Disclosed are a traditional Chinese medicine composition and a traditional Chinese medicine extract composition for treating metabolic syndrome. The traditional Chinese medicine composition consists of the following raw materials in the following weight ratio: 5-80% of Coptidis Rhizoma, 5-70% of Aurantii Fructus Immaturus, 0-60% of Pinelliae Rhizoma, 0-40% of Trichosanthis Fructus, 0-12% of Cinnamomi Cortex, and 10-60% of red yeast rice. The traditional Chinese medicine extract composition consists of the following raw materials in the following weight ratio: 2-30% of Coptidis Rhizoma extract, and 70-98% of a mixed extract from five traditional Chinese medicines comprising Aurantii Fructus Immaturus, Pinelliae Rhizoma, red yeast rice, Trichosanthis Fructus, and Cinnamomi Cortex. The traditional Chinese medicine composition or the traditional Chinese medicine extract composition contains the following active ingredients (mg/g): 6-122 mg/g of total alkaloids, which comprises 4-89 mg/g of berberine, 30-315 mg/g of total flavonoids, which comprises 20-186 mg/g of neohesperidin: and 0.5-9 mg/g of lovastatin. Further provided are preparation methods and applications of the above compositions.

A pharmaceutical composition for treating oral ulcer, a preparation method and an application thereof are provided, which belong to the technical field of pharmaceutical compositions. The pharmaceutical composition includes the following raw materials: 20-50 parts of Sanhuang mixture, 15-20 parts of lotus root powder, 30-50 parts of Galla chinensis, 10-20 parts of Lonicera japonica Thunb., 10-20 parts of vanilla bean, 10-20 parts of propolis, 5-8 parts of oak bark, 5-10 parts of tea, 3-5 parts of Asarum, 1-2 parts of Atractylodes macrocephala and 5-30 parts of chlorhexidine acetate. The pharmaceutical composition for treating oral ulcer has the efficacies of clearing away heat, detoxifying removing blood stasis and reducing swelling, promoting granulation and relieving pain, inhibiting bacteria and killing bacteria, and has the advantages of quick response, easy finding of raw materials and low cost, and has a good therapeutic effect for treating oral ulcer clinically.

A pharmaceutical composition for treating oral ulcer, a preparation method and an application thereof are provided, which belong to the technical field of pharmaceutical compositions. The pharmaceutical composition includes the following raw materials: 20-50 parts of Sanhuang mixture, 15-20 parts of lotus root powder, 30-50 parts of Galla chinensis, 10-20 parts of Lonicera japonica Thunb., 10-20 parts of vanilla bean, 10-20 parts of propolis, 5-8 parts of oak bark, 5-10 parts of tea, 3-5 parts of Asarum, 1-2 parts of Atractylodes macrocephala and 5-30 parts of chlorhexidine acetate. The pharmaceutical composition for treating oral ulcer has the efficacies of clearing away heat, detoxifying removing blood stasis and reducing swelling, promoting granulation and relieving pain, inhibiting bacteria and killing bacteria, and has the advantages of quick response, easy finding of raw materials and low cost, and has a good therapeutic effect for treating oral ulcer clinically.

The present invention relates to compositions containing plant materials or extracts with inhibitory effect on a 5-HT.sub.3a and/or NK-1 receptor for preventing or treating idiopathic vomiting.

The present invention relates to compositions containing plant materials or extracts with inhibitory effect on a 5-HT.sub.3a and/or NK-1 receptor for preventing or treating idiopathic vomiting.

The present invention provides novel compositions for suppressing or improving hair loss, and compositions for suppressing or improving graying. More specifically, it provides agents that stabilize type XVII collagen expression, preferably agents that suppress the degradation of type XVII collagen by ELANE inhibitors and such, and compositions comprising a DNA repair-promoting agent or a DNA damage-suppressing agent as an active ingredient. Advantageous suppressive effects of hair loss and graying can be obtained when a composition comprising as an active ingredient a suppressive agent of type XVII collagen degradation such as an ELANE inhibitor is administered to a mammal. For the ELANE inhibitors, suppressive agents of type XVII collagen degradation and DNA repair-promoting agents, low-molecular compounds, polypeptides, proteins, antibodies, or nucleic acid medicine such as antisense oligos or siRNAs may be used. A method of screening for effective substances for suppression of hair loss and graying is also provided.

The present invention provides novel compositions for suppressing or improving hair loss, and compositions for suppressing or improving graying. More specifically, it provides agents that stabilize type XVII collagen expression, preferably agents that suppress the degradation of type XVII collagen by ELANE inhibitors and such, and compositions comprising a DNA repair-promoting agent or a DNA damage-suppressing agent as an active ingredient. Advantageous suppressive effects of hair loss and graying can be obtained when a composition comprising as an active ingredient a suppressive agent of type XVII collagen degradation such as an ELANE inhibitor is administered to a mammal. For the ELANE inhibitors, suppressive agents of type XVII collagen degradation and DNA repair-promoting agents, low-molecular compounds, polypeptides, proteins, antibodies, or nucleic acid medicine such as antisense oligos or siRNAs may be used. A method of screening for effective substances for suppression of hair loss and graying is also provided.

The present invention relates to a method for treating glioblastoma multiforme including administering a Chinese medicine composition to a subject in need thereof; wherein the Chinese medicine composition is an extract of a first mixture including Boswellia sacra, Commiphora molmol, Angelica sinensis, Ligusticum striatum, Rehmannia glutinosa, Paeonia veitchii, Prunus persica, and Carthamus tinctorius.

The present invention relates to a method for treating glioblastoma multiforme including administering a Chinese medicine composition to a subject in need thereof; wherein the Chinese medicine composition is an extract of a first mixture including Boswellia sacra, Commiphora molmol, Angelica sinensis, Ligusticum striatum, Rehmannia glutinosa, Paeonia veitchii, Prunus persica, and Carthamus tinctorius.

The present invention relates to a pharmaceutical carrier for active substances characterized in that it contains a strongly solvating aprotic solvent from the group of sulfoxides, a carbonic acid amide, and a vegetable oil with a high content of unsaturated fatty acids, and a pharmaceutical composition containing the carrier.