An antimicrobial light dressing device, system and method for a percutaneous treatment that bathes a treatment region around the percutaneous insertion with an antibacterial illumination source for preventing pathogens around the insertion from entering via the dermal puncture created by the insertion. The antimicrobial light dressing device combines a circumferential body centered around the insertion, and an arrangement of LEDs around the body that focus the light around the insertion and onto a therapeutic region of the insertion. An opening in the circumferential body has an articulated protrusion for offsetting a medicinal vessel such as an IV tube off the skin surface to avoid blocking light to an area under the vessel.

A method of disinfection of a surface of a subject of harmful microorganisms including pathogenic bacteria and viruses upon visible light irradiation using a genetically hybridized fluorescent silk is provided. The method includes placing a predetermined quantity of the genetically hybridized fluorescent silk i) directly on to a skin surface of a subject; or ii) on a medium and then placing the medium on the skin surface of the subject. The method further includes applying light in the visible spectrum for a predetermined amount of time to the placed quantity of genetically hybridized fluorescent silk.

A photoelectric device is disclosed. The photoelectric device includes a first electrode, a second electrode, and an electrolyte disposed between the first electrode and the second electrode. The second electrode includes a transparent layer for allowing light to penetrate into the second electrode, an electron transport layer coupled to the transparent layer, and a genetically hybridized fluorescent silk layer as a photo-sensitizer coupled to the electron transport layer.

A system for generating light radiation to neutralize microorganisms comprises a light source for emitting a light radiation, storage means with one or more unique identification codes, each of which is associated with a respective microorganism, and at least one respective wavelength range associated with said microorganism, and a logic control unit. The logic control unit is configured to select a wavelength range based on the microorganism to be neutralized, activate the light source in such a way that light radiation emitted by said light source has a wavelength within said selected wavelength range, so that, when the system is in use, the light radiation induces optical resonance in the microorganism, causing denaturation of genetic patrimony of the microorganism.

Control systems for disinfecting light systems and methods of regulating disinfecting energy generated by disinfecting systems are disclosed. The control system may include a first sensor and a second sensor positioned within a space illuminated by the disinfecting light system. The first sensor may measure an amount of disinfecting energy provided to the space by the disinfecting light system, and the second sensor may detect an environmental characteristic of the space. Additionally, the control system may include a controller operably coupled to the first and second sensor. The controller may regulate the disinfecting energy generated by the disinfecting light system by adjusting the amount of disinfecting energy provided to the space by the disinfecting light system in response to the amount of disinfecting energy provided to the space by the disinfecting light system measured by the first sensor, and/or the environmental characteristic detected by the second sensor.

Control systems for disinfecting light systems and methods of regulating operations of disinfecting light systems are disclosed. The control system may include a controller operably coupled to a disinfecting light fixture illuminating a space. The controller may regulate an operation of the disinfecting light fixture by adjusting an amount of disinfecting energy provided to the space by the disinfecting light fixture and/or adjusting an amount of illuminating light provided to the space by the disinfecting light fixture. The amount of disinfecting energy may be adjusted based on data relating to the space including disinfecting energy provided to the space, a bacterial load of the space, and/or environmental characteristic(s) of the space. Additionally, the amount of illuminating light may be adjusted based on data relating to the space including environmental characteristic(s) of the space, and/or a predetermined operational schedule for the space.

A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.

A lamp structure includes a casing, a circulation module, a power supply module, a light emitting module, an air vent, and a filter. A nano antiviral material composed of titanium dioxide and nanosilver is coated onto the filter installed at a lower end portion of the lamp structure, and the air circulation device is provided for obtaining fresh clean air after the air is filtered by the nano antiviral material and the filter, so as to achieve the effects of purifying air, deodorizing, resisting viruses and bacteria, and removing pollutants from the environment effectively for the area irradiated by the light of the lamp.

Disclosed are compounds of general formula (I): ##STR00001##
and pharmaceutically acceptable salts thereof, formulations, methods and uses in, for example, the treatment of disease.

Disclosed are compounds of general formula (I):

##STR00001##

and pharmaceutically acceptable salts thereof, formulations, methods and uses in, for example, the treatment of disease.