An anti-tumor traditional Chinese medicine, a preparation method therefor, and uses thereof. This traditional Chinese medicine is prepared by leavening of Pleurotus sp. and dioscorea bulbifera, pangolin scales, rhubarb, oyster, stiff silkworm, kelp, selfheal, ligusticum wallichii, barbat skullcap, honeysuckle flower, oldenlandia diffusa, radix trichosanthis, rhizoma anemarrhenae scutellaria baicalensis, angelica sinensis psoralea corylifolia, lucid ganoderma, and coix seed.

An anti-tumor traditional Chinese medicine, a preparation method therefor, and uses thereof. This traditional Chinese medicine is prepared by leavening of Pleurotus sp. and dioscorea bulbifera, pangolin scales, rhubarb, oyster, stiff silkworm, kelp, selfheal, ligusticum wallichii, barbat skullcap, honeysuckle flower, oldenlandia diffusa, radix trichosanthis, rhizoma anemarrhenae scutellaria baicalensis, angelica sinensis psoralea corylifolia, lucid ganoderma, and coix seed.

Disclosed herein are an anti-obesity agent from natural products based on angiogenesis inhibitory actions, and an angiogenesis inhibitor or a composition for inhibiting obesity, containing at least one selected from the group consisting of Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract. Because the Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract of the present invention exhibit angiogenesis inhibitory effects and obesity inhibitory effects, they may be usefully used as an agent for prevention and treatment of angiogenesis-related diseases or obesity.

Disclosed herein are an anti-obesity agent from natural products based on angiogenesis inhibitory actions, and an angiogenesis inhibitor or a composition for inhibiting obesity, containing at least one selected from the group consisting of Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract. Because the Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract of the present invention exhibit angiogenesis inhibitory effects and obesity inhibitory effects, they may be usefully used as an agent for prevention and treatment of angiogenesis-related diseases or obesity.

Disclosed herein are an anti-obesity agent from natural products based on angiogenesis inhibitory actions, and an angiogenesis inhibitor or a composition for inhibiting obesity, containing at least one selected from the group consisting of Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract. Because the Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract of the present invention exhibit angiogenesis inhibitory effects and obesity inhibitory effects, they may be usefully used as an agent for prevention and treatment of angiogenesis-related diseases or obesity.

A method for activating mammalian SIRT1 in a cell comprising:

providing a compound of formula (1):

##STR00001##

and incubating the cell with the compound. Also provided is a method for extending life span of a subject comprising: providing the same compound; and administering the compound to the subject. Yet also provided is a method for treating a mammalian SIRT1 inactivation-related disease in a subject comprising: providing the same compound; and administering the compound to the subject.

A method for activating mammalian SIRT1 in a cell comprising:

providing a compound of formula (1):

##STR00001##

and incubating the cell with the compound. Also provided is a method for extending life span of a subject comprising: providing the same compound; and administering the compound to the subject. Yet also provided is a method for treating a mammalian SIRT1 inactivation-related disease in a subject comprising: providing the same compound; and administering the compound to the subject.

The composition includes the following active components: component (1): at least one kind of honey-fried licorice root, licorice root, Dioscorea japonica Thunberg, jujube fruit, malt starch syrup, and ginseng root; component (2): at least one of wild turmeric, longan aril, zedoary root, Suberect Spatholobus stem, Luffa vegetable sponge, Sparganium rhizome, safflower, and Artemisia anomala; component (3): at least one of tea leaf, mentha herb, mulberry leaf, chrysanthemum flower, and Koushi; and component (4): at least two of ripe tangerine peel, Psoralea corylifolia fruit, Chaenomeles speciosa fruit, Piper longum, cinnamon twig, Perilla, ginger root, coriander, Allium fistulosum Linne, Zizyphi Spinosi Semen, Chinese arborvitae kernel, plantago seed, plantago herb, coix seed, corn silk, belvedere Fruit, Benincasa seed, knotgrass, snowbellleaf tickclover herb, cinnamon, processed ginger, fennel, Zanthoxylum fruit, Piper nigrum, Eleutherococcus senticosus Rhizome, and Artemisia leaf.

The composition includes the following active components: component (1): at least one kind of honey-fried licorice root, licorice root, Dioscorea japonica Thunberg, jujube fruit, malt starch syrup, and ginseng root; component (2): at least one of wild turmeric, longan aril, zedoary root, Suberect Spatholobus stem, Luffa vegetable sponge, Sparganium rhizome, safflower, and Artemisia anomala; component (3): at least one of tea leaf, mentha herb, mulberry leaf, chrysanthemum flower, and Koushi; and component (4): at least two of ripe tangerine peel, Psoralea corylifolia fruit, Chaenomeles speciosa fruit, Piper longum, cinnamon twig, Perilla, ginger root, coriander, Allium fistulosum Linne, Zizyphi Spinosi Semen, Chinese arborvitae kernel, plantago seed, plantago herb, coix seed, corn silk, belvedere Fruit, Benincasa seed, knotgrass, snowbellleaf tickclover herb, cinnamon, processed ginger, fennel, Zanthoxylum fruit, Piper nigrum, Eleutherococcus senticosus Rhizome, and Artemisia leaf.

A composition for the treatment of acne includes hydrolyzed Psoralea corylifolia, containing a component bakuchiol, is solubilized in a water-based solution. The composition is for topical application to the skin. In various implementations, the composition is a water-based acne gel or a water-based cleanser. In a specific implementation, a composition includes Bakutrol, which includes bakuchiol, and bisabolol. The composition can include a polysorbate surfactant. In implementations, these ingredients are combined with other active ingredients, including for example, salicylic acid, benzoyl peroxide, tretinoin, retinol, tazarotene, or an antibiotic, or a combination of these. A process of preparation of the composition allows for the stabilization of Bakutrol in solution.