A gynostemma pentaphyllum-containing health care pharmaceutical composition for preventing hyperlipidemia, hypertension, hyperglycemia and gout is prepared by mixing raw materials of gynostemma pentaphyllum, folium eucommiae, folium mori, semen plantaginis, herba lophatheri, pueraria mirifica powder, pelargonium graveolens and sanguisorba minor, and the raw materials are in percentage by mass: 40-70% of gynostemma pentaphyllum, 5-20% of folium eucommiae, 5-20% of folium mori, 5-10% of semen plantaginis, 2-10% of herba lophatheri, 2-10% of pueraria mirifica powder, 2-8% of pelargonium graveolens and 2-8% of sanguisorba minor. The gynostemma pentaphyllum is prepared by mixing diploid gynostemma pentaphyllum leaves and tetraploid gynostemma pentaphyllum leaves according to a ratio. The pharmaceutical composition is mainly aimed at people who suffer from hyperlipidemia, hypertension, hyperglycemia and hyperuricemia, and used for preventing and treating the four hypers

A gynostemma pentaphyllum-containing health care pharmaceutical composition for preventing hyperlipidemia, hypertension, hyperglycemia and gout is prepared by mixing raw materials of gynostemma pentaphyllum, folium eucommiae, folium mori, semen plantaginis, herba lophatheri, pueraria mirifica powder, pelargonium graveolens and sanguisorba minor, and the raw materials are in percentage by mass: 40-70% of gynostemma pentaphyllum, 5-20% of folium eucommiae, 5-20% of folium mori, 5-10% of semen plantaginis, 2-10% of herba lophatheri, 2-10% of pueraria mirifica powder, 2-8% of pelargonium graveolens and 2-8% of sanguisorba minor. The gynostemma pentaphyllum is prepared by mixing diploid gynostemma pentaphyllum leaves and tetraploid gynostemma pentaphyllum leaves according to a ratio. The pharmaceutical composition is mainly aimed at people who suffer from hyperlipidemia, hypertension, hyperglycemia and hyperuricemia, and used for preventing and treating the four hypers

A method for preparing an extract of fermented Gynostemma pentaphyllum with increased contents of saponins or low-molecular-weight saponins, which includes a step of preparing a Gynostemma pentaphyllum fermentation product by fermenting Gynostemma pentaphyllum with a microorganism selected from Aspergillus oryzae, Aspergillus awamori, Aspergillus kawachii, Lactobacillus brevis and Lactobacillus plantarum; and a step of extracting the Gynostemma pentaphyllum fermentation product with hot water.

A method for preparing an extract of fermented Gynostemma pentaphyllum with increased contents of saponins or low-molecular-weight saponins, which includes a step of preparing a Gynostemma pentaphyllum fermentation product by fermenting Gynostemma pentaphyllum with a microorganism selected from Aspergillus oryzae, Aspergillus awamori, Aspergillus kawachii, Lactobacillus brevis and Lactobacillus plantarum; and a step of extracting the Gynostemma pentaphyllum fermentation product with hot water.

The present invention provides novel compositions for suppressing or improving hair loss, and compositions for suppressing or improving graying. More specifically, it provides agents that stabilize type XVII collagen expression, preferably agents that suppress the degradation of type XVII collagen by ELANE inhibitors and such, and compositions comprising a DNA repair-promoting agent or a DNA damage-suppressing agent as an active ingredient. Advantageous suppressive effects of hair loss and graying can be obtained when a composition comprising as an active ingredient a suppressive agent of type XVII collagen degradation such as an ELANE inhibitor is administered to a mammal. For the ELANE inhibitors, suppressive agents of type XVII collagen degradation and DNA repair-promoting agents, low-molecular compounds, polypeptides, proteins, antibodies, or nucleic acid medicine such as antisense oligos or siRNAs may be used. A method of screening for effective substances for suppression of hair loss and graying is also provided.

A beverage for supplemental health; the beverage for supplemental health includes adaptogen herb tinctures, at least one flavoring agent, vitamins, minerals, at least one preservative and carbonated water. The beverage for supplemental health is useful for improving the overall health and wellness of an individual. The beverage for supplemental health is an admixture to promote health.

A beverage for supplemental health; the beverage for supplemental health includes adaptogen herb tinctures, at least one flavoring agent, vitamins, minerals, at least one preservative and carbonated water. The beverage for supplemental health is useful for improving the overall health and wellness of an individual. The beverage for supplemental health is an admixture to promote health.

A beverage for supplemental health; the beverage for supplemental health includes adaptogen herb tinctures, at least one flavoring agent, vitamins, minerals, at least one preservative and carbonated water. The beverage for supplemental health is useful for improving the overall health and wellness of an individual. The beverage for supplemental health is an admixture to promote health.

A method of preventing or treating an inflammatory disease and/or conditions associated with inflammation and/or biomarkers associated with inflammation in a subject in need thereof is provided. Also provided are pharmaceutical compositions, articles and foods for the treatment of an inflammatory disease using natural active compounds such as herb and flower extracts.

A method of preventing or treating an inflammatory disease and/or conditions associated with inflammation and/or biomarkers associated with inflammation in a subject in need thereof is provided. Also provided are pharmaceutical compositions, articles and foods for the treatment of an inflammatory disease using natural active compounds such as herb and flower extracts.