The present invention pertains to: the provision of a method for promoting skin wound healing and a composition to be used for promoting skin wound healing; the provision of a method useful for preventing or ameliorating ulcers and bedsores or a composition therefor; the provision of a method for preventing skin aging and a composition to be used for preventing skin aging; the provision of a composition useful for preventing or ameliorating skin damage caused by an anticancer agent; and, furthermore, the provision of a method for enhancing the regeneration ability of epidermal stem cells and a composition for enhancing the regeneration ability of epidermal stem cells. More specifically, use of a composition, said composition being characterized by comprising, as an active ingredient, a substance selected from the group consisting of a substance which induces or maintains the expression of COL17A1 in cells, a substance which inhibits the degradation of COL17A1 in cells, a substance which promotes the competitive amplification ability of epidermal stem cells, a substance which suppresses genomic stress or oxidative stress in cells and a substance which prevents DNA damage in cells, enables the promotion of skin wound healing, protection from an anticancer agent and prevention of skin aging. Thus, the regeneration ability of epidermal stem cells can be enhanced.

A traditional Chinese medicine composition for treating dermatophytosis and bromhidrosis, which is prepared from radix sophorae flavescentis and peristrophe japonica, has synergistic interaction and anti-fungal effects, and is not easy to produce drug tolerance. After performing compatibility of extracts of matrine and peristrophe japonica, dermatophytosis and bromhidrosis can be treated, and multiple external preparations can be prepared.

A traditional Chinese medicine composition for treating dermatophytosis and bromhidrosis, which is prepared from radix sophorae flavescentis and peristrophe japonica, has synergistic interaction and anti-fungal effects, and is not easy to produce drug tolerance. After performing compatibility of extracts of matrine and peristrophe japonica, dermatophytosis and bromhidrosis can be treated, and multiple external preparations can be prepared.

A traditional Chinese medicine composition for treating dermatophytosis and bromhidrosis, which is prepared from radix sophorae flavescentis and peristrophe japonica, has synergistic interaction and anti-fungal effects, and is not easy to produce drug tolerance. After performing compatibility of extracts of matrine and peristrophe japonica, dermatophytosis and bromhidrosis can be treated, and multiple external preparations can be prepared.

The present invention relates to a pharmaceutical composition for treating climacteric disorder, containing Lactobacillus gasseri BNR17 as an active ingredient, and a functional food composition for preventing or ameliorating climacteric symptoms, containing Lactobacillus gasseri BNR17 as an active ingredient. Lactobacillus gasseri BNR17 according to the present invention has an excellent effect of treating, preventing, or ameliorating various climacteric symptoms, such as amelioration of osteoporosis, which is the representative symptom of climacterium, amelioration of involutional depression, amelioration of pain hypersensitivity, and amelioration of vaginal dryness.

The present invention relates to a pharmaceutical composition for treating climacteric disorder, containing Lactobacillus gasseri BNR17 as an active ingredient, and a functional food composition for preventing or ameliorating climacteric symptoms, containing Lactobacillus gasseri BNR17 as an active ingredient. Lactobacillus gasseri BNR17 according to the present invention has an excellent effect of treating, preventing, or ameliorating various climacteric symptoms, such as amelioration of osteoporosis, which is the representative symptom of climacterium, amelioration of involutional depression, amelioration of pain hypersensitivity, and amelioration of vaginal dryness.

The present invention relates to a pharmaceutical composition for treating climacteric disorder, containing Lactobacillus gasseri BNR17 as an active ingredient, and a functional food composition for preventing or ameliorating climacteric symptoms, containing Lactobacillus gasseri BNR17 as an active ingredient. Lactobacillus gasseri BNR17 according to the present invention has an excellent effect of treating, preventing, or ameliorating various climacteric symptoms, such as amelioration of osteoporosis, which is the representative symptom of climacterium, amelioration of involutional depression, amelioration of pain hypersensitivity, and amelioration of vaginal dryness.

Compositions for topical use and having a melanin synthesis-inhibiting activity that include an amount of a botanical extract of at least one of Aspalathus Linearis, Matricaria, Saxifraga, Astragalus, Taraxacum officinale/mongolicum, Ferula varia/foetida, Carthamus tinctorius, Sophora flavescentis, or Chrysanthemum morifolium effective to reduce melanin synthesis are described. Methods for inhibiting melanin synthesis and for skin whitening are also described.

Compositions for topical use and having a melanin synthesis-inhibiting activity that include an amount of a botanical extract of at least one of Aspalathus Linearis, Matricaria, Saxifraga, Astragalus, Taraxacum officinale/mongolicum, Ferula varia/foetida, Carthamus tinctorius, Sophora flavescentis, or Chrysanthemum morifolium effective to reduce melanin synthesis are described. Methods for inhibiting melanin synthesis and for skin whitening are also described.

Compositions for topical use and having a melanin synthesis-inhibiting activity that include an amount of a botanical extract of at least one of Aspalathus Linearis, Matricaria, Saxifraga, Astragalus, Taraxacum officinale/mongolicum, Ferula varia/foetida, Carthamus tinctorius, Sophora flavescentis, or Chrysanthemum morifolium effective to reduce melanin synthesis are described. Methods for inhibiting melanin synthesis and for skin whitening are also described.