A61K36/258

Composition comprising a combined herb extract of <i>Salvia plebia </i>and red ginseng as active ingredients for preventing or treating a respiratory inflammation and the use thereof

The present invention relates to a composition and health functional food for preventing and treating a respiratory inflammation disease using a mixed herbal mixture. Through various experiments, for example, determination of the cell number of BAL (bronchoalveolar lavage) (Experimental Example 1); Determination of CD11b+/Gr-1+ ratio in leukocyte within BAL fluid (Experimental Example 2); Determination of expressed RNA level of inflammatory cytokines in lung tissue (Experimental Example 3); Determination of expressed RNA level of inflammatory cytokines in BALF (Experimental Example 4); Lung histology (Experimental Example 5); Brief Clinical test (Experimental Example 7) etc, it has been verified that the inventive combined extract showed more potent inhibiting effect on respiratory inflammation disease than each herb extract. Therefore, the herbal extract of the present invention can be usefully used in a pharmaceutical composition, health functional food, and health supplement food for preventing and treating respiratory inflammation disease.

Composition comprising a combined herb extract of <i>Salvia plebia </i>and red ginseng as active ingredients for preventing or treating a respiratory inflammation and the use thereof

The present invention relates to a composition and health functional food for preventing and treating a respiratory inflammation disease using a mixed herbal mixture. Through various experiments, for example, determination of the cell number of BAL (bronchoalveolar lavage) (Experimental Example 1); Determination of CD11b+/Gr-1+ ratio in leukocyte within BAL fluid (Experimental Example 2); Determination of expressed RNA level of inflammatory cytokines in lung tissue (Experimental Example 3); Determination of expressed RNA level of inflammatory cytokines in BALF (Experimental Example 4); Lung histology (Experimental Example 5); Brief Clinical test (Experimental Example 7) etc, it has been verified that the inventive combined extract showed more potent inhibiting effect on respiratory inflammation disease than each herb extract. Therefore, the herbal extract of the present invention can be usefully used in a pharmaceutical composition, health functional food, and health supplement food for preventing and treating respiratory inflammation disease.

Composition comprising a combined herb extract of <i>Salvia plebia </i>and red ginseng as active ingredients for preventing or treating a respiratory inflammation and the use thereof

The present invention relates to a composition and health functional food for preventing and treating a respiratory inflammation disease using a mixed herbal mixture. Through various experiments, for example, determination of the cell number of BAL (bronchoalveolar lavage) (Experimental Example 1); Determination of CD11b+/Gr-1+ ratio in leukocyte within BAL fluid (Experimental Example 2); Determination of expressed RNA level of inflammatory cytokines in lung tissue (Experimental Example 3); Determination of expressed RNA level of inflammatory cytokines in BALF (Experimental Example 4); Lung histology (Experimental Example 5); Brief Clinical test (Experimental Example 7) etc, it has been verified that the inventive combined extract showed more potent inhibiting effect on respiratory inflammation disease than each herb extract. Therefore, the herbal extract of the present invention can be usefully used in a pharmaceutical composition, health functional food, and health supplement food for preventing and treating respiratory inflammation disease.

ACTIVATED INSULIN, COMPOUND MOMORDICA CHARANTIA PEPTIDE ORAL MEDICINE FOR TREATMENT OF DIABETES, AND PREPARATION METHOD
20220370541 · 2022-11-24 ·

A compound bitter melon peptide (BMP) oral medicine for activating insulin and treating diabetes, including 20-30 parts by weight of BMP powder, 4-6 parts by weight of Panax quinquefolius, 10-12 parts by weight of Astragalus membranaceus, 3-5 parts by weight of Ganoderma lucidum powder, 8-10 parts by weight of Dioscorea opposita powder, 10-15 parts by weight of wheat bran, 10-12 parts by weight of Psidium guajava leaf powder, 5-10 parts by weight of onion extract, 5-10 parts by weight of Lycium barbarum, 12-15 parts by weight of Gynura procumbens extract, 1-2 parts by weight of coix seed, 5-8 parts by weight of konjac glucomannan, 8-10 parts by weight of lotus leaf and 5-8 parts by weight of xylo-oligosaccharide. A method for preparing the compound bitter melon peptide (BMP) oral medicine is also provided.

ACTIVATED INSULIN, COMPOUND MOMORDICA CHARANTIA PEPTIDE ORAL MEDICINE FOR TREATMENT OF DIABETES, AND PREPARATION METHOD
20220370541 · 2022-11-24 ·

A compound bitter melon peptide (BMP) oral medicine for activating insulin and treating diabetes, including 20-30 parts by weight of BMP powder, 4-6 parts by weight of Panax quinquefolius, 10-12 parts by weight of Astragalus membranaceus, 3-5 parts by weight of Ganoderma lucidum powder, 8-10 parts by weight of Dioscorea opposita powder, 10-15 parts by weight of wheat bran, 10-12 parts by weight of Psidium guajava leaf powder, 5-10 parts by weight of onion extract, 5-10 parts by weight of Lycium barbarum, 12-15 parts by weight of Gynura procumbens extract, 1-2 parts by weight of coix seed, 5-8 parts by weight of konjac glucomannan, 8-10 parts by weight of lotus leaf and 5-8 parts by weight of xylo-oligosaccharide. A method for preparing the compound bitter melon peptide (BMP) oral medicine is also provided.

ACTIVATED INSULIN, COMPOUND MOMORDICA CHARANTIA PEPTIDE ORAL MEDICINE FOR TREATMENT OF DIABETES, AND PREPARATION METHOD
20220370541 · 2022-11-24 ·

A compound bitter melon peptide (BMP) oral medicine for activating insulin and treating diabetes, including 20-30 parts by weight of BMP powder, 4-6 parts by weight of Panax quinquefolius, 10-12 parts by weight of Astragalus membranaceus, 3-5 parts by weight of Ganoderma lucidum powder, 8-10 parts by weight of Dioscorea opposita powder, 10-15 parts by weight of wheat bran, 10-12 parts by weight of Psidium guajava leaf powder, 5-10 parts by weight of onion extract, 5-10 parts by weight of Lycium barbarum, 12-15 parts by weight of Gynura procumbens extract, 1-2 parts by weight of coix seed, 5-8 parts by weight of konjac glucomannan, 8-10 parts by weight of lotus leaf and 5-8 parts by weight of xylo-oligosaccharide. A method for preparing the compound bitter melon peptide (BMP) oral medicine is also provided.

COMPOSITION, ARTICLE AND METHOD FOR AFFECTING A MAMMAL
20230056488 · 2023-02-23 ·

Compositions, articles and methods for treating sleeplessness, anxiety, pain or inflammation include: (i) one or more pharmacologically active, non-psychoactive cannabinoids; (ii) one or more active agents; and an optional carrier or matrix. The optional carrier or matrix may comprise ingredients such as solvents, solid or dissolvable supports, fillers, flavorants, flavor or taste masking agents, and other adjuvants that provide the composition in a useful form factor configured for easy administration to a mammal of an appropriate pharmacological dosage of the active ingredients.

COMPOSITION, ARTICLE AND METHOD FOR AFFECTING A MAMMAL
20230056488 · 2023-02-23 ·

Compositions, articles and methods for treating sleeplessness, anxiety, pain or inflammation include: (i) one or more pharmacologically active, non-psychoactive cannabinoids; (ii) one or more active agents; and an optional carrier or matrix. The optional carrier or matrix may comprise ingredients such as solvents, solid or dissolvable supports, fillers, flavorants, flavor or taste masking agents, and other adjuvants that provide the composition in a useful form factor configured for easy administration to a mammal of an appropriate pharmacological dosage of the active ingredients.

Stenting-Free Pharmaceutical Composition for Treatment of Cardiovascular and Cerebrovascular Disease
20220362307 · 2022-11-17 ·

The present disclosure provides a traditional Chinese medicine (TCM) composition for the treatment of cardiovascular and cerebrovascular diseases and use thereof, and belongs to the technical field of TCM. The composition for the treatment of cardiovascular and cerebrovascular diseases provided by the present disclosure includes the following raw materials: Radix Panacis Quinquefolii, Pheretima, Radix et Rhizoma Salviae Miltiorrhizae, Hirudo, Rhizoma Ligustici Chuanxiong, Rhizoma Gastrodiae, Fructus Crataegi, Stigma Croci, Herba Erigerontis, Semen Ginkgo, and Radix et Rhizoma Glycyrrhizae. The present disclosure treats the cardiovascular and cerebrovascular diseases through treatment based on syndrome differentiation and overall regulation in TCM; with less side effects, excellent efficacy, and fast acting, the present disclosure can achieve a stenting-free effect on the cardiovascular and cerebrovascular diseases.

Stenting-Free Pharmaceutical Composition for Treatment of Cardiovascular and Cerebrovascular Disease
20220362307 · 2022-11-17 ·

The present disclosure provides a traditional Chinese medicine (TCM) composition for the treatment of cardiovascular and cerebrovascular diseases and use thereof, and belongs to the technical field of TCM. The composition for the treatment of cardiovascular and cerebrovascular diseases provided by the present disclosure includes the following raw materials: Radix Panacis Quinquefolii, Pheretima, Radix et Rhizoma Salviae Miltiorrhizae, Hirudo, Rhizoma Ligustici Chuanxiong, Rhizoma Gastrodiae, Fructus Crataegi, Stigma Croci, Herba Erigerontis, Semen Ginkgo, and Radix et Rhizoma Glycyrrhizae. The present disclosure treats the cardiovascular and cerebrovascular diseases through treatment based on syndrome differentiation and overall regulation in TCM; with less side effects, excellent efficacy, and fast acting, the present disclosure can achieve a stenting-free effect on the cardiovascular and cerebrovascular diseases.