The present invention relates to compositions containing, as their only active ingredients, an extract of Curcuma spp, optionally as curcumin in the form of a complex with phospholipids, and an extract selected from Echinacea spp extract or lipophilic extract of Zanthoxylum spp, which are useful in the topical and systemic treatment of peripheral pain and of superficial and deep inflammatory and painful conditions. The compositions according to the invention are particularly effective in the treatment of osteoarthritis and rheumatoid arthritis in patients unable to tolerate long-term treatment with NSAIDs or steroids.

The present invention relates to compositions containing, as their only active ingredients, an extract of Curcuma spp, optionally as curcumin in the form of a complex with phospholipids, and an extract selected from Echinacea spp extract or lipophilic extract of Zanthoxylum spp, which are useful in the topical and systemic treatment of peripheral pain and of superficial and deep inflammatory and painful conditions. The compositions according to the invention are particularly effective in the treatment of osteoarthritis and rheumatoid arthritis in patients unable to tolerate long-term treatment with NSAIDs or steroids.

The present invention relates to the use as an antimicrobial of tamarind seed polysaccharide (TSP) and to antimicrobial compositions which contain it as active ingredient. Antimicrobial compositions containing TSP are particularly useful for topical administration in the treatment and/or prevention of microbial infections of the skin and mucosa.

The present invention relates to the use as an antimicrobial of tamarind seed polysaccharide (TSP) and to antimicrobial compositions which contain it as active ingredient. Antimicrobial compositions containing TSP are particularly useful for topical administration in the treatment and/or prevention of microbial infections of the skin and mucosa.

The present invention relates to a topical synergistic anti-inflammatory formulation comprising a blend 1 to 6% by weight of Cymbopogon citratus oil (CC oil); 0.5 to 6% by weight of Zanthoxylum armatum oil (ZA oil); 0.5 to 6% in weight by Hedychium spicatum oil (HS oil). The invention also provides a method of management of the pain and/or inflammation by the formulations of the invention.

The present invention relates to a topical synergistic anti-inflammatory formulation comprising a blend 1 to 6% by weight of Cymbopogon citratus oil (CC oil); 0.5 to 6% by weight of Zanthoxylum armatum oil (ZA oil); 0.5 to 6% in weight by Hedychium spicatum oil (HS oil). The invention also provides a method of management of the pain and/or inflammation by the formulations of the invention.

The present invention relates to a topical synergistic anti-inflammatory formulation comprising a blend 1 to 6% by weight of Cymbopogon citratus oil (CC oil); 0.5 to 6% by weight of Zanthoxylum armatum oil (ZA oil); 0.5 to 6% in weight by Hedychium spicatum oil (HS oil). The invention also provides a method of management of the pain and/or inflammation by the formulations of the invention.

The present invention provides a phenylpropanoid compound and a preparation method and use thereof. The phenylpropanoid compound has a structural formula shown as formula (I), and the pharmaceutically acceptable salt has a structural formula shown as formula (II), formula (III), formula (IV), or formula (V). The phenylpropanoid compound and the pharmaceutically acceptable salt thereof have an effect on inhibiting a content of an inflammatory cytokine NO and an expression of an inflammatory cytokine TNF-, have an effect on inhibiting a hydroxyl radical (OH), thereby have anti-inflammatory and antioxidant activities, and has a good application prospect in preparing of a medicine for treating an inflammatory disease related to the above factors, such as cervicitis, endometritis, pelvic inflammatory disease, mastitis, sphagitis and/or arthritis.

##STR00001##

The present invention provides a phenylpropanoid compound and a preparation method and use thereof. The phenylpropanoid compound has a structural formula shown as formula (I), and the pharmaceutically acceptable salt has a structural formula shown as formula (II), formula (III), formula (IV), or formula (V). The phenylpropanoid compound and the pharmaceutically acceptable salt thereof have an effect on inhibiting a content of an inflammatory cytokine NO and an expression of an inflammatory cytokine TNF-, have an effect on inhibiting a hydroxyl radical (OH), thereby have anti-inflammatory and antioxidant activities, and has a good application prospect in preparing of a medicine for treating an inflammatory disease related to the above factors, such as cervicitis, endometritis, pelvic inflammatory disease, mastitis, sphagitis and/or arthritis.

##STR00001##

The present invention relates to the use as an anti-inflammatory of tamarind seed polysaccharide (TSP) and to anti-inflammatory compositions which contain it as active ingredient. Anti-inflammatory compositions containing TSP are particularly useful for topical administration in the treatment of inflammatory diseases of the skin and mucosa.