A61K36/258

DILEUCINE COMPOSITIONS AND METHODS OF USE THEREOF FOR FAT LOSS
20230113817 · 2023-04-13 ·

Described herein are compositions for reducing body weight, reducing body fat, improving body composition and/or preventing obesity and related conditions. In certain aspects, the compositions comprise dileucine, and a pharmaceutically acceptable carrier thereof. In certain embodiments, the composition comprises dileucine and leucine. In further aspects, the dileucine is present from about 10% to 90% (w/w). In further aspects, the dileucine is present from about 20% to 80% (w/w). In further aspects, wherein the dileucine is present from about 30% to 70% (w/w). In further aspects, the dileucine is present from about 40% to 60% (w/w).

PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

Provided is a pharmaceutical composition and application thereof, specifically, said pharmaceutical composition comprises: salvianolic acid B as a first active ingredient; and ginsenoside Rg1 as a second active ingredient, and the weight ratio of the first active ingredient to the second active ingredient being 5: (1-4.5). The pharmaceutical composition has a better active-ingredient proportion than the prior art, has a better therapeutic efficacy in preventing and/or treating ischemic diseases, and ischemia-reperfusion tissue or organ damage, and can be used for treating ischemia and/or ischemia-reperfusion damage of different tissues and organs.

PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

Provided is a pharmaceutical composition and application thereof, specifically, said pharmaceutical composition comprises: salvianolic acid B as a first active ingredient; and ginsenoside Rg1 as a second active ingredient, and the weight ratio of the first active ingredient to the second active ingredient being 5: (1-4.5). The pharmaceutical composition has a better active-ingredient proportion than the prior art, has a better therapeutic efficacy in preventing and/or treating ischemic diseases, and ischemia-reperfusion tissue or organ damage, and can be used for treating ischemia and/or ischemia-reperfusion damage of different tissues and organs.

PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

Provided is a pharmaceutical composition and application thereof, specifically, said pharmaceutical composition comprises: salvianolic acid B as a first active ingredient; and ginsenoside Rg1 as a second active ingredient, and the weight ratio of the first active ingredient to the second active ingredient being 5: (1-4.5). The pharmaceutical composition has a better active-ingredient proportion than the prior art, has a better therapeutic efficacy in preventing and/or treating ischemic diseases, and ischemia-reperfusion tissue or organ damage, and can be used for treating ischemia and/or ischemia-reperfusion damage of different tissues and organs.

COMPOSITIONS AND APPLICATIONS THEREOF

Compositions in homogenised powder form consisting of hydroxypropyl methylcellulose particles, and at least one chemical signalling agent in particle form, and optionally a biologically active agent, wherein the homogenised powder comprises particles having a mean particle diameter of ≥20 μm to ≤500 μmm uses and kits therefor.

COMPOSITIONS AND APPLICATIONS THEREOF

Compositions in homogenised powder form consisting of hydroxypropyl methylcellulose particles, and at least one chemical signalling agent in particle form, and optionally a biologically active agent, wherein the homogenised powder comprises particles having a mean particle diameter of ≥20 μm to ≤500 μmm uses and kits therefor.

Pharmaceutical composition for preventing or treating neurodegenerative diseases including fermented steam-dried ginseng berry
11622983 · 2023-04-11 · ·

The present disclosure relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases, the pharmaceutical composition including a fermented steam-dried ginseng berry as an active ingredient. Specifically, the fermented steam-dried ginseng berry may have a high total ginsenoside and polyphenol content, exhibit antioxidant activity, inhibit acetylcholinesterase, improve cognitive function and spatial perception in animal model of dementias, recover acetylcholine expression and inhibit accumulation of amyloid-beta in brain tissue of the animal model of dementias, inhibit brain damage in animal model of dementias, and promote expression of genes related to brain damage in neuronal cell lines, and accordingly, the fermented steam-dried ginseng berry may be used to treat neurodegenerative diseases, improve cognitive function, and protect brain cells.

Pharmaceutical composition for preventing or treating neurodegenerative diseases including fermented steam-dried ginseng berry
11622983 · 2023-04-11 · ·

The present disclosure relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases, the pharmaceutical composition including a fermented steam-dried ginseng berry as an active ingredient. Specifically, the fermented steam-dried ginseng berry may have a high total ginsenoside and polyphenol content, exhibit antioxidant activity, inhibit acetylcholinesterase, improve cognitive function and spatial perception in animal model of dementias, recover acetylcholine expression and inhibit accumulation of amyloid-beta in brain tissue of the animal model of dementias, inhibit brain damage in animal model of dementias, and promote expression of genes related to brain damage in neuronal cell lines, and accordingly, the fermented steam-dried ginseng berry may be used to treat neurodegenerative diseases, improve cognitive function, and protect brain cells.

HERBAL FORMULATION AND METHOD OF ADMINISTERING THE SAME
20230109311 · 2023-04-06 ·

The present disclosure relates to an herbal composition and a method of administering the composition including administering the composition in pill or capsule form on a routine basis and administering tadalafil on a routine basis in some instances for the purpose of increasing energy, alertness, clarity, memory, and sexual enhancement in individuals, and particularly in males.

HERBAL FORMULATION AND METHOD OF ADMINISTERING THE SAME
20230109311 · 2023-04-06 ·

The present disclosure relates to an herbal composition and a method of administering the composition including administering the composition in pill or capsule form on a routine basis and administering tadalafil on a routine basis in some instances for the purpose of increasing energy, alertness, clarity, memory, and sexual enhancement in individuals, and particularly in males.