agonists, including but not limited to endocannabinoids, where the effective amount is effective for treating a neuropsychiatric disorder and/or symptom thereof. Also described herein are methods of treating a neuropsychiatric disorder and/or a symptom thereof in a subject in need thereof.

Provided is a composition comprising a phenyl pyrrole aminoguanidine derivative for use in a method of treating viral disorders and diseases, including symptomatic viral disorders and diseases, including symptomatic COVID-19.