A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.

Devices, systems, or methods are disclosed herein for treatment of disease in a vertebrate subject. The device can include a quasi-planar substrate; and one or more laterally-mobile effector molecule types at least partially embedded within the quasi-planar substrate, wherein the one or more laterally-mobile effector molecule types is configured to interact with one or more cell types. The device can further include one or more sensors configured to detect at least one aspect of an interaction between the at least one of the one or more laterally-mobile effector molecule types and the one or more cell types; and a controller in communication with the one or more sensors, wherein the controller is configured to responsively initiate modification of at least one of the one or more laterally-mobile effector molecule types, the quasi-planar substrate, and the one or more cell types.

An ion mobility spectrometer analytical instrument, including an ion mobility spectrometer, a swab interface, and a desorber assembly. The desorber assembly includes a heat transfer device configured to heat a desorber, as well as a supply configured to direct gas through the desorber. The instrument further includes a drift tube, high voltage device arrayed, at least in part, proximate to the drift tube, wherein the high voltage device is configured to change a polarity of a voltage applied to the drift tube and have an absolute voltage of about 500 to 1500 volts. The instrument further includes a reactant supply unit adapted to supply reactant during a sample substance analysis, and a control unit.

A method and system for automatic in-vitro diagnostic analysis are described. The method includes adding a first reagent type and a second reagent type to a first test liquid during a first and second cycle times respectively. The addition of the first reagent type to the first test liquid includes parallel addition of a second reagent type to a second test liquid during the first cycle time. The addition of the second reagent type to the first test liquid includes parallel addition of a first reagent type to a third test liquid during the second cycle time, respectively.

A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.

An automated analyzer includes two or more types of photometers to obtain suitable output of the measurement results of the plurality of photometers and suitable data alarm output even if there is an abnormality, or the like, at the time of measurement. The automated analyzer includes, for example, two types of photometers having different quantitative ranges and an analysis control unit for controlling analysis that includes measurement of a given sample using the two types of photometers. If two types of data alarms corresponding to abnormalities, or the like, during measurement have been added to the two types of measurement results from the two types of photometers, the analysis control unit selects measurement result and data alarm output corresponding to the combination of the two types of data alarms and outputs the same to a user as analysis results.

Oxidation/reduction measurement is described. An aspect provides an oxidation/reduction quantification method, including: receiving intermittent oxidizer/reducer reference measurements from one or more reference sensors; receiving one or more substantially continuous oxidizer/reducer-related measurements from one or more corroboration sensors; and processing the one or more substantially continuous oxidizer/reducer-related measurements with the intermittent oxidizer/reducer reference measurements to generate substantially continuous representative oxidizer/reducer measurements. Other aspects are described.

A temperature control device and method are provided for an analytical system for performing laboratory protocols. The device includes a well within a housing configured to receive a biological specimen according to a predetermined sample process. The specimen is suspended by a holding device in the well. A thermal element is provided in heat exchange communication with fluid in the well. A temperature sensor is located in the well at a location to be covered and uncovered by rocking motion of fluid in the well. A controller, in communication with the thermal element, the temperature sensor, and an agitation system, is operative to control the thermal element in correlation with temperature data, for example, peak temperature data, from the temperature sensor.

This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems.

Apparatuses for preparing a sample are disclosed herein. The apparatuses include a chamber, a first valve at least partially disposed in the first chamber, a second valve at least partially disposed in the first chamber, and a pump comprising an actuator and nozzle.