The present invention relates to devices, systems, and methods for controlling the concentration of potassium in dialysate in a closed loop potassium control system. The devices, systems, and methods can be compatible with any dialysis system including sorbent-based dialysis systems, single pass dialysis systems, or other multi-pass dialysis systems. The systems can use closed loop potassium control over potassium concentration in the dialysate to reduce the probability of patient arrhythmias. The potassium concentration can be controlled and personalized to a patient using certain predetermined patient parameters. Related systems, algorithms, and control systems are contemplated for optimizing the potassium concentration in the dialysate.

A method comprising: establishing a wireless connection between a first medical device and a second medical device, comprising: receiving, by the first medical device, via a short-range wireless technology protocol, connection information related to the second medical device; and establishing, by the first medical device, a wireless connection with the second medical device based on the connection information.

An example renal therapy system includes a blood pressure monitor configured to output blood pressure data concerning a patient and a renal therapy machine communicatively coupled to the blood pressure monitor. The renal therapy machine is configured to generate ultrafiltration (“UF”) removed data from a prescribed renal therapy treatment performed by the renal therapy machine on the patient, and transmit the UF removed data and the blood pressure data via a network. At least one of a UF trend or a blood pressure trend from the UF removed data or the blood pressure data is determined, enabling a further determination as to at least one of (a) whether a prescribed renal therapy treatment adjustment or a new prescribed renal therapy treatment needs to be made, (b) whether the patient is complying with the prescribed renal therapy treatment, or (c) whether a condition related to an alarm or an alert exists.

A control and/or regulation device, which is connected via signal link to a first input device, which in particular is operable by a doctor, and to a second input device, which in particular is operable by a patient, wherein the control or regulation device is programmed to control and/or regulate in signal link with a blood treatment

High-throughput microfluidic devices comprising one or more fluidic microchannels each with at least one flow-through 3D structure comprising a 3D electrode, or alternatively a 3D permselective structure, and optional secondary bead bed(s) are disclosed. Such devices can be used for counter-flow focusing of charged species via ion concentration polarization and in situ quantification of electrokinetically enriched charged species from an ionically conductive solution by both optical and electrical detection.

Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy.

An artificial heart and lung apparatus includes a roller pump; a blood removal line; a first blood transfer line; a blood removal rate sensor; a control unit that performs the linked control of the roller pump in correspondence with a blood removal rate; and a blood transfer rate adjustment unit that instructs the roller pump to transfer a blood transfer rate. The blood transfer rate adjustment unit includes an operation amount input unit to which an operation amount from an arbitrary circumferential position can be input, and which outputs a pulse signal according to the input operation amount. A counter adds and subtracts pulse signals output from the operation amount input unit, and outputs a resultant as blood transfer rate adjustment data. The counter performs a counting operation with respect to the circumferential position of the operation amount input unit when blood transfer control transitions to the normal control.

A home therapy machine is configured to perform a home therapy on a patient at a home or dwelling of the patient. The home therapy machine includes at least one processor operating a connectivity agent having an activated mode and a deactivated mode. When the connectivity agent is in the activated mode, the at least one processor is able to send data to and receive data from a system hub. When the connectivity agent is in the deactivated mode, the at least one processor is not able to send data to or receive data from the system hub. The home therapy machine further includes a user interface configured to receive a patient selection of a device program received from the system hub and at least one pump under control of the at least one processor for performing the home therapy according to the selected device program.

Systems and methods of generating a customized dialysate solution are provided. The system and methods use stock concentrates, with the addition of spikes to generate a customized dialysate solution based on the needs of the patient.

A pressure sensing device includes a case provided on a liquid flow path through a liquid, a diaphragm that is provided so as to divide a space in the case into a first space with the liquid flowing therethrough and a second space filled with a gas, a pressure sensor to measure pressure of the gas, and a diaphragm initial position adjustment mechanism capable of adjusting an initial position of the diaphragm to a desired position. The diaphragm initial position adjustment mechanism includes a reciprocating pump that includes a cylinder in communication with the second space, a plunger provided so as to be able to advance and retract within the cylinder, and a plunger driving part to advance and retract the plunger, and adjusts a filling amount of the gas filling the second space by advancing and retreating the plunger in the cylinder by the plunger driving part.