The present invention relates to a dialysis machine having an extracorporeal blood system; a dialysis fluid system having a dialyzer; having a control unit, wherein the dialysis machine furthermore comprises a balancing chamber having two balancing chamber halves for a balanced infeed and draining of dialysis fluid to and from the dialyzer, wherein a line is provided through which the dialysis fluid is conducted to the balancing chamber, and wherein a mixing chamber is provided in which the fresh dialysis fluid or a component thereof is located and which is directly or indirectly connected to a de-airing line closable by a valve; wherein the dialysis machine has a control unit that is configured such that the control unit opens and closes the valve once, or a number of times, in the operating state of the special air separation of the dialysis machine when the balancing chamber half of the balancing chamber in fluid communication with the named line is in its high-pressure phase.

A device and method for extracorporeal blood treatment, in particular for hemodialysis, and a method for the balance control of a dialysis fluid in an extracorporeal blood treatment. Sodium balancing can be implemented with improved accuracy during the blood treatment, because distorting effects in the conductivity measurement of the used dialysis fluid can be corrected by taking into account the loading of the used dialysis fluid with urophanic substances, which loading is sensed by an additional measuring apparatus.

A hemodialysis system is disclosed. The hemodialysis system includes a dialyzer, a saline container including saline, and a disposable set comprising a blood pumping tube fluidly connected to a first end of the dialyzer, an arterial line fluidly connected to a first end of the blood pumping tube, a venous line fluidly connected to a second end of the dialyzer, a saline line fluidly connected to the blood pumping tube and the saline container, and a dialyzer line fluidly connected to a second end of the blood pumping tube and a second end of the dialyzer. The hemodialysis system also includes a dialysis instrument comprising an arterial line clamp, a venous line clamp, and a saline valve. The saline rinses blood out of the arterial line when the venous line clamp is closed, the arterial line clamp is opened, and the saline value is opened.

The present invention relates to a method for regulating supply of substituate in an extracorporeal blood treatment with an extracorporeal blood treatment apparatus comprising a dialyzer divided by a semipermeable membrane into a blood chamber and a dialyzing fluid chamber and a device for supplying substituate. Moreover, the present invention relates to an extracorporeal blood treatment apparatus having a device for regulating supply of substituate. Regulation of supply of substituate in the extracorporeal blood treatment takes place as a function of the rheological loading of the dialyzer. To regulate supply of substituate during extracorporeal blood treatment, rheological loading of the dialyzer is determined from transmembrane pressure on the dialyzer and flow resistance of the dialyzer and substituate rate is increased or reduced according to the loading. The selection of dialyzer parameters or blood parameters is therefore no longer necessary and the distinction between pre-dilution and post-dilution is also made obsolete.

This disclosure relates to a method for determining a fluid balance between a first volume flow in a first section of a fluid circuit and a second volume flow of a second section of the fluid circuit. The method may also include adjusting, assuming or detecting a first temperature in the first section of the fluid circuit and a second temperature in the second section of the fluid circuit, or detecting a temperature difference between the first and the second sections. The method may also include detecting a second volume flow in a second section of the fluid circuit and forming a balance from at least the first volume flow and a corrected value of the second volume flow. The corrected value is determined from the detected second volume flow and the second temperature and/or the temperature difference.

A hemodialysis system is disclosed. The hemodialysis system includes a disposable set including a blood pumping tube, a fresh dialysate pumping tube, and a spent dialysate pumping tube. The hemodialysis system also includes a dialysis instrument including a blood pump head, a fresh dialysate pump head, a spent dialysate pump head, a first motor positioned and arranged to operate the blood pump head, a second motor positioned and arranged to operate the fresh dialysate pump head, and a third motor positioned and arranged to operate the spent dialysate pump head. When the disposable set is loaded into the dialysis instrument, the blood pumping tube comes into registry with the blood pump head, the fresh dialysate pumping tube comes into registry with the fresh dialysate pump head, and spent dialysate pumping tube comes into registry with the spent dialysate pump head.

The present invention relates to a method for filling a membrane filter of a blood treatment system, the blood treatment system comprising at least one blood treatment machine, a membrane filter, in particular a hollow fiber membrane filter, having a first and a second chamber which are semi-permeably separated by a membrane, and at least one first partial circuit and at least one second partial circuit. The first chamber of the membrane filter is arranged in the first partial circuit and the second chamber of the membrane filter is arranged in the second partial circuit. The first chamber of the membrane filter is filled with liquid via the first partial circuit, whilst the second chamber is still filled with air, and a pump is arranged in the first partial circuit upstream of the membrane filter. According to the invention,

This dialysis device is configured so that residual liquid in a powder container 42 and a bypass path 51 can be drained. Accordingly, the dialysis device is provided with: a first liquid draining path 71 connecting a clean water supply path 31 to a stock solution supply path 44 on the upstream side of a liquid feed pump 33; a second liquid draining path 72 connecting the clean water supply path to a dialysate discharge path 32 on the downstream side of the liquid feed pump; and an opening path 77 allowing a branch path 43 to communicate with the outer space by opening an on-off valve 78. By opening the on-off valve of the opening path and actuating the liquid feed pump, a liquid in the powder container 42 and a liquid in the bypass path 51 can be discharged through the first liquid draining path and the second liquid draining path.

The present invention relates to an apparatus for preparing a dialysis solution, wherein the apparatus has a dialyzate line for conducting a dialysis solution and has means that are configured to discontinuously convey a dialysis solution in the dialyzate line, wherein the apparatus has a conductivity sensor that is arranged to measure the conductivity of the dialysis solution, and wherein the apparatus has a concentrate line opening into the dialyzate line upstream of the conductivity sensor at an addition point and having a concentrate pump and has a concentrate container from which the concentrate pump conveys concentrate into the concentrate line and from this into the dialyzate line, characterized in that the apparatus has a controller that is connected to the conductivity sensor and to the concentrate pump and that is configured to control the concentrate pump such that the conductivity fluctuations over time in the dialysis solution downstream of the addition point are reduced with respect to a continuous concentrate conveying.

A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.