A61K36/481

DRUG FOR TREATING LEUKOPENIA, PREPARATION METHOD THEREOF AND USE THEREOF
20210379138 · 2021-12-09 ·

The present invention relates to a drug for treating leukopenia, its preparation method and use thereof. The drug of the invention is prepared from 200-30 parts by weight of Folium Epimedii, 100-160 parts by weight of Fructus Psoraleae, 60-120 parts by weight of Radix Aconiti Lateralis Preparata (Processed), 200-300 parts by weight of Fructus Lycii, 200-300 parts by weight of Radix Astragali, 200-300 parts by weight of Caulis Spatholobi, 200-300 parts by weight of Radix Rubiae, 100-160 parts by weight of Radix Angelicae Sinensis, 200-300 parts by weight of Rhizoma Phragmitis, 100-160 parts by weight of Radix Ophiopogonis and 100-160 parts by weight of Radix et Rhizoma Glycyrrhizae. The drug of the invention comprises chemical substances with weight ratios as follows: Leucine:guanosine:psoralenoside:isopsoralenoside:calycosin-7-glucoside:liquiritin:icariin A:1,3-dihydroxyl-2-hydroxymethylanthraquinone:epimedin A:epimedin B:epimedin C:icariin:1,3,6-trihydroxy-2-methylanthraquinone:glycyrrhizic acid=(0.13-0.27):(0.04-0.11):(0.11-0.34):(0.09-0.34):(0.05-0.11):(0.16-0.26):(0.09-0.12):(0.17-0.35):(0.11-0.16):(0.17-0.26):(0.49-0.59):1.00:(0.16-0.24):(0.08-0.14).

DRUG FOR TREATING LEUKOPENIA, PREPARATION METHOD THEREOF AND USE THEREOF
20210379138 · 2021-12-09 ·

The present invention relates to a drug for treating leukopenia, its preparation method and use thereof. The drug of the invention is prepared from 200-30 parts by weight of Folium Epimedii, 100-160 parts by weight of Fructus Psoraleae, 60-120 parts by weight of Radix Aconiti Lateralis Preparata (Processed), 200-300 parts by weight of Fructus Lycii, 200-300 parts by weight of Radix Astragali, 200-300 parts by weight of Caulis Spatholobi, 200-300 parts by weight of Radix Rubiae, 100-160 parts by weight of Radix Angelicae Sinensis, 200-300 parts by weight of Rhizoma Phragmitis, 100-160 parts by weight of Radix Ophiopogonis and 100-160 parts by weight of Radix et Rhizoma Glycyrrhizae. The drug of the invention comprises chemical substances with weight ratios as follows: Leucine:guanosine:psoralenoside:isopsoralenoside:calycosin-7-glucoside:liquiritin:icariin A:1,3-dihydroxyl-2-hydroxymethylanthraquinone:epimedin A:epimedin B:epimedin C:icariin:1,3,6-trihydroxy-2-methylanthraquinone:glycyrrhizic acid=(0.13-0.27):(0.04-0.11):(0.11-0.34):(0.09-0.34):(0.05-0.11):(0.16-0.26):(0.09-0.12):(0.17-0.35):(0.11-0.16):(0.17-0.26):(0.49-0.59):1.00:(0.16-0.24):(0.08-0.14).

Method for preparing granules or pills containing extracts in high concentration

The present invention relates to a method for preparing a granule or a pill containing a plant, medicinal herb or traditional oriental medicine decoction extract, having the steps of: (a) injecting a powdered plant, medicinal herb or traditional oriental medicine decoction extract into a fluidized-bed device and spraying purified water or a solution of the same type of extract as the extract powder at the extract powder while fluidizing the same, thereby generating microgranules of the extract powder; and (b) injecting the microgranules generated at step (a) as seeds into the fluidized-bed device and spraying a solution of the extract while fluidizing the same, thereby growing the microgranules to a predetermined size of granule or pill. According to the present invention, it is possible to prepare a granule or a pill containing an extract in a high concentration.

Method for preparing granules or pills containing extracts in high concentration

The present invention relates to a method for preparing a granule or a pill containing a plant, medicinal herb or traditional oriental medicine decoction extract, having the steps of: (a) injecting a powdered plant, medicinal herb or traditional oriental medicine decoction extract into a fluidized-bed device and spraying purified water or a solution of the same type of extract as the extract powder at the extract powder while fluidizing the same, thereby generating microgranules of the extract powder; and (b) injecting the microgranules generated at step (a) as seeds into the fluidized-bed device and spraying a solution of the extract while fluidizing the same, thereby growing the microgranules to a predetermined size of granule or pill. According to the present invention, it is possible to prepare a granule or a pill containing an extract in a high concentration.

HEALTH MANAGEMENT COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF
20210369674 · 2021-12-02 ·

The nutraceutical composition includes a neuroprotecting composition, an anti-inflammatory composition, a cardiovascular protecting composition, an antioxidant composition, and a gelling component in a sufficient amount to provide a cohesive gelled product.

HEALTH MANAGEMENT COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF
20210369674 · 2021-12-02 ·

The nutraceutical composition includes a neuroprotecting composition, an anti-inflammatory composition, a cardiovascular protecting composition, an antioxidant composition, and a gelling component in a sufficient amount to provide a cohesive gelled product.

PRODUCTION METHOD OF TELOMERASE ACTIVATORS AND TELOMERASE ACTIVATORS OBTAINED BY THIS METHOD

A method for producing telomerase activators which provide to obtain new/novel molecules (metabolites) from saponin group compounds by using biotransformation with endophytic fungi and telomerase activators obtained by this method. Included is the elucidation of chemical structures and investigation of the effects of telomerase enzyme activation in cells. These molecules have the potential to be used in diseases and/or conditions that can be treated/ameliorated by telomerase activation and associated with telomere shortening (For example; HIV, degenerative diseases, acute and chronic wound healing, ex vivo cell therapies and stem cell proliferation due to increment in vitro and ex-vivo replicative capacity of cells).

PRODUCTION METHOD OF TELOMERASE ACTIVATORS AND TELOMERASE ACTIVATORS OBTAINED BY THIS METHOD

A method for producing telomerase activators which provide to obtain new/novel molecules (metabolites) from saponin group compounds by using biotransformation with endophytic fungi and telomerase activators obtained by this method. Included is the elucidation of chemical structures and investigation of the effects of telomerase enzyme activation in cells. These molecules have the potential to be used in diseases and/or conditions that can be treated/ameliorated by telomerase activation and associated with telomere shortening (For example; HIV, degenerative diseases, acute and chronic wound healing, ex vivo cell therapies and stem cell proliferation due to increment in vitro and ex-vivo replicative capacity of cells).

TRADITIONAL CHINESE MEDICINE COMPOUND COMPOSITION WITH IMMUNE BIDIRECTIONAL REGULATION EFFECT AND PREPARATION METHOD AND APPLICATIONS THEREOF

A traditional Chinese medicine compound composition with immune bidirectional regulation effect and its preparation method and applications are disclosed. The traditional Chinese medicine compound composition with immune bidirectional regulation effect is prepared by compounding a volatile oil obtained after heating and refluxing of Schizonepetae herba and an extract jointly extracted by Schizonepetae herba extract residue, Astragali radix and Atractylodes macrocephala in the disclosure. The traditional Chinese medicine compound composition has no side effects and remarkable effect, and the traditional Chinese medicine compound composition disclosed by the disclosure can be used as a dietary supplement or health food raw material to regulate allergic reaction and low immunity. The traditional Chinese medicine compound composition disclosed by the disclosure is suitable for promotion and application.

TRADITIONAL CHINESE MEDICINE COMPOUND COMPOSITION WITH IMMUNE BIDIRECTIONAL REGULATION EFFECT AND PREPARATION METHOD AND APPLICATIONS THEREOF

A traditional Chinese medicine compound composition with immune bidirectional regulation effect and its preparation method and applications are disclosed. The traditional Chinese medicine compound composition with immune bidirectional regulation effect is prepared by compounding a volatile oil obtained after heating and refluxing of Schizonepetae herba and an extract jointly extracted by Schizonepetae herba extract residue, Astragali radix and Atractylodes macrocephala in the disclosure. The traditional Chinese medicine compound composition has no side effects and remarkable effect, and the traditional Chinese medicine compound composition disclosed by the disclosure can be used as a dietary supplement or health food raw material to regulate allergic reaction and low immunity. The traditional Chinese medicine compound composition disclosed by the disclosure is suitable for promotion and application.