A system, method, and computer readable medium are provided that monitors at least one of an input and output stream for at least one of a presence of a material of interest and a concentration of the material of interest; when the material of interest is present and/or has at least a threshold concentration, directs the at least one of an input and output stream to a waste location or path to discard the material of interest; and when the material of interest is either not present or does not have at least a threshold concentration, directs the at least one of an input and output stream to a byproduct location or path to recover the material of interest.

A method of controlling actuation of a flush apparatus includes the steps of configuring a control module to actuate the flush apparatus for completing a flushing cycle periodically; and after a given unused time period of the flush apparatus, enabling the control module to enter into a sleep mode to stop an actuation of the flush apparatus. Therefore, during the rush hours, the control module is configured to actuate the flush apparatus frequently and during the off rush hours, the control module is configured to actuate the flush apparatus seldom.

A system, method, and computer readable medium are provided that monitors at least one of an input and output stream for at least one of a presence of a material of interest and a concentration of the material of interest; when the material of interest is present and/or has at least a threshold concentration, directs the at least one of an input and output stream to a waste location or path to discard the material of interest; and when the material of interest is either not present or does not have at least a threshold concentration, directs the at least one of an input and output stream to a byproduct location or path to recover the material of interest.

Disclosed is a sheath delivery system that uses a continuous flow of sheath fluid into a pressurized internal reservoir that substantially matches the outflow of sheath fluid through the nozzle of a flow cytometer. A substantially constant level of the sheath fluid is maintained. If the sheath fluid level falls below a desired level, or goes above a desired level, a dampened control system is used to reach the desired level. In addition, air pressure in the pressurized internal container is controlled so that an external sheath container can be removed and refilled with additional sheath fluid without stopping the sheath delivery system 100. Differences in pressure are detected by a droplet camera, which measures the droplet breakoff point to determine the pressure of the sheath fluid in the nozzle.

Apparatuses, systems, and methods are disclosed for fluid flow control. A container is shaped to receive a liquid, and includes an outlet configured to allow the liquid to exit the container. A valve is configured to control a fluid flow based on a liquid level in the container. An output line coupled to the valve is configured to convey the fluid flow from the valve to a location outside the container. The location outside the container does not receive the liquid directly from the outlet.

A pump cassette is disclosed. The pump cassette includes a housing having at least one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump. The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.

Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply.

Methods for managing a hazardous fluid within a pipeline and within a storage facility, and in particular for managing a potential or actual leak of the hazardous fluid. Such methods include the detection of such an event by one or more sensors, and the containment and the mitigation of the event.

Automated control mechanisms and methods for controlling fluid flow in a hemodialysis apparatus are described. The methods can involve a controller receiving information from a pressure sensor in a control chamber of a reciprocating diaphragm-based blood pump and causing the application of a time-varying pressure waveform on a diaphragm of the blood pump during a fill-stroke of the blood pump. The controller can be configured and programmed to monitor a pressure variation in the control chamber measured by the pressure sensor and to compare the measured pressure variation to a pre-determined value. Based on such comparison, the controller can initiate a procedure to pause or stop a dialysate pump of the hemodialysis apparatus if the magnitude of the measured pressure variation deviates from the pre-determined value.

A liquid storage tank has a breathing valve that vents the tank's headspace at a high-pressure value and admits an ambient gas at a low-pressure value. A controller generates a first control signal when the percentage of the catalyst gas is less than a catalyst threshold, a second control signal when the percentage of the catalyst gas exceeds the catalyst threshold, and a third control signal when the pressure in the headspace is equal to a low-pressure threshold between the breathing valve's low-pressure value and high-pressure value. The first valve is only opened to output inert gas at a discharge pressure greater than the breathing valve's high-pressure value in response to the second control signal. The second valve is only opened to output inert gas at a discharge pressure that is between the breathing valve's low-pressure value and high-pressure value in response to the third control signal.