Patent classifications
A61K36/233
Pharmaceutical composition containing combination extracts of Moutan Root Bark, Angelica Dahurica Root, bupleurum root or fractions thereof for prevention and treatment of neurodegenerative disorder
The present invention relates to a pharmaceutical composition for treating and preventing degenerative neurological disorders, containing, as an active ingredient, a mixture extract of two or more types selected from the group consisting of Moutan Root Bark, Angelica Dahurica Root, and Bupleurum Root, or a fraction thereof. Specifically, the extract of the mixture of the present invention exhibits a recovery effect on mitochondrial function damage, a relieving effect on endoplasmic reticulum stress and also exhibits simultaneously an inhibitory effect on inflammatory response, which are remarkably improved compared with those exhibited in an in vitro single extract, and the extract of the mixture significantly exhibits an improvement effect on motor coordination and a protective effect on dopaminergic neurons in a Parkinson's disease animal model, and thus the extract of the mixture of the present invention or a fraction thereof can be useful as an active ingredient of a pharmaceutical composition for treating and preventing degenerative neurological disorders.
Pharmaceutical composition containing combination extracts of Moutan Root Bark, Angelica Dahurica Root, bupleurum root or fractions thereof for prevention and treatment of neurodegenerative disorder
The present invention relates to a pharmaceutical composition for treating and preventing degenerative neurological disorders, containing, as an active ingredient, a mixture extract of two or more types selected from the group consisting of Moutan Root Bark, Angelica Dahurica Root, and Bupleurum Root, or a fraction thereof. Specifically, the extract of the mixture of the present invention exhibits a recovery effect on mitochondrial function damage, a relieving effect on endoplasmic reticulum stress and also exhibits simultaneously an inhibitory effect on inflammatory response, which are remarkably improved compared with those exhibited in an in vitro single extract, and the extract of the mixture significantly exhibits an improvement effect on motor coordination and a protective effect on dopaminergic neurons in a Parkinson's disease animal model, and thus the extract of the mixture of the present invention or a fraction thereof can be useful as an active ingredient of a pharmaceutical composition for treating and preventing degenerative neurological disorders.
COMPOSITION FOR TREATING FATTY LIVER
A composition for treating fatty liver which comprises extracts of ginseng, Atractylodes rhizome, Crataegus cuneate, Alisma tuber and Cassia obtusifolia L.
COMPOSITION FOR TREATING FATTY LIVER
A composition for treating fatty liver which comprises extracts of ginseng, Atractylodes rhizome, Crataegus cuneate, Alisma tuber and Cassia obtusifolia L.
Traditional Chinese medicine composition, and preparation method therefor and application thereof
A traditional Chinese medicine composition, and preparation method, and application thereof. The traditional Chinese medicine composition includes the following raw medicines in parts by weight: 10-35 parts of root of Chinese thorowax, 5-25 parts of immature bitter orange, 3-20 parts of fresh root and rhizome of sorrel rhubarb, 3-20 parts of root of baikal skullcap, 3-20 parts of white peony root, 3-15 parts of dried ginger, 5-20 parts of leech, 3-20 parts of root of ural licorice, 3-20 parts of root pilose asiabell, 3-20 parts of rhizome of largehead atractylodes, and 3-25 parts of tuber of pinellia. The traditional Chinese medicine composition has excellent effects in lowering blood lipids and cholesterol levels, particularly in lowering blood triglyceride. The traditional Chinese medicine composition also has excellent effects in slowing formation of atherosclerotic plaques, clearing the atherosclerotic plaques, and preventing and treating atherosclerosis.
Traditional Chinese medicine composition, and preparation method therefor and application thereof
A traditional Chinese medicine composition, and preparation method, and application thereof. The traditional Chinese medicine composition includes the following raw medicines in parts by weight: 10-35 parts of root of Chinese thorowax, 5-25 parts of immature bitter orange, 3-20 parts of fresh root and rhizome of sorrel rhubarb, 3-20 parts of root of baikal skullcap, 3-20 parts of white peony root, 3-15 parts of dried ginger, 5-20 parts of leech, 3-20 parts of root of ural licorice, 3-20 parts of root pilose asiabell, 3-20 parts of rhizome of largehead atractylodes, and 3-25 parts of tuber of pinellia. The traditional Chinese medicine composition has excellent effects in lowering blood lipids and cholesterol levels, particularly in lowering blood triglyceride. The traditional Chinese medicine composition also has excellent effects in slowing formation of atherosclerotic plaques, clearing the atherosclerotic plaques, and preventing and treating atherosclerosis.
Phytochemical/ nutraceutical composition for multimodal prophylaxis against and treatment of viral and bacterial infection and inflammation
A phytochemical and nutraceutical composition and method for protection against a wide spectrum of viral and bacterial infections, including Covid-19, and for treatment of established infection and infectious inflammation. The composition includes a novel combination of vitamin, mineral, nutraceutical and phytochemical supplements. The composition of supplements and method may be compounded as a pill, tablet, powder, capsule or liquid be taken orally one or more times per day. Vitamin C and vitamin E along with zinc complexed with pyrithione or citrate are used in conjunction with nutraceuticals and phytochemicals provided, respectively, as immune boosters and antiviral agents along with anti-inflammatory nutraceuticals and phytochemicals.
Phytochemical/ nutraceutical composition for multimodal prophylaxis against and treatment of viral and bacterial infection and inflammation
A phytochemical and nutraceutical composition and method for protection against a wide spectrum of viral and bacterial infections, including Covid-19, and for treatment of established infection and infectious inflammation. The composition includes a novel combination of vitamin, mineral, nutraceutical and phytochemical supplements. The composition of supplements and method may be compounded as a pill, tablet, powder, capsule or liquid be taken orally one or more times per day. Vitamin C and vitamin E along with zinc complexed with pyrithione or citrate are used in conjunction with nutraceuticals and phytochemicals provided, respectively, as immune boosters and antiviral agents along with anti-inflammatory nutraceuticals and phytochemicals.
Chinese herbal oral paste for conditioning qi depression constitution and processing method therefor
The present application discloses a Chinese herbal oral paste for conditioning qi depression constitution. The Chinese herbal oral paste includes the following components: Chinese thorowax root, debark peony root, licorice, Sichuan lovage rhizome, dried tangerine peel, orange fruit, nutgrass galingale rhizome, mint, fuling, perilla leaf, largehead atractylodes rhizome, fruit of caoguo, common aucklandia root, chinaberry fruit, lychee seed, finger citron, citron fruit, rose flower, citrus aurantium L, silktree albizia bark, nardostachys root, grassleaf sweetflag rhizome, heterophylly falsestarwort root, Chinese yam, white hyacinth bean, dendrobium, turmeric root tuber, donkey-hide gelatin, turtle shell gelatin, tortoise-plastron gelatin, and xylitol. The Chinese herbal oral paste of the present disclosure has a higher drug concentration and good taste, is particularly suitable for health preserving in winter and conditioning the qi depression constitution, will not create negative effects to the human body at all, and is capable of achieving certain efficacy of strengthening physical health.
Chinese herbal oral paste for conditioning qi depression constitution and processing method therefor
The present application discloses a Chinese herbal oral paste for conditioning qi depression constitution. The Chinese herbal oral paste includes the following components: Chinese thorowax root, debark peony root, licorice, Sichuan lovage rhizome, dried tangerine peel, orange fruit, nutgrass galingale rhizome, mint, fuling, perilla leaf, largehead atractylodes rhizome, fruit of caoguo, common aucklandia root, chinaberry fruit, lychee seed, finger citron, citron fruit, rose flower, citrus aurantium L, silktree albizia bark, nardostachys root, grassleaf sweetflag rhizome, heterophylly falsestarwort root, Chinese yam, white hyacinth bean, dendrobium, turmeric root tuber, donkey-hide gelatin, turtle shell gelatin, tortoise-plastron gelatin, and xylitol. The Chinese herbal oral paste of the present disclosure has a higher drug concentration and good taste, is particularly suitable for health preserving in winter and conditioning the qi depression constitution, will not create negative effects to the human body at all, and is capable of achieving certain efficacy of strengthening physical health.