This invention relates to a method of preventing or treating a disease, disorder or condition induced by retina ischemia comprising administrating a subject a therapeutically effective amount of a RBP2 inhibitor for preventing or treating a disease, disorder or condition induced by retina ischemia.

This invention relates to a method of preventing or treating a disease, disorder or condition induced by retina ischemia comprising administrating a subject a therapeutically effective amount of a RBP2 inhibitor for preventing or treating a disease, disorder or condition induced by retina ischemia.

Disclosed is a traditional Chinese medicinal composition for treating neurogenic pulmonary edema. The traditional Chinese medicinal composition is mainly prepared from Notopterygium root, angelicae pubescentis radix, poria cocos, radix saposhnikoviae, herba schizonepetae, rhizoma chuanxiong, platycodonis radix, radix bupleuri, common hogfennel root, fructus aurantii, and licorice root. The traditional Chinese medicinal composition can improve a lung index and lung wet weight/dry weight of a rat with neurogenic pulmonary edema, and has a therapeutic effect on the neurogenic pulmonary edema.

Disclosed is a traditional Chinese medicinal composition for treating neurogenic pulmonary edema. The traditional Chinese medicinal composition is mainly prepared from Notopterygium root, angelicae pubescentis radix, poria cocos, radix saposhnikoviae, herba schizonepetae, rhizoma chuanxiong, platycodonis radix, radix bupleuri, common hogfennel root, fructus aurantii, and licorice root. The traditional Chinese medicinal composition can improve a lung index and lung wet weight/dry weight of a rat with neurogenic pulmonary edema, and has a therapeutic effect on the neurogenic pulmonary edema.

The present invention relates to a pharmaceutical composition for conditioning dampness-heat. The pharmaceutical composition consists of licorice root, forsythia shell, tree peony root bark, baical skullcap root, cassia twig, root of Chinese thorowax, Oroxylum indicum seed, mulberry leaf, prunella vulgaris, honeysuckle and perilla leaf. Herein, ratio of the licorice root to forsythia shell to tree peony root bark to baical skullcap root to cassia twig to root of Chinese thorowax to Oroxylum indicum seed to mulberry leaf to prunella vulgaris to honeysuckle and to perilla leaf is about 3:10:10:10:8:10:2:10:5:7:3.

The present invention relates to a pharmaceutical composition for conditioning dampness-heat. The pharmaceutical composition consists of licorice root, forsythia shell, tree peony root bark, baical skullcap root, cassia twig, root of Chinese thorowax, Oroxylum indicum seed, mulberry leaf, prunella vulgaris, honeysuckle and perilla leaf. Herein, ratio of the licorice root to forsythia shell to tree peony root bark to baical skullcap root to cassia twig to root of Chinese thorowax to Oroxylum indicum seed to mulberry leaf to prunella vulgaris to honeysuckle and to perilla leaf is about 3:10:10:10:8:10:2:10:5:7:3.

Compositions comprising extracts prepared from mixtures of the herbal plants Radix Bupleurum chinense DC (B), Rhizoma Corydalis yanhusuo WT Wang (Y), Caulis Polygonum multiflorum Thunb (P) and Flos Albizia julibrissin Durazz (A) are provided. The BYP, BYA, BPA, BY, BP, YP and BYPA extracts significantly decreased one or more of the effects of accelerated aging in mice exposed to D-galactose, including spatial memory deficit, and elevated oxidative stress marker malondialdehyde and pro-inflammatory cytokines TNF-alpha and IL-6 in the brain, indicating efficacy in reducing the damage of aging, and preventing and treating Alzheimer's disease and/or Parkinson's disease. Anxiolysis by the BYA, BPA, YPA, BA and PA extracts indicates efficacy for treating anxiety disorders, and the sedative effect of the BYA, YPA and PA extracts indicates efficacy for treating sleep disorders. None of the extracts significantly induced alteration in locomotor activity, decreased muscle coordination, or anterograde amnesia at the maximum oral dose tested.

Compositions comprising extracts prepared from mixtures of the herbal plants Radix Bupleurum chinense DC (B), Rhizoma Corydalis yanhusuo WT Wang (Y), Caulis Polygonum multiflorum Thunb (P) and Flos Albizia julibrissin Durazz (A) are provided. The BYP, BYA, BPA, BY, BP, YP and BYPA extracts significantly decreased one or more of the effects of accelerated aging in mice exposed to D-galactose, including spatial memory deficit, and elevated oxidative stress marker malondialdehyde and pro-inflammatory cytokines TNF-alpha and IL-6 in the brain, indicating efficacy in reducing the damage of aging, and preventing and treating Alzheimer's disease and/or Parkinson's disease. Anxiolysis by the BYA, BPA, YPA, BA and PA extracts indicates efficacy for treating anxiety disorders, and the sedative effect of the BYA, YPA and PA extracts indicates efficacy for treating sleep disorders. None of the extracts significantly induced alteration in locomotor activity, decreased muscle coordination, or anterograde amnesia at the maximum oral dose tested.

Compositions comprising extracts prepared from mixtures of the herbal plants Radix Bupleurum chinense DC (B), Rhizoma Corydalis yanhusuo WT Wang (Y), Caulis Polygonum multiflorum Thunb (P) and Flos Albizia julibrissin Durazz (A) are provided. The BYP, BYA, BPA, BY, BP, YP and BYPA extracts significantly decreased one or more of the effects of accelerated aging in mice exposed to D-galactose, including spatial memory deficit, and elevated oxidative stress marker malondialdehyde and pro-inflammatory cytokines TNF-alpha and IL-6 in the brain, indicating efficacy in reducing the damage of aging, and preventing and treating Alzheimer's disease and/or Parkinson's disease. Anxiolysis by the BYA, BPA, YPA, BA and PA extracts indicates efficacy for treating anxiety disorders, and the sedative effect of the BYA, YPA and PA extracts indicates efficacy for treating sleep disorders. None of the extracts significantly induced alteration in locomotor activity, decreased muscle coordination, or anterograde amnesia at the maximum oral dose tested.

A traditional Chinese medicine compound preparation with pure herbs for detoxification and Fukang, and a preparation method thereof, wherein the traditional Chinese medicine compound preparation for detoxification and Fukang includes the detoxification preparation, Fukang preparation, as well as dryness-removing and pain-relieving preparation; its preparation method includes Die Wan manufacturing process and capsule manufacturing process, the detoxification preparation and Fukang preparation adopt the Die Wan manufacturing process, the dryness-removing and pain-relieving preparation adopt the capsule manufacturing process; the invention is a traditional Chinese medicine compound preparation with pure herbs, which is a universal type for any single drug and mixed drugs, with short treatment period, quick effect, less cost, detoxification in one week, keeping people strong and healthy in another week, and no withdrawal syndrome, no drug dependence, no toxic side effects and good anti-relapse effect; it can greatly alleviate the pain of abrupt withdrawal during the detoxification process.