In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure.

In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure.

A vehicle fluid line for transporting high and low pressure fluids of an engine includes a rigid pipe having opposing ends configured to fixedly couple with the engine. An adjustable joint divides a length of the rigid tube into first and second segments. The adjustable joint has a cylindrical housing coupled with the first segment and having an inner diameter. A stop feature protrudes from an outer diameter of the second segment and interfaces with the cylindrical housing to prevent disengagement of the second segment from the housing. An elastomeric grommet is seated between the inner and outer diameters and is configured to maintain a fluid seal that allows the second segment to rotate axially, pivot radially, and slide longitudinally within the cylindrical housing.