Provided is a device suitable for direct topical administration of a pharmaceutical composition comprising at least one active component selected from the group consisting of cannabinoids, terpenes, flavonoids, CB1 receptor agonists, CB2 receptor agonists and combinations thereof to a region of the oral cavity of a subject and methods of use thereof. The device comprises a solid substrate having at least a portion configured and dimensioned to be contacted with the region of the oral cavity of the subject; and an amount of the pharmaceutical composition associated with at least a portion of the solid substrate, wherein the amount of pharmaceutical composition is at least partially releasable from the portion of solid substrate.

A method of treating or preventing postpartum blues or depression is described, comprising administering to a subject in need thereof: an antioxidant source; a tryptophan composition comprising from 1.0 g to 5.0 g of tryptophan; and a tyrosine composition comprising from 2.0 g to 50 g of tyrosine. The antioxidant source may comprise a food or an extract derived from such a food as grapes, berries such as blueberries, citrus fruit, pomegranate, tomato, squash, carrot, sweet potato, dark green vegetables, beets, leafy vegetables, Brassica oleracea vegetables, peppers, melons, pineapples, lentils, plant oils, and/or tree nuts.

A method of treating or preventing postpartum blues or depression is described, comprising administering to a subject in need thereof: an antioxidant source; a tryptophan composition comprising from 1.0 g to 5.0 g of tryptophan; and a tyrosine composition comprising from 2.0 g to 50 g of tyrosine. The antioxidant source may comprise a food or an extract derived from such a food as grapes, berries such as blueberries, citrus fruit, pomegranate, tomato, squash, carrot, sweet potato, dark green vegetables, beets, leafy vegetables, Brassica oleracea vegetables, peppers, melons, pineapples, lentils, plant oils, and/or tree nuts.

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory bowel disease, comprising an Isatidis folium extract. In addition, the present invention relates to a food composition or animal feed composition for preventing or improving inflammatory bowel disease, comprising the Isatidis folium extract.

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory bowel disease, comprising an Isatidis folium extract. In addition, the present invention relates to a food composition or animal feed composition for preventing or improving inflammatory bowel disease, comprising the Isatidis folium extract.

A composition for protecting liver, protecting intestines and enhancing immunity for freshwater fish is disclosed, including the following raw materials in parts by weight: 1527 parts of Andrographis herba, 1822 parts of Isatidis folium, 1015 parts of Polygonum hydropiper, 812 parts of Rheum palmatum L., and 812 parts of Galla chinensis. And the preparation and the application of the composition are disclosed. The composition of the disclosure has the effect of resisting bacteria, scavenge free radicals, clearing heat, detoxifying, preventing and treating enteritis and the like, which can effectively improve the immunity of the freshwater fish and ensure the health of the organism.

A composition for protecting liver, protecting intestines and enhancing immunity for freshwater fish is disclosed, including the following raw materials in parts by weight: 1527 parts of Andrographis herba, 1822 parts of Isatidis folium, 1015 parts of Polygonum hydropiper, 812 parts of Rheum palmatum L., and 812 parts of Galla chinensis. And the preparation and the application of the composition are disclosed. The composition of the disclosure has the effect of resisting bacteria, scavenge free radicals, clearing heat, detoxifying, preventing and treating enteritis and the like, which can effectively improve the immunity of the freshwater fish and ensure the health of the organism.

The solution provides a method for separating a Chinese traditional medicine composition. To explain a pharmacological effect mechanism of a medicine made of two or more components and scientific content in rules of compatibility among components of a compound medicine, systematic researches on the material basis is very necessary. Accordingly, deep researches are done on chemical components of the pharmaceutical composition in the solution, and eight compounds are separated, which are 10-O-(p-hydroxycinnamoyl)-adoxosidic acid, aloe-emodin-8-O--D-glucopyranoside, quercitrin, matairesinol-4-O-glucoside, liquiritin apioside, epi-vogeloside, vogeloside and ethyl caffeate, which provides a new quality control method for the composition in the solution.

The solution provides a method for separating a Chinese traditional medicine composition. To explain a pharmacological effect mechanism of a medicine made of two or more components and scientific content in rules of compatibility among components of a compound medicine, systematic researches on the material basis is very necessary. Accordingly, deep researches are done on chemical components of the pharmaceutical composition in the solution, and eight compounds are separated, which are 10-O-(p-hydroxycinnamoyl)-adoxosidic acid, aloe-emodin-8-O--D-glucopyranoside, quercitrin, matairesinol-4-O-glucoside, liquiritin apioside, epi-vogeloside, vogeloside and ethyl caffeate, which provides a new quality control method for the composition in the solution.

Kits for the treatment or prophylaxis of depressed mood are described, for subjects with increased MAO-A levels, excessive crying, or subjects within or beyond the 5-day postpartum period. The kits are used to implement a method by which the subject is administered an antioxidant source on at least the first day of a 3 to 5 day regime; a tryptophan composition on the evening of the penultimate treatment day, simultaneously or following the antioxidant source; and a tyrosine composition the day after the tryptophan composition, on the final treatment day. The kit comprises an antioxidant source which may comprise or be derived from blueberries. Individuals with depressed mood due to perimenopause, alcohol use disorders or withdrawal, or who are up to or beyond 18-months postpartum, may benefit from the kits. The kits described may reduce the likelihood of advancing from depressed mood to depression.