A method is described for opening a heat bonded sterile connection that includes a skin of material blocking flow between the connection site. The method includes applying external pressure to the connection site.

A method is described for opening a heat bonded sterile connection that includes a skin of material blocking flow between the connection site. The method includes applying external pressure to the connection site.

A buckling pin valve and associated methods are disclosed. More specifically, a buckling pin valve is disclosed with a valve body having an inlet and an outlet, a valve seat at the valve body inlet, a valve plug configured to sealingly engage with the valve seat, a pin cage attached to the valve body and configured to mount a buckling pin, and a shaft configured to transfer forces from the valve plug to the buckling pin. A buckling pin valve also is disclosed with a pin cage being made of a rigid all-in-one construction. A method of manufacturing a pin cage for a buckling pin actuated valve is disclosed, wherein the method comprises fabricating a pin cage from a single piece of metal. A method of manufacturing a buckling pin actuated valve also is disclosed.

A fluid directing flow manifold for directing reactive fluids, independent of one another, from a dispensing manifold to a dispensing tip of a fluid dispensing apparatus provides a disposable and low cost fluid passageway between the dispensing manifold and dispensing tip while reducing or eliminating the possibility that reactive fluids will react and clog or block the dispensing manifold. The flow manifold provides independent fluid passageways between valves of a dispensing manifold and a mixing chamber of a dispensing tip of the dispensing apparatus. The flow manifold may be adapted for use with various types of fluid dispensing systems. The flow manifold may include multiple fluid guide bodies that may each be removed from the flow manifold to be cleaned or disposed of, and then replaced. Quick release mechanical fasteners are included for quick attachment of the manifold to a dispensing manifold valve and to the dispensing tip.

A drip chamber for an infusion tube that includes a first end arranged to receive a drip tube, a second end including an exit port, at least one wall connecting the first and second ends, a space enclosed by the first and second ends and the at least one wall, and first and second lenses each directly fixed to said at least one wall.

In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

In one aspect, a method provides a reciprocating bolt by a bolt assembly having a bolt assembly body, a cap affixed to the bolt assembly body, and a base affixed to the bolt assembly body opposite the cap. The method includes biasing a bolt carrier in the bolt assembly body in a retracted position relative to the bolt assembly, resulting in a center portion of a diaphragm disposed between the cap and the bolt assembly body being deflected toward the cap. The method also includes applying an actuation force to the bolt carrier so as to move the bolt carrier from the retracted position to an extended position relative to the bolt assembly by oppositely deflecting the center portion of the diaphragm toward the base, and discontinuing the applying of the actuation force while the bolt carrier is in the extended position.

A method for replacing a volume of coolant fluid in a circulating system in diesel engine system that includes the steps of establishing pneumatic connection with at least one location in the diesel engine coolant fluid circulating system; establishing fluid connection with at least one point in the diesel engine coolant fluid circulating system, the fluid connection location being different from the pneumatic connection; and after pneumatic and fluid connection is established, drawing a vacuum pressure through said pneumatic connection and introducing the volume of coolant fluid into the through said fluid connection as well as a device for accomplishing the same.

Pliable-wall air ducts with internal expanding structures are disclosed. An example air duct system includes an air duct including a pliable sidewall. The example air duct system further includes a shaft including a first end and a second end. The shaft extends in a longitudinal direction along a length of the air duct with the first end coupled to a first point of the air duct and the second end coupled to a second point of the air duct. The first point is downstream of the second point. The pliable sidewall is to be held in tension in the longitudinal direction between the first and second points in response to compression in the shaft between the first and second ends.

Apparatuses for preparing a sample are disclosed herein. The apparatuses include a chamber, a first valve at least partially disposed in the first chamber, a second valve at least partially disposed in the first chamber, and a pump comprising an actuator and nozzle.