A61K36/287

Extract obtained from several plants for use in the prevention and/or treatment of chronic inflammatory bowel diseases

The invention relates to a composition comprising at least one specific mixture of molecules for use as a drug or nutritional product in the prevention and/or treatment of chronic inflammatory bowel diseases in humans or animals.

Prevention and Treatment of SARS-CoV-2 Infection by Mentha piperita and Flos chrysanthemi Extracts alone, and their Combination

Due to the SARS-CoV-2 pandemic, the development and screening of novel antiviral agents are urgently required. Herein, we developed herbal extracts with promising antiviral activity against SARS-CoV-2. Antiviral effects of Mentha piperita, and Flos chrysanthemi extracts alone, in combination and their fractions were found to decrease viral load. To determine which step of the virus is inhibited by the treatment, the extracts were administered at different time points of treatment, namely prophylactic (Full-time), pre-adsorption (Entry), and post adsorption (Post-entry). Most of the fractions, exhibited high efficacy upon prophylactic administration. The viral load was lower in prophylactic-treated cells than in non-treated cells. Administration of combinations, following 2:1 molar ratio of Mentha piperita, and Flos chrysanthemi significantly reduced the viral load by increasing the Cq values. Ethyl acetate extract of Mentha piperita and hexanes extract of Flos chrysanthemi were found to be most effective at all treatment points.

Prevention and Treatment of SARS-CoV-2 Infection by Mentha piperita and Flos chrysanthemi Extracts alone, and their Combination

Due to the SARS-CoV-2 pandemic, the development and screening of novel antiviral agents are urgently required. Herein, we developed herbal extracts with promising antiviral activity against SARS-CoV-2. Antiviral effects of Mentha piperita, and Flos chrysanthemi extracts alone, in combination and their fractions were found to decrease viral load. To determine which step of the virus is inhibited by the treatment, the extracts were administered at different time points of treatment, namely prophylactic (Full-time), pre-adsorption (Entry), and post adsorption (Post-entry). Most of the fractions, exhibited high efficacy upon prophylactic administration. The viral load was lower in prophylactic-treated cells than in non-treated cells. Administration of combinations, following 2:1 molar ratio of Mentha piperita, and Flos chrysanthemi significantly reduced the viral load by increasing the Cq values. Ethyl acetate extract of Mentha piperita and hexanes extract of Flos chrysanthemi were found to be most effective at all treatment points.

Prevention and Treatment of SARS-CoV-2 Infection by Mentha piperita and Flos chrysanthemi Extracts alone, and their Combination

Due to the SARS-CoV-2 pandemic, the development and screening of novel antiviral agents are urgently required. Herein, we developed herbal extracts with promising antiviral activity against SARS-CoV-2. Antiviral effects of Mentha piperita, and Flos chrysanthemi extracts alone, in combination and their fractions were found to decrease viral load. To determine which step of the virus is inhibited by the treatment, the extracts were administered at different time points of treatment, namely prophylactic (Full-time), pre-adsorption (Entry), and post adsorption (Post-entry). Most of the fractions, exhibited high efficacy upon prophylactic administration. The viral load was lower in prophylactic-treated cells than in non-treated cells. Administration of combinations, following 2:1 molar ratio of Mentha piperita, and Flos chrysanthemi significantly reduced the viral load by increasing the Cq values. Ethyl acetate extract of Mentha piperita and hexanes extract of Flos chrysanthemi were found to be most effective at all treatment points.

TRADITIONAL CHINESE MEDICINE COMPOSITION FOR TREATING TUMOURS, PREPARATION METHOD THEREFOR AND USE THEREOF
20210346452 · 2021-11-11 ·

Disclosed are a traditional Chinese medicine composition for treating tumours and a preparation method therefor, wherein the composition is prepared from Sophora flavescens, wild Chrysanthemum flower, honeysuckle, mint, Poria cocos, Atractylodes lancea, cinnamon, clove, Astragalus, Ganoderma lucidum, Ligusticum striatum, Aucklandia root and Radix glycyrrhizae. The traditional Chinese medicine composition has an anti-tumour effect.

TRADITIONAL CHINESE MEDICINE COMPOSITION FOR TREATING TUMOURS, PREPARATION METHOD THEREFOR AND USE THEREOF
20210346452 · 2021-11-11 ·

Disclosed are a traditional Chinese medicine composition for treating tumours and a preparation method therefor, wherein the composition is prepared from Sophora flavescens, wild Chrysanthemum flower, honeysuckle, mint, Poria cocos, Atractylodes lancea, cinnamon, clove, Astragalus, Ganoderma lucidum, Ligusticum striatum, Aucklandia root and Radix glycyrrhizae. The traditional Chinese medicine composition has an anti-tumour effect.

TRADITIONAL CHINESE MEDICINE COMPOSITION FOR TREATING TUMOURS, PREPARATION METHOD THEREFOR AND USE THEREOF
20210346452 · 2021-11-11 ·

Disclosed are a traditional Chinese medicine composition for treating tumours and a preparation method therefor, wherein the composition is prepared from Sophora flavescens, wild Chrysanthemum flower, honeysuckle, mint, Poria cocos, Atractylodes lancea, cinnamon, clove, Astragalus, Ganoderma lucidum, Ligusticum striatum, Aucklandia root and Radix glycyrrhizae. The traditional Chinese medicine composition has an anti-tumour effect.

COMPOSITIONS COMPRISING CBD FOR TREATING ANORECTAL DISORDERS
20220000796 · 2022-01-06 ·

The present invention discloses compositions comprising CBD and several herbal extracts and powders, and methods for the treatment of anorectal disorders such as hemorrhoids. In particular, the invention provides compositions useful in the treatment and alleviation of hemorrhoids and related symptoms

COMPOSITIONS COMPRISING CBD FOR TREATING ANORECTAL DISORDERS
20220000796 · 2022-01-06 ·

The present invention discloses compositions comprising CBD and several herbal extracts and powders, and methods for the treatment of anorectal disorders such as hemorrhoids. In particular, the invention provides compositions useful in the treatment and alleviation of hemorrhoids and related symptoms

COMPOSITIONS OF GINSENOSIDE RG3 AND GINSENOSIDE RG5 AND THEIR PHARMACEUTICAL USES INCLUDING ANTI-TUMOR EFFECTS
20230321125 · 2023-10-12 ·

In one aspect, a composition of ginsenoside Rg3 and ginsenoside Rg5 and a preparation method thereof, as well as its application in manufacturing drugs, foods and health products for boosting immunity, enhancing anti-tumor effects, improving resistance to anti-tumor targeted drugs, mitigating toxic and side effects of radiotherapy and chemotherapy or improving anti-fatigue effects. The composition has advantages in rapid action, less toxicity and side effects and is suitable for long-term use. In another aspect, a safe, highly efficient and stable drug, food or health product which can be obtained by a simple preparation process suitable for industrial production and which can be easily scaled up. In yet another aspect, a new type of components and production process for manufacturing drugs, foods and health products for boosting immunity, enhancing anti-tumor effect, improving resistance to anti-tumor targeted drugs, mitigating toxic and side effects of radiotherapy and chemotherapy or improving anti-fatigue effect.