Provided is a pharmaceutical composition for preventing or treating inflammatory bowel disease (IBD) comprising a mixed extract of at least two of Aucklandia lappa Decne, Terminalia chebula Retzius, and Zingiber officinale Rosc. as an active ingredient and a method thereof, and more specifically, to a pharmaceutical composition having an inhibitory effect on monocyte adhesion in intestinal epithelial cells, an effect of inhibiting the production of inflammatory cytokines, an effect of ameliorating colitis in an animal model of dextran sodium sulfate (DSS)-induced colitis, and an effect of ameliorating Crohn's disease in an animal model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced Crohn's disease.

Provided is a pharmaceutical composition for preventing or treating inflammatory bowel disease (IBD) comprising a mixed extract of at least two of Aucklandia lappa Decne, Terminalia chebula Retzius, and Zingiber officinale Rosc. as an active ingredient and a method thereof, and more specifically, to a pharmaceutical composition having an inhibitory effect on monocyte adhesion in intestinal epithelial cells, an effect of inhibiting the production of inflammatory cytokines, an effect of ameliorating colitis in an animal model of dextran sodium sulfate (DSS)-induced colitis, and an effect of ameliorating Crohn's disease in an animal model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced Crohn's disease.

An anti-microbial composition includes an extract of at least one of Aucklandia lappa Decne and Punica granatum. The extract can be an aqueous ethanol extract. The extract can be formed using the peel of the pomegranate and the root of the Aucklandia lappa Decne. A weight ratio of the Aucklandia lappa Decne and Punica granatum in the composition can range from about 4:1 to about 1:1.

An anti-microbial composition includes an extract of at least one of Aucklandia lappa Decne and Punica granatum. The extract can be an aqueous ethanol extract. The extract can be formed using the peel of the pomegranate and the root of the Aucklandia lappa Decne. A weight ratio of the Aucklandia lappa Decne and Punica granatum in the composition can range from about 4:1 to about 1:1.

An anti-microbial composition includes an extract of at least one of Aucklandia lappa Decne and Punica granatum. The extract can be an aqueous ethanol extract. The extract can be formed using the peel of the pomegranate and the root of the Aucklandia lappa Decne. A weight ratio of the Aucklandia lappa Decne and Punica granatum in the composition can range from about 4:1 to about 1:1.

A therapeutic composition for wet and dry gangrene includes an herbal composition alone, or in combination with one or more animal-derived products. The herbal composition can include a mixture of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The mixture can include, for example, a mixture of extracts or whole herbs of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The one or more animal-derived products can include at least one of camel milk and camel saliva.

A therapeutic composition for wet and dry gangrene includes an herbal composition alone, or in combination with one or more animal-derived products. The herbal composition can include a mixture of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The mixture can include, for example, a mixture of extracts or whole herbs of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The one or more animal-derived products can include at least one of camel milk and camel saliva.

A therapeutic composition for wet and dry gangrene includes an herbal composition alone, or in combination with one or more animal-derived products. The herbal composition can include a mixture of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The mixture can include, for example, a mixture of extracts or whole herbs of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The one or more animal-derived products can include at least one of camel milk and camel saliva.

A therapeutic composition can include an herbal composition having solid material or liquid extracts from the solid material of at least one of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The solid material may include one or more of parts or the whole of the stem, the bark, the flowers and the roots of one or more, but preferably all of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The therapeutic composition can include camel milk, alone, or in combination with the herbal composition. The camel milk can be HIV-immunized camel milk. The HIV-immunized camel milk can be obtained by immunizing a camel against HIV by administering to the camel the modified DNA plasmids of SEQ. ID No.: 3 and SEQ ID No.: 4 and obtaining the milk from the immunized camel.

A therapeutic composition can include an herbal composition having solid material or liquid extracts from the solid material of at least one of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The solid material may include one or more of parts or the whole of the stem, the bark, the flowers and the roots of one or more, but preferably all of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The therapeutic composition can include camel milk, alone, or in combination with the herbal composition. The camel milk can be HIV-immunized camel milk. The HIV-immunized camel milk can be obtained by immunizing a camel against HIV by administering to the camel the modified DNA plasmids of SEQ. ID No.: 3 and SEQ ID No.: 4 and obtaining the milk from the immunized camel.