A61K36/634

ANTICANCER AGENT, RADIOSENSITIZER, AND FOOD COMPOSITION

Provided are an anticancer agent, radiosensitizer, and food composition capable of enhancing the effects of radiation therapy. The present inventors discovered that tumors shrink significantly in comparison to an untreated group and the respective monotherapy groups when treatment by burdock fruit extract containing arctigenin and radiation therapy were used in combination on mice transplanted with human pancreatic cancer cells. The anticancer agent of the present invention is an anticancer agent containing arctigenin and/or arctiin as the active ingredient, to be used in combination with radiation therapy. The arctigenin and/or arctiin may be contained as burdock, burdock fruit, burdock sprout, or forsythia, or an extract extracted from these.

ANTICANCER AGENT, RADIOSENSITIZER, AND FOOD COMPOSITION

Provided are an anticancer agent, radiosensitizer, and food composition capable of enhancing the effects of radiation therapy. The present inventors discovered that tumors shrink significantly in comparison to an untreated group and the respective monotherapy groups when treatment by burdock fruit extract containing arctigenin and radiation therapy were used in combination on mice transplanted with human pancreatic cancer cells. The anticancer agent of the present invention is an anticancer agent containing arctigenin and/or arctiin as the active ingredient, to be used in combination with radiation therapy. The arctigenin and/or arctiin may be contained as burdock, burdock fruit, burdock sprout, or forsythia, or an extract extracted from these.

BILE ACID SYNTHESIS PROMOTER, COMPOSITION FOR PROMOTING BILE ACID SYNTHESIS AND FOOD COMPOSITION FOR PROMOTING BILE ACID SYNTHESIS

[Problem] To provide a novel medicine that is capable of promoting cholesterol metabolism to thereby treat, ameliorate or prevent various symptoms associated with increase in blood cholesterol level. [Solution] The present inventors newly found that arctigenin has an effect of promoting the conversio n of cholesterol into bile acid. The present invention provides a bile acid synthesis promoter, a composition for promoting bile acid synthesis and a food composition for promoting bile acid synthesis each comprising arctigenin and/or arctiin as active ingredient(s).

Device for herbal medicine in which release of medicinal ingredient can be controlled, and manufacturing method thereof
10980752 · 2021-04-20 · ·

The present disclosure relates to a method for manufacturing a device for herbal medicine in which the airborne release of medicinal ingredients can be controlled, which comprises: separating two or more medicinal herbal ingredients prescribed or prepared according to pharmacological effects on the basis of the weight ratio of each medicinal ingredient to total weight of the medicinal ingredients; grinding the medicinal ingredients separated on the basis of weight ratio, wherein fine particles are ground to different sizes according to the setting of release duration; preparing herbal medicine by mixing the ground medicinal ingredients together, and then mixing the ingredients with a binding agent; and adhering the herbal medicine to a base sheet. The device for herbal medicine manufactured according to the method allows for persistent permeation of medical ingredients through mucous membrane with different release rate for each medicinal ingredient, and thus, the efficacy of the medicinal ingredient layer and the effect of treating disease can be maximized.

Device for herbal medicine in which release of medicinal ingredient can be controlled, and manufacturing method thereof
10980752 · 2021-04-20 · ·

The present disclosure relates to a method for manufacturing a device for herbal medicine in which the airborne release of medicinal ingredients can be controlled, which comprises: separating two or more medicinal herbal ingredients prescribed or prepared according to pharmacological effects on the basis of the weight ratio of each medicinal ingredient to total weight of the medicinal ingredients; grinding the medicinal ingredients separated on the basis of weight ratio, wherein fine particles are ground to different sizes according to the setting of release duration; preparing herbal medicine by mixing the ground medicinal ingredients together, and then mixing the ingredients with a binding agent; and adhering the herbal medicine to a base sheet. The device for herbal medicine manufactured according to the method allows for persistent permeation of medical ingredients through mucous membrane with different release rate for each medicinal ingredient, and thus, the efficacy of the medicinal ingredient layer and the effect of treating disease can be maximized.

Device for herbal medicine in which release of medicinal ingredient can be controlled, and manufacturing method thereof
10980752 · 2021-04-20 · ·

The present disclosure relates to a method for manufacturing a device for herbal medicine in which the airborne release of medicinal ingredients can be controlled, which comprises: separating two or more medicinal herbal ingredients prescribed or prepared according to pharmacological effects on the basis of the weight ratio of each medicinal ingredient to total weight of the medicinal ingredients; grinding the medicinal ingredients separated on the basis of weight ratio, wherein fine particles are ground to different sizes according to the setting of release duration; preparing herbal medicine by mixing the ground medicinal ingredients together, and then mixing the ingredients with a binding agent; and adhering the herbal medicine to a base sheet. The device for herbal medicine manufactured according to the method allows for persistent permeation of medical ingredients through mucous membrane with different release rate for each medicinal ingredient, and thus, the efficacy of the medicinal ingredient layer and the effect of treating disease can be maximized.

Method for extraction of Chinese herbal medicine using small molecule micro-shear technology
10953060 · 2021-03-23 ·

A method for extraction of Chinese herbal medicines using a small molecule micro-shear technology, including: pretreating, jet milling, grinding, pulverizing, cell-wall breaking, and extraction of Chinese herbal medicines, so that the raw material can be fully utilized. Herbs are cut into small molecule substances, which is easy to be absorbed by the means of a superfine grinding technology and a cell-wall breaking technology. By means of a supercritical carbon dioxide extraction technology, active ingredients in Chinese herbal medicines can be efficiently and singly extracted, and organic solvent residues in the raw herbs can be removed.

Method for extraction of Chinese herbal medicine using small molecule micro-shear technology
10953060 · 2021-03-23 ·

A method for extraction of Chinese herbal medicines using a small molecule micro-shear technology, including: pretreating, jet milling, grinding, pulverizing, cell-wall breaking, and extraction of Chinese herbal medicines, so that the raw material can be fully utilized. Herbs are cut into small molecule substances, which is easy to be absorbed by the means of a superfine grinding technology and a cell-wall breaking technology. By means of a supercritical carbon dioxide extraction technology, active ingredients in Chinese herbal medicines can be efficiently and singly extracted, and organic solvent residues in the raw herbs can be removed.

COMPOSITIONS AND METHODS FOR TREATING ECZEMA
20230414560 · 2023-12-28 ·

A pharmaceutical composition for the treatment of eczema is disclosed. Also disclosed are methods of treating eczema in a subject by administering a pharmaceutical composition.

COMPOSITIONS AND METHODS FOR TREATING ECZEMA
20230414560 · 2023-12-28 ·

A pharmaceutical composition for the treatment of eczema is disclosed. Also disclosed are methods of treating eczema in a subject by administering a pharmaceutical composition.