A peritoneal dialysis apparatus includes a filter and a dialysis fluid circuit in fluid communication with the filter. The peritoneal dialysis apparatus also includes a pump for pumping fresh dialysis fluid to a peritoneum of a patient via the dialysis fluid circuit and pumping used dialysis fluid from the peritoneum of the patient through the dialysis fluid circuit and the filter. The peritoneal dialysis apparatus further includes a selective air access in fluid communication with the dialysis fluid circuit and a control unit configured to control the pump during a peritoneal dialysis treatment and a filter cleaning sequence. The control unit forms a fluid mixture during a filter cleaning sequence by opening the selective air access to mix air with a physiologically safe fluid. The fluid mixture is transferred across insides and/or outsides of the filter at least one time.

The disclosure relates to preparing an extracorporeal blood treatment apparatus. In an example, a disposable arrangement for use in the extracorporeal blood treatment apparatus includes at least one fluid-conducting device that is configurable to define a flow circuit that extends through a blood chamber of a dialyzer. The at least one fluid-conducting device comprises connectors for connection to a vascular system of a subject during a blood treatment. The disposable arrangement also includes a sterilizing filter. The disposable arrangement is configurable to define the flow circuit to form a closed loop that includes the sterilizing filter for priming the at least one fluid-conducting device.

In an embodiment, a dialysis machine includes a dialyser, a fluid line in fluid communication with the dialyser, an inlet valve enabling fluid to flow into the fluid line towards the dialyser during a dialysis treatment, a disinfectant line connected to the fluid line via a disinfectant valve upstream of the dialyser, the disinfectant valve enabling a disinfectant fluid to be provided to at least part of the fluid line during a disinfection procedure, and a controller programmed to open the inlet valve, while the disinfectant line is connected to a source of disinfectant fluid, to create a positive pressure gradient across the disinfectant valve as fluid flows into the fluid line towards the dialyser, the positive pressure gradient ensuring that the disinfectant fluid from the source of disinfectant fluid does not leak into the fluid line during the dialysis treatment.

A hemodialysis system is disclosed. The hemodialysis system includes a dialyzer and an online dialysate generation system comprising a water inlet line and a drain line. The hemodialysis system also includes a disposable set comprising a supply tube fluidly connected to online dialysate generation system and a dialysate pumping tube fluidly connected to the dialyzer. The hemodialysis system further includes a dialysis instrument comprising a dialysate pump head and a motor positioned and arranged to operate the dialysate pump head. The dialysis instrument operates the dialysate pump head to move fresh dialysate from the online dialysate generation system through the dialysate pumping tube to the dialyzer.

A dialysis machine comprising a fluid circuit for providing a dialysis fluid to a dialyzer is disclosed. The fluid circuit comprises a tube with a first valve for providing a disinfectant fluid for disinfecting at least a part of the fluid circuit at disinfection of the dialysis machine. The tube with the first valve is arranged to provide the disinfectant fluid upstream the dialyzer and at a position in the fluid circuit where pressure is, during treatment, such that a pressure gradient between ports of the first valve is provided, the ports comprising at least a disinfectant fluid port and a fluid circuit port, such that the disinfectant fluid port of the first valve is enabled to be safely connected to a source of disinfectant also during treatment. A method of controlling such a dialysis machine and a computer program for controlling are also disclosed.

A renal therapy apparatus includes a blood filter, a blood pump, a treatment fluid pump, and a control unit configured to control at least one of the blood pump or the treatment fluid pump during a filter cleaning sequence. In a first phase of the filter cleaning sequence, a first fluid including a blood-compatible and physiologically safe fluid is transferred back and forth across the insides and/or outsides of the blood filter. After the first phase, a second fluid is formed by mixing the first fluid with air. In a second phase of the filter cleaning sequence, the second fluid is transferred across the insides and/or outsides of the blood filter at least one time.

To provide a blood purification apparatus in which the hot-water-disinfection time can be optimized with consideration for environmental conditions. A blood purification apparatus provided with a dialyzer for giving dialysis treatment to a patient, and with a tube for introducing dialysate into or discharging drain liquid from the dialyzer. The apparatus includes a thermistor that is capable of detecting an environmental condition at a time of a hot-water-disinfection process in which the tube is disinfected with hot water or a parameter regarding the environmental condition, and an estimating device that estimates a hot-water-disinfection time required for the hot-water disinfection of the tube in accordance with the environmental condition or the parameter regarding the environmental condition detected by thermistor.

A method for priming a renal therapy machine is disclosed. The method includes communicating a source of a physiologically compatible solution with a blood circuit and moving the physiologically compatible solution from the source to the blood circuit. The method also includes moving the physiologically compatible solution through the blood circuit to prime the blood circuit. The method further includes moving the physiologically compatible solution from the blood circuit though porous fibers of a blood filter, causing air to be purged from the blood circuit and into a dialysis fluid circuit portion of the blood filter.

A leak may be detected in a heat exchanger of a hemodialysis device. A drain valve is opened by the controller, and then closed by the controller after a pre-selected time period. An initial pressure is determined in the spent dialysate circuit and stored in the memory. A system pressure is determined at periodic time intervals and compared to a pre-determined maximum pressure. The controller then determines whether the heat exchanger has a leak, in that in response to the system pressure exceeding a predetermined maximum pressure, a command is generated to execute an event including suspending a disinfectant operation with a disinfecting agent, and in response to the initial pressure subtracted from the system pressure being greater than a predetermined minimum pressure differential, a command is generated to execute an event including suspending the cleanse operation with the disinfecting agent.

A hemodialysis system according to an embodiment of the present invention includes a hydrochamber, and a water circuit for water to flow from an external water source into the hydrochamber via a water inlet valve. The hemodialysis system further includes a spent dialysate circuit for a disinfecting agent to flow to the hydrochamber via a recirculation valve during a disinfectant operation, and a drain valve disposed in the spent dialysate circuit. During the disinfectant operation, the hemodialysis system is adapted to replace a volume of the disinfecting agent exiting the spent dialysate circuit via the drain valve with an equal volume of water via the water inlet valve. The recirculation valve is directly connected to the hydrochamber such that in response to a pressure drop at the external water source, the disinfecting agent is prevented from backflowing through the water inlet valve.