The present disclosure relates to a water purification apparatus that comprises a reverse osmosis device, RO-device, producing a purified water flow and to a corresponding method. The proposed method comprises detecting at least one fluid property of purified water in the purified water path and regulating a flow rate of water in the recirculation path to fulfill one or more predetermined criteria of the purified water in the purified water path, based on the at least one detected fluid property. The present disclosure also relates to a computer program and a computer program product implementing the method.

A dialyzer includes a dialysis unit including a blood channel and a dialysate channel; a dialysate supply channel configured to supply a dialysate to the dialysate channel; a dialysate discharge channel configured to discharge the dialysate from the dialysate channel; a blood supply channel configured to supply blood to the blood channel, and a blood discharge channel configured to discharge the blood from the blood channel. The dialysate contains nitric oxide and/or nitrite ions, and the concentration of the nitric oxide is 0.5 to 10 μM or the concentration of the nitrite ions is 40 to 120 μM.

The invention relates to a connection element (1) for a blood treatment device, in particular for a dialysis machine. The connection element (1) has here an inlet line (2), for letting in a fluid into the connection element (1), an outlet line (3), for letting a fluid out of the connection element (1), at least a first discharge line (21), for discharging a fluid from the connection element (1), wherein the first discharge line (21) is formed in a subsection (22) around the inlet line (2), and wherein the inlet line (2) and the first discharge line (21) are open to a first end section (23) of the connection element (1), and the first end section (23) is fluidically connected with the subsection (22).

The present invention relates to a device and to a method for producing dialysate, wherein the device comprises a first part and a second part designed as a circuit, wherein the first part comprises a water connection or a water container and the primary side of a filter, wherein the filter is designed to produce purified water from the water by forward osmosis, and wherein the second part comprises the secondary side of the filter, a reservoir, a filtrate line which leads from the secondary side of the filter to the reservoir, and a return line leading from the reservoir to the secondary side of the filter, wherein an electrodialysis unit comprising a diluate chamber and a concentrate chamber is further provided, wherein the concentrate chamber is fluidically connected to the secondary side of the filter.

The invention relates to a communications device for non-electric communication between fluidically interconnected devices, the communications device being designed to be mounted in a position in a fluidic overall system formed by the fluidically interconnected devices and to receive and/or emit non-electric signals, in particular in the form of pressure or sound signals, the non-electric signals being transmitted via a line that fluidically interconnects the devices. The invention further relates to a method for non-electric communication between fluidically interconnected devices, the non-electric communication taking place preferably by means of pressure and/or sound signals via at least one line that fluidically interconnects the devices.

The present invention relates to an apparatus and a method for preparing dialyzate, wherein the apparatus has a first part and a second part that is configured as a circuit; wherein the first part comprises a water connection or a water container as well as the primary side of a filter; wherein the filter is configured to prepare purified water from the water through forward osmosis; and wherein the second part comprises the secondary side of the filter, a reservoir, a filtrate line that leads from the secondary side of the filter to the reservoir, and a line leading from the reservoir to the secondary side of the filter, with the reservoir being a container having means for connecting the container to a dialysis machine.

A reverse osmosis (RO) system is described that is connectable to a dialysis machine and is capable of using heated purified water to clean and disinfect an external connection section or portion disposed between the RO system and the dialysis unit (or any other external heat tolerant device) without forming a closed loop system between both systems before and during a heat forward process. This can be accomplished without the need for direct/indirect or wired/wireless communication with the dialysis unit or the need to introduce a chemical cleaner or process that would require further rinsing after chemical disinfection.

A method and a system (10a) comprising an integrated water purifying apparatus (110) with a pre-filter circuit (402) including a particle filter and an activated carbon filter arranged to produce pre-treated water; a fluid circuit (404) arranged to receive pre-treated water from the pre-filter circuit (402), the fluid circuit (404) includes an RO-pump (450) and a Reverse Osmosis, RO, device, (301) arranged to produce purified water; a heating device (302) arranged to heat purified water from the RO device (301) to a temperature above 65°; the water purifying apparatus (110) is further arranged to heat disinfect the fluid circuit (404) using the heated purified water. The system (1) further comprises a line set (40) connected to the purified water outlet connector (128) at a water line connector (68) of the line set (40), wherein the line set (40) includes at least one sterile sterilizing grade filter (70a, 70b) arranged to filter the purified water into sterile purified water.

A method of reducing leakage current from a patient to a ground potential through an applied part of a medical device includes defining a maximum permissible leakage current A.sub.max from the patient to the ground potential when the patient is energized to an electric potential V and supplying the medical device with water having a resistivity value ρ through a fluid line having a length L and an inner diameter ID. The value of L and ID is selected to cause the fluid conduit filled with water of resistivity ρ to have a resistance of R high enough to maintain the leakage current from the patient to the ground potential below A.sub.max.

A method includes receiving, by a processor of a dialysis machine, a dialysate flow rate, a bicarbonate setting value, a signal from a pressure sensor configured to measure a pressure within a container, and a signal indicating a state of a fill valve; determining, based on the signal received from the pressure sensor and the state of the fill valve, fill parameters; determining a volume of the container based on at least two of the fill parameters; determining a depletion time in which the concentrate will be depleted from the container based on the volume of the container, the dialysate flow rate, and the bicarbonate setting value; determining, based on the depletion time, an amount of time remaining before the concentrate will be depleted from the container; and causing the dialysis machine to indicate the amount of time remaining before the concentrate will be depleted from the container.