The invention relates to an arrangement having a blood pump and a gas exchanger for extracorporeal membrane oxygenation. According to the invention, the blood pump is designed as a pulsatile blood pump and is arranged with the gas exchanger in the same housing. The pulsatile blood pump and the gas exchanger are preferably connected to the same gas source so that the blood pump can be pneumatically driven. The novel ECMO system has a simple design, is flexible, and in particular can be used directly on the patient.

A wearable mobile continuous ambulatory peritoneal dialysis (mCAPD) system, includes an mCAPD module mounted on a front portion of a wearable belt, wherein the mCAPD module comprises a micro-peristaltic pump disposed in a corresponding front portion, and an electronic control board connected to the micro-peristaltic pump for controlling and managing the mCAPD process, a fluid bag containing a dialysate fluid, attached to the wearable belt and to the electronic control board, and a sterile connector having a tube portion fixed into a guide section of the micro-peristaltic pump, and a first connecting end for connecting to a first tube inserted into a peritoneum cavity of the human body, and a second connecting end for connecting to a second tube attached to the fluid bag. Upon rotation, the micro-peristaltic pump enables a flow of fluid between the peritoneum cavity and the fluid bag.

An extracorporeal system for lung assist includes a housing which includes a blood flow inlet in fluid connection with a pressurizing stator compartment, a fiber bundle compartment in fluid connection with the pressurizing stator compartment via a flow channel within the housing, and a blood flow outlet in fluid connection with the fiber bundle compartment. An impeller is rotatably positioned within the pressurizing compartment. The system further includes a fiber bundle within the fiber bundle compartment. A plurality of hollow gas permeable fibers of the fiber bundle extend generally perpendicular to the direction of bulk flow of blood through the fiber bundle compartment from the flow channel to the blood flow outlet.

The present invention relates to a sorbent manifold and related systems and methods having a plurality of passageways fluidly connectable to one or more valves and one or more sensors and components for use in a sorbent dialysis system. The sorbent manifold can control the one or more valves to direct fluid to either pass through a sorbent cartridge or bypass the sorbent cartridge based on measurements obtained from sensors.

To enhance diffusive mass transfer of small molecules and convective clearance of middle molecules, the present invention provides a cylindrical hemodialyzer which comprises a blood compartment having a packed bundle of hollow fibers in a doughnut configuration on a radial cross-section, and a motorized dialysate compartment comprising a dialysate inlet motor having an external stator and an internal rotor connected to an axial spiral flow converter slidably inserted in a center of the packed bundle of the hollow fibers. The cylindrical hemodialyzer is configured to recirculate dialysate across the packed bundle of the hollow fibers propelled by the dialysate inlet motor. A dialysate outlet motor of the motorized dialysate compartment having an external stator and an internal rotor is configured to drain the dialysate and to control ultrafiltration by said cylindrical hemodialyzer.

A dual lumen drainage cannula configured for use in a VA ECMO system includes a first drainage tube having a proximal end, a distal end, and at least one aperture in at least one wall of the first drainage tube proximate to the distal end of the first drainage tube, and a second drainage tube having a proximal end, a distal end, and at least one aperture in at least one wall of the second drainage tube proximate to the distal end of the second drainage tube. The first drainage tube passes through the second drainage tube. The dual lumen drainage cannula also includes a sleeve positioned adjacent to an interior wall of the second drainage tube. The sleeve is formed of a flexible material so as to be expandable and collapsible within the second drainage tube.

The invention pertains to a medical device: an ECMO (extracorporeal membrane oxygenation) catheter which can be used during right heart and lung failure. It pertains to a dual lumen catheter with a single port of entry which when in place bypasses the right heart and lungs while completing the veno-arterial circuit.

To enhance diffusive mass transfer of solutes, the present hemodialyzer in a cylindrical configuration for hemodialysis comprises a blood compartment having a packed bundle of hollow fibers in a reversibly distensible doughnut configuration on a radial cross-section, and a dialysate compartment having an axial spiral flow converter slidably inserted in a center of the packed bundle of the hollow fibers and an outer circumferential space encircling an outer circumferential layer of the packed bundle of the hollow fibers. The axial spiral flow converter is configured to convert an axial dialysate flow to a centrifugal dialysate flow radially spreading from the center of the packed bundle of the hollow fibers to the outer circumferential space of the hemodialyzer.

A dialysis machine has a blood circuit, a blood pump, a dialyzer, a venous pressure sensor, a substituate line, and a control unit. The control unit can operate the blood pump in a first operating mode and in a special operating mode, and start the special operating mode after a trigger event. In the special operating mode, a blood pump conveying rate is controlled via a default value or regulated to a desired value, with the default or desired value being derived from a value determined before the started special mode or corresponding to the value. The presence of an obstacle is polled before the special mode, and depending on the presence thereof, the start of the special mode is blocked or delayed and/or the selection of the default value or the desired value on the presence of the obstacle differs from the selection without the presence of the obstacle.