Medicinal plant extracts and their bioactives from Alpinia, Magnolia, Kochia and Piper/Pepper are disclosed herein in combination or alone in regulating homeostasis of chondrocytes, extracellular matrix, articular cartilage, and phenotype of arthritis that lead to enhanced anabolic functions of chondrocytes, increased renewal/rebuilding/regeneration of extracellular matrix and articular cartilage, and improved phenotype of osteoarthritis and rheumatoid arthritis.

Medicinal plant extracts and their bioactives from Alpinia, Magnolia, Kochia and Piper/Pepper are disclosed herein in combination or alone in regulating homeostasis of chondrocytes, extracellular matrix, articular cartilage, and phenotype of arthritis that lead to enhanced anabolic functions of chondrocytes, increased renewal/rebuilding/regeneration of extracellular matrix and articular cartilage, and improved phenotype of osteoarthritis and rheumatoid arthritis.

Medicinal plant extracts and their bioactives from Alpinia, Magnolia, Kochia and Piper/Pepper are disclosed herein in combination or alone in regulating homeostasis of chondrocytes, extracellular matrix, articular cartilage, and phenotype of arthritis that lead to enhanced anabolic functions of chondrocytes, increased renewal/rebuilding/regeneration of extracellular matrix and articular cartilage, and improved phenotype of osteoarthritis and rheumatoid arthritis.

A method of treating vaginal atrophy is provided. The method comprises administering a vaginal care composition to vaginal tissue of a user experiencing a symptom of vaginal atrophy. The vaginal care composition may include an effective amount of a vaginal care agent selected to specifically treat symptoms of vaginal atrophy exhibited by the introitus and/or labia, based on the transcriptomic data of skin cells obtained therefrom. In some instances, the vaginal care composition may be applied to introitus and/or labia with a suitable implement configured for such use.

Various embodiments relate to formulations containing an extract of Alpinia galanga; a method of improving cognitive performance by administering an extract of Alpinia galanga; and a process for preparing an extract of Alpinia galanga.

Various embodiments relate to formulations containing an extract of Alpinia galanga; a method of improving cognitive performance by administering an extract of Alpinia galanga; and a process for preparing an extract of Alpinia galanga.

Various embodiments relate to formulations containing an extract of Alpinia galanga; a method of improving cognitive performance by administering an extract of Alpinia galanga; and a process for preparing an extract of Alpinia galanga.

The disclosure provides compositions comprising cannabinoids and active ingredients and/or excipients and methods of producing the compositions.

The disclosure provides compositions comprising cannabinoids and active ingredients and/or excipients and methods of producing the compositions.

Compositions and methods for increasing stress response and improving health and slowing the aging process in a user. A composition includes one or more of a first group consisting of milk thistle, ashwagandha, green tea, bacopa monnieri, and turmeric. The composition includes one or more of a second group consisting of acetyl-L-carnitine, quercetin, lipoic acid, coenzyme Q10, cysteine, and grape. The composition includes one or more of a third group consisting of mango leaf extract, wasabi, olive leaf extract, nicotinic acid, and copper gluconate.