A blood purification apparatus configured such that the connection of a chamber member is prevented from being forgotten when blood purification treatment is performed after the switching to a single-needle state. A blood purification apparatus is arbitrarily switchable between a double-needle state and a single-needle state and includes a blood pump 4, a delivery-amount-detecting unit 11 configured to detect the amount of liquid delivery made with the operation of the blood pump 4, a pressure detector 6 configured to detect the pressure in a blood circuit, a chamber member 9 connected to an air-trap chamber 5 in the single-needle state and configured to receive and store the blood in the blood circuit in a blood-collection phase in which blood is collected from the patient and to discharge the stored blood into the blood circuit in a blood-return phase in which the blood is returned to the patient.

The present disclosure relates to a medical device, in particular a blood cassette, having a device body and having at least one fluid reception chamber for receiving at least one first medical fluid, in particular blood. The blood cassette can also have a hydrophobic filter device through which the fluid reception chamber is supplied with at least a second gaseous fluid, in particular air. The filter device comprises a filter membrane welded to the fluid reception chamber. The filter device also comprises a front support structure on or at front side, which is arranged for supporting the filter membrane.

Methods and systems for processing and conditioning red blood cells are disclosed. The methods and systems may be used to make a readily transfusible red blood cell product with reduced plasma. In general, the plasma content of the supernatant of the red blood cell product is no greater than about 15%. The red blood cell products are prepared using the disclosed methods and systems remain transfusible for up to 42 days.

A device and a method are provided for blood treatment in a single-needle operating mode. The blood treatment device has an extracorporeal blood circuit comprising a blood supply line leading to the inlet of a blood treatment unit and a blood return line leading away from the outlet of the blood treatment unit. A blood collecting container is provided in the blood return line, and is connected to an air reservoir by a flow line. The flow connection comprises two line branches, one branch being used to transfer gas from the air reservoir into the blood collecting container and the other branch being used to transfer gas from the blood collecting container into the air reservoir. The connection branch for transferring gas from the air store into the blood collecting container can contain a compressor.

An ambulatory ultrafiltration device includes a blood filter that has a blood side or fluid communication with the vascular system of the subject, an ultrafiltrate side, and a semipermeable membrane disposed between the blood side and the ultrafiltrate side. The ambulatory ultrafiltration also includes a buffer vessel in fluid communication with the blood side of the blood filter, and a blood pump. The blood pump is controlled to alternate between a withdrawal phase and a return phase. In the withdrawal phase, blood is withdrawn on a blood path from the subject via the blood filter to the buffer vessel. In the return phase, blood is returned from the buffer vessel to the subject on the blood path. The blood filter is arranged to remove ultrafiltrate from the blood during at least one of the withdrawal and return phases.

An apparatus is described for extracorporeal blood treatment comprising an extracorporeal circuit (2), a first pump (13) operating at the removal line (3) of the blood, a second pump (14) operating at the return line (7) of the blood to the patient, a first blood reservoir (21) operating on the blood return line (7) upstream of the second blood pump (14) and a sensor (22) predisposed to detect at least a parameter, for example the pressure in the first reservoir; a control unit (100) connected to the first pump (13), to the second pump (14) and to the sensor (22) is configured such as to control the first pump (13) to promote removal of the blood along the removal line and the movement of the second pump (14) to promote the return of the blood to the patient along the return line, the control of the second pump being carried out on the basis of the signal emitted by the sensor acting on the first reservoir.

A device and a method are provided for blood treatment in a single-needle operating mode. The blood treatment device has an extracorporeal blood circuit comprising a blood supply line leading to the inlet of a blood treatment unit and a blood return line leading away from the outlet of the blood treatment unit. A blood collecting container is provided in the blood return line, and is connected to an air reservoir by a flow line. The flow connection comprises two line branches, one branch being used to transfer gas from the air reservoir into the blood collecting container and the other branch being used to transfer gas from the blood collecting container into the air reservoir. The connection branch for transferring gas from the air store into the blood collecting container can contain a compressor.

A disposable for use in blood treatment including a blood treatment unit and two membrane pumps connected in parallel on one side of the blood treatment unit. The disposable is operable in a single-needle mode, in which the pumps generate a pulsatile flow of blood through the blood treatment unit, and in a double-needle mode, in which the pumps generate an essentially continuous flow of blood through the blood treatment unit. The pumps connect to a supply of treatment fluid such that alternating flows of treatment fluid causes the pumps to generate the desired flows of blood in the single-needle and double-needle modes. The treatment fluid may be used as motive fluid for displacing the blood in the membrane pumps and/or as control fluid for controlling opening and/or closing of upstream and downstream commutation valves in the membrane pumps.

The disclosure provides a manual blood or body fluid treatment system comprising first and second reservoirs for holding a batch of blood from a patient and a filter for performing an extracorporeal treatment on blood passing therethrough by removing waste molecules and/or fluid. The first reservoir is constructed to be displaced vertically relative to the second reservoir and vice versa, such that a height difference between the first and second reservoirs causes blood or body fluid to flow between the reservoirs due to gravity.