The present disclosure relates in general to nuclear medicine and generators for the production of radiopharmaceuticals for medical use. In particular, present disclosure relates to a generator column that resists high heat such as depyrogenation and sterilization. This allows some steps of the preparation of the column to be performed in a non-sterile environment. This also allows the generator column to be reusable. The present disclosure further describes methods for the preparation of a generator where a parent radioisotope is charged on the column matrix before or after the matrix is loaded in the column.

Single use medical devices that incorporate one or more destruct elements configured to deform during an autoclave cycle, rendering the device visually damaged or unusable. The use of such destruct elements prevents reuse (knowingly or unwittingly) of single use devices on patients after off-label autoclaving.

A removal device for removing at least one low-germ liquid from a conduit system is disclosed. The removal device comprises at least one removal connection piece. The removal device further comprises at least one coupling bend, which is detachably connected to the removal connection piece. At least one tube end of the removal connection piece protrudes into an interior of the coupling bend and is sterilizable with pure steam on its inner face, its outer face and its end face within the coupling bend.

A removal device for removing at least one low-germ liquid from a conduit system is disclosed. The removal device comprises at least one removal connection piece. The removal device further comprises at least one coupling bend, which is detachably connected to the removal connection piece. At least one tube end of the removal connection piece protrudes into an interior of the coupling bend and is sterilizable with pure steam on its inner face, its outer face and its end face within the coupling bend.

A container sanitizing system is provided. The system includes one or more containers, e.g., food containers, and a system to sanitize the containers. The container sanitizing system includes a sanitizing station adapted to receive the food containers and to irradiate the items with ultraviolet light at a sufficient intensity to sanitize and disinfect the items. The food containers are collapsible and may be folded into box-like food containers for the general storage of food, and subsequently, unfolded into a generally flat structure for sanitization within the sanitizing station. The system also includes a handheld sanitizing unit that is portable and/or mobile.

A fluid plug for use with sterile processes such as the manufacture or production of pharmaceuticals and biologics is disclosed. The fluid plug is made of a material or materials that will tolerate sterilizing processes such as gamma irradiation. The fluid plug is used to selectively plug the ends of flexible polymer conduits that may be connected to fluids, reagents, or products used or generated as part of the manufacturing process. Also disclosed is the use of the plugs in combination with a series of valves in a block-and-bleed arrangement to enable the sterile transfer and connection of fluids, reagents, or products within a process flow.

A fluid plug for use with sterile processes such as the manufacture or production of pharmaceuticals and biologics is disclosed. The fluid plug is made of a material or materials that will tolerate sterilizing processes such as gamma irradiation. The fluid plug is used to selectively plug the ends of flexible polymer conduits that may be connected to fluids, reagents, or products used or generated as part of the manufacturing process. Also disclosed is the use of the plugs in combination with a series of valves in a block-and-bleed arrangement to enable the sterile transfer and connection of fluids, reagents, or products within a process flow.

A high temperature food treatment method is disclosed wherein by alternatingly operating between a first final heater (13) and second final heater (23) arranged in parallel on a food processing line (30, 40, 50), it is possible to operate a continuous process, yet significantly reducing the overall downtime of the processing line (30, 40, 50), by performing a cleaning in place process on the final heater (13, 23), not currently being used in the high temperature food treatment process, thereby eliminating or significantly reducing the influence on the processing line (30, 40, 50) downtime by the process elements and/or processing equipment most easily contaminated.

A high temperature food treatment method is disclosed wherein by alternatingly operating between a first final heater (13) and second final heater (23) arranged in parallel on a food processing line (30, 40, 50), it is possible to operate a continuous process, yet significantly reducing the overall downtime of the processing line (30, 40, 50), by performing a cleaning in place process on the final heater (13, 23), not currently being used in the high temperature food treatment process, thereby eliminating or significantly reducing the influence on the processing line (30, 40, 50) downtime by the process elements and/or processing equipment most easily contaminated.

Systems are disclosed which include processor-executable program instructions for receiving data regarding characteristics of an area or a room and determining, based on the received data, operating parameter/s for one or more disinfection sources to disinfect the area/room. The data may include data regarding non-physical characteristics and/or physical characteristics of the area/room. In some embodiments, data regarding a quantity and/or type of at least a subset of the plurality of disinfection sources for disinfecting the room may also be considered for determining the operating parameter/s. In addition or alternatively, the data may be in relation to multiple disinfection sources in the area/room. In any case, a system is also disclosed which facilities power redirection among multiple disinfection sources upon detecting a given area has received a predetermined dose of ultraviolet light.