Provided is a composition for alleviating fatigue or enhancing exercise capability including extracts or fractions of Angelica gigas, Cnidium officinale, and Paeonia lactiflora as active ingredients. The composition including the extracts or fractions of Angelica gigas, Cnidium officinale, and Paeonia lactiflora as active ingredients may effectively alleviate fatigue accumulated in the body and enhance exercise capability by multilaterally controlling various factors involved in physical fatigue and/or enhancement of exercise capability. Specifically, the composition may effectively control the factors related to fatigue by increasing the expression level of HO-1 by activating the Nrf-2 pathway. Also, since extracts of natural plants or fractions thereof are used as active ingredients, the composition is completely harmless to the human body and may be used safely.

Provided is a composition for alleviating fatigue or enhancing exercise capability including extracts or fractions of Angelica gigas, Cnidium officinale, and Paeonia lactiflora as active ingredients. The composition including the extracts or fractions of Angelica gigas, Cnidium officinale, and Paeonia lactiflora as active ingredients may effectively alleviate fatigue accumulated in the body and enhance exercise capability by multilaterally controlling various factors involved in physical fatigue and/or enhancement of exercise capability. Specifically, the composition may effectively control the factors related to fatigue by increasing the expression level of HO-1 by activating the Nrf-2 pathway. Also, since extracts of natural plants or fractions thereof are used as active ingredients, the composition is completely harmless to the human body and may be used safely.

The present invention relates to a method for preparing an herbal composition with increased fat-soluble polyphenols, an herbal composition prepared by the method, and a use of the composition. The herbal composition with increased fat-soluble polyphenols of the present invention is characterized by the significantly increased content of fat-soluble polyphenols including decursin, compared with the herbal composition of comparative example, and also demonstrates a significant anti-oxidative activity, immune cell activating effect, and cancer cell growth inhibitory effect, significantly reduces renal toxicity and liver toxicity induced by the anticancer agent cisplatin back so as to be almost normal condition, and significantly inhibits the intestinal crypt loss caused by irradiation, compared with the herbal composition of comparative example. Therefore, the herbal composition with increased fat-soluble polyphenols of the present invention can be effectively used as a composition for cancer treatment, an anti-cancer adjuvant, a composition for enhancing immune function, a composition for protecting a living body, and a composition for preventing side effects of cancer treatment.

The present invention relates to a method for preparing an herbal composition with increased fat-soluble polyphenols, an herbal composition prepared by the method, and a use of the composition. The herbal composition with increased fat-soluble polyphenols of the present invention is characterized by the significantly increased content of fat-soluble polyphenols including decursin, compared with the herbal composition of comparative example, and also demonstrates a significant anti-oxidative activity, immune cell activating effect, and cancer cell growth inhibitory effect, significantly reduces renal toxicity and liver toxicity induced by the anticancer agent cisplatin back so as to be almost normal condition, and significantly inhibits the intestinal crypt loss caused by irradiation, compared with the herbal composition of comparative example. Therefore, the herbal composition with increased fat-soluble polyphenols of the present invention can be effectively used as a composition for cancer treatment, an anti-cancer adjuvant, a composition for enhancing immune function, a composition for protecting a living body, and a composition for preventing side effects of cancer treatment.

The present invention relates to a method for preparing an herbal composition with increased fat-soluble polyphenols, an herbal composition prepared by the method, and a use of the composition. The herbal composition with increased fat-soluble polyphenols of the present invention is characterized by the significantly increased content of fat-soluble polyphenols including decursin, compared with the herbal composition of comparative example, and also demonstrates a significant anti-oxidative activity, immune cell activating effect, and cancer cell growth inhibitory effect, significantly reduces renal toxicity and liver toxicity induced by the anticancer agent cisplatin back so as to be almost normal condition, and significantly inhibits the intestinal crypt loss caused by irradiation, compared with the herbal composition of comparative example. Therefore, the herbal composition with increased fat-soluble polyphenols of the present invention can be effectively used as a composition for cancer treatment, an anti-cancer adjuvant, a composition for enhancing immune function, a composition for protecting a living body, and a composition for preventing side effects of cancer treatment.

The present invention relates to a medicine composition for treatment of bone and joint diseases that has its ingredients (% by weight) as the dried extract of medicinal herbs: 40-75; tortoiseshell extract: 0.1-20; mixed bone extract: 0.1-20; deer antler extract: 0.1-20; salix alba extract: 5-25; nattokinase: 0.1-10; and Na-benzoate: 0-0.5, wherein the herbal medicine mixture comprises the ingredients of: Huang Bai (bark), Liquorice (root/rhizome), Hardy rubber tree (bark), Ox Knee (root), Fang Feng (root), Poria cocos wolf (fruit body), Chinese foxglove (rhizome), Sang Ji Sheng (whole tree), Gentian Root (root), Rhizoma Anemarrhena (rhizome), Peach blossom (blossom), Dried tangerine peel (peel), Chinese peony (root), Dangshen (root), Ginseng (root) Du Huo (root), Dongquai (root), Cinnamon (bough), Xi Xin (root, rhizome), Szechuan lovage (rhizome) and Dwarf umbrella tree (root). The present invention also relates to a process for producing medicine composition for treatment of bone and joint diseases mentioned above.

The present invention relates to a medicine composition for treatment of bone and joint diseases that has its ingredients (% by weight) as the dried extract of medicinal herbs: 40-75; tortoiseshell extract: 0.1-20; mixed bone extract: 0.1-20; deer antler extract: 0.1-20; salix alba extract: 5-25; nattokinase: 0.1-10; and Na-benzoate: 0-0.5, wherein the herbal medicine mixture comprises the ingredients of: Huang Bai (bark), Liquorice (root/rhizome), Hardy rubber tree (bark), Ox Knee (root), Fang Feng (root), Poria cocos wolf (fruit body), Chinese foxglove (rhizome), Sang Ji Sheng (whole tree), Gentian Root (root), Rhizoma Anemarrhena (rhizome), Peach blossom (blossom), Dried tangerine peel (peel), Chinese peony (root), Dangshen (root), Ginseng (root) Du Huo (root), Dongquai (root), Cinnamon (bough), Xi Xin (root, rhizome), Szechuan lovage (rhizome) and Dwarf umbrella tree (root). The present invention also relates to a process for producing medicine composition for treatment of bone and joint diseases mentioned above.

The invention discloses a total extract of Fructus Cnidii, which contains bergamot, the application of the total extract of Fructus Cnidii in preparing medicines for preventing and/or treating allergic dermatosis, psoriasis or herpes zoster, and the construction method of the fingerprint of the total extract of Fructus Cnidii. The invention adopts LC-MS technology to establish the fingerprint of the total extract of Fructus Cnidii, thus effectively improving the quality stability, uniformity and controllability of the total extract of Fructus Cnidii.

The invention discloses a total extract of Fructus Cnidii, which contains bergamot, the application of the total extract of Fructus Cnidii in preparing medicines for preventing and/or treating allergic dermatosis, psoriasis or herpes zoster, and the construction method of the fingerprint of the total extract of Fructus Cnidii. The invention adopts LC-MS technology to establish the fingerprint of the total extract of Fructus Cnidii, thus effectively improving the quality stability, uniformity and controllability of the total extract of Fructus Cnidii.

The present invention relates to a composition for promoting the proliferation of stem cells derived from bone marrow using a palmultang extract, and specifically, to a composition for promoting the proliferation of stem cells derived from bone marrow by administering a granulocyte colony-stimulating factor to a subject and then administering the palmultang extract to the subject. The composition of the present invention remarkably reduces side effects, such as enlargement of the spleen, which are caused by the administration of G-CSF alone for proliferation and differentiation of the stem cells, through administration in combination with the palmultang extract, thereby further promoting the proliferation and differentiation of stem cells.