The present invention relates to an anti-inflammatory composition and a composition for treatment of an inflammatory disease, both comprising a composite plant extract and, more particularly, to an anti-inflammatory composition comprising a composite plant extract including a Perilla frutescens extract and an Atractylodes macrocephala Koidzumi extract; a preparation method thereof; and a pharmaceutical composition comprising the composite extract for treatment of an inflammatory disease.

Disclosed herein is a method against coronavirus infection, which includes administering to a subject in need thereof a composition containing a water-extracted product of Perilla frutescens.

Disclosed herein is a method against coronavirus infection, which includes administering to a subject in need thereof a composition containing a water-extracted product of Perilla frutescens.

The present invention relates to a nasal composition comprising an anti-allergic oil derived from plant; and an oil-based barrier-forming preparation. The composition may be used in preventing and/or treating allergic disorders of the nasal cavity, including seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis.

The present invention relates to a nasal composition comprising an anti-allergic oil derived from plant; and an oil-based barrier-forming preparation. The composition may be used in preventing and/or treating allergic disorders of the nasal cavity, including seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis.

The present invention relates to a nasal composition comprising an anti-allergic oil derived from plant; and an oil-based barrier-forming preparation. The composition may be used in preventing and/or treating allergic disorders of the nasal cavity, including seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis.

A food contains a vitamin D.sub.2 mushroom oil. A content of vitamin D.sub.2 in unit dose of the food is not less than 0.5 μg. The vitamin D.sub.2 mushroom oil has a peroxide value less than or equal to 15 meq/kg and an acid value less than or equal to 3 mg/g. The vitamin D.sub.2 mushroom oil is prepared through a step of subjecting a vitamin D.sub.2-containing mushroom powder to extraction with an edible oil. The food contains a nutrient selected from the group consisting of perilla oil, walnut oil, linseed oil, peanut oil, olive oil, arachidonic acid (ARA), docosahexaenoic acid (DHA), vitamin A, calcium alginate and a combination thereof.

A food contains a vitamin D.sub.2 mushroom oil. A content of vitamin D.sub.2 in unit dose of the food is not less than 0.5 μg. The vitamin D.sub.2 mushroom oil has a peroxide value less than or equal to 15 meq/kg and an acid value less than or equal to 3 mg/g. The vitamin D.sub.2 mushroom oil is prepared through a step of subjecting a vitamin D.sub.2-containing mushroom powder to extraction with an edible oil. The food contains a nutrient selected from the group consisting of perilla oil, walnut oil, linseed oil, peanut oil, olive oil, arachidonic acid (ARA), docosahexaenoic acid (DHA), vitamin A, calcium alginate and a combination thereof.

The present invention, it was confirmed that a pharmaceutical composition and a health functional food composition for alleviating eye fatigue containing, as active ingredients, compounds, particularly, luteolin-7-O-diglucuronide and apigenin-7-O-diglucuronide isolated from a Perilla frutescens (L.) Britton var. acuta (Thunb.) Kudo leaf extract have an effect of alleviating eye fatigue by increasing the contents of NO and cGMP associated with relaxation of ciliary smooth muscle cells isolated from rat's eyes and decreasing the content of [Ca.sup.2+]i, and increasing cGMP which is a factor associated with relaxation of the ciliary smooth muscle through an animal experiment. As a result, the luteolin-7-O-diglucuronide and apigenin-7-O-diglucuronide compounds extracted from Perilla frutescens (L.) Britton var. acuta (Thunb.) Kudo may be usefully used as a pharmaceutical composition and a health functional food composition having an eye fatigue alleviating effect as a Korean natural resource.

The present invention, it was confirmed that a pharmaceutical composition and a health functional food composition for alleviating eye fatigue containing, as active ingredients, compounds, particularly, luteolin-7-O-diglucuronide and apigenin-7-O-diglucuronide isolated from a Perilla frutescens (L.) Britton var. acuta (Thunb.) Kudo leaf extract have an effect of alleviating eye fatigue by increasing the contents of NO and cGMP associated with relaxation of ciliary smooth muscle cells isolated from rat's eyes and decreasing the content of [Ca.sup.2+]i, and increasing cGMP which is a factor associated with relaxation of the ciliary smooth muscle through an animal experiment. As a result, the luteolin-7-O-diglucuronide and apigenin-7-O-diglucuronide compounds extracted from Perilla frutescens (L.) Britton var. acuta (Thunb.) Kudo may be usefully used as a pharmaceutical composition and a health functional food composition having an eye fatigue alleviating effect as a Korean natural resource.