Patent classifications
A61K49/0419
MRI and CT contrast-enabled composite implants for image-guided tissue regeneration and therapy
A composite implant for providing simultaneous magnetic resonance imaging (MRI) and computed tomographic (CT) imaging contrast is disclosed. The composite implant is formed of a calcium compound in the form of nano or microparticles doped with a first dopant configured to provide MRI contrast and a second dopant configured to provide CT contrast. The calcium compound is loaded onto a polymer gel matrix and lyophilized to form a mass with 3-dimensionally interconnected porosity, configured to provide tissue integration and proliferation sites. Methods of forming the composite implant are also disclosed. The implant could be a scaffold or bead structured to enable treatment of human or animal patient for bone/cartilage injury or defect by implantation, with MRI and CT monitoring.
ECHOLUCENT IMPLANTS
Echolucent implantable materials may delivered to a selected placement site and biodegrade after a certain period of time. Applications include delivery of therapeutic agents to the placement site.
ECHOLUCENT IMPLANTS
Echolucent implantable compositions are described. Applications include materials for delivering of therapeutic agents to a tissue at a placement site.
ECHOLUCENT IMPLANTS
Echolucent implantable compositions are described. Applications include materials for delivering of therapeutic agents to a tissue at a placement site.
Imageable Polymers, Methods of Making and Methods of Use Thereof
Described herein are X-ray imageable polymers such as polymeric particles comprising bismuth as a radiopacifying agent, methods of making the polymers, and methods of using the polymers. The imageable particles may comprise a covalently bound compound which chelates the bismuth, for example, through a combination of nitrogen and oxygen atoms.
Medical device for detecting fluid parameters using fluorescent probes
An example device includes an elongated body defining a lumen, the elongated body comprising a proximal portion and a distal portion; and one or more sensors configured to: stimulate a fluorescence response from one or more fluorescent probes released into a fluid and flowing with the fluid through the lumen; and detect the fluorescence response, wherein the fluorescence response is indicative of a composition of the fluid.
INTELLIGENT ORGANIZATION OF MEDICAL STUDY TIMELINE BY ORDER CODES
A radiology viewer includes an electronic processor (10, 22), a display (12), input device(s) (14, 16), and a non-transitory storage medium storing executable instructions. Retrieval instructions (42) are executable to retrieve an index of prior radiology examinations (24, 26) from an electronic patient chart (20) in which the prior radiology examinations are indexed by at least date, imaging modality, and anatomical region and to retrieve billable order codes for the prior radiology examinations from an order management system (30). Organizing instructions (44) are executable to organize the prior radiology examinations into groups using features of the prior radiology examinations including features comprising or generated from the billable order codes for the prior radiology examinations. Viewer instructions (50) are executable to display an organized index of the prior radiology examinations on the at least one display in which the prior radiology examinations are organized into the groups.
Radiographic imaging apparatus
A radiographic imaging apparatus includes an imaging apparatus and a hardware processor. The imaging apparatus obtains moire fringe images for generating a reconstruction image of a subject by using a Talbot-Lau interferometer comprising a radiation source, a multiple slit, a first grating, a second grating and a radiation detector. The hardware processor performs a control to satisfy relations (i) (1/2)(R.sub.S/R.sub.1)d.sub.1>0.7, (ii) 110 (m), and (iii) 0.5(R.sub.s/R.sub.1)1. is a particle size of a microbubble contrast agent to be used in imaging. d.sub.1 is a slit period of the first grating. R.sub.1 is a distance between the multiple slit and the first grating. R.sub.s is a distance between the multiple slit and the subject.
BIODEGRADABLE RADIOPAQUE MICROSPHERE
A microsphere includes a radiopaque material, and a biodegradable material such that the microsphere can be detected using medical imaging and biodegrade after being administered to a patient.
Developable Hyaluronic Acid Microspherical Embolic Agent, Preparation Method and Use Thereof
A developable hyaluronic acid microspherical embolic agent includes a hyaluronic acid and an X-ray opaque contrast material; wherein the hyaluronic acid is a modified hyaluronic acid, wherein a modifying method for preparing the modified hyaluronic acid is cross-linking, grafting, esterification, or recombination, and is preferably cross-linking.