A fluid preparation system has a sealed sterilized fluid circuit with a sealed sterilized container with a conductivity sensor in communication with an interior of said container. Further, at least one sealed connector is adapted for adding fluid to said container, and at least one sealed connector is adapted for removing fluid from said container. The conductivity sensor is contained in a test line in communication with said interior and is adapted to be connected to a source of suction thereby to draw a sample of contents of said container. Furthermore, the test line may have a check valve to prevent ingress of contaminants into said container, and the sealed connector is adapted for adding fluid to said container and may have an inline sterile filter. Furthermore, the system may have a controller that controls pumping actuators.

An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.

A hemodialysis system is provided and includes a dialyzer, a dialysis fluid circuit in fluid communication with the dialyzer, a blood circuit, a blood detector and a blood rinseback scheme, wherein the blood rinseback scheme includes transferring blood to the patient using a physiologically acceptable fluid, wherein the physiologically acceptable fluid is introduced from its source into an arterial line between an arterial line patient end and a blood pump of the blood circuit, and flowed through the dialyzer, through a venous drip chamber and to the blood detector along a venous line of the blood circuit, where the physiologically acceptable fluid is sensed by the blood detector to indicate an end of the blood rinseback.

A hemodiafiltration (HDF) system is provided for performing HDF treatment. The HDF system includes a mixing system for mixing nitric oxide (NO) with other chemicals to produce a dialysis fluid. The HDF system further includes an extracorporeal blood circuit that includes a filter for separating the dialysis fluid into a dialysate and NO spiked substitution fluid. The extracorporeal blood circuit also includes a dialyzer that receives the dialysate and a blood line connected to the dialyzer. The blood line includes admission points connected to the filter. The admission points are used to administer the NO spiked substitution fluid to the patient during the HDF treatment.

The present disclosure relates to a filter module for a medical fluid delivery system capable of removing cytokine inducing substances (CIS) from a medical fluid.

A renal therapy blood cleansing system is provided. The renal therapy blood cleansing system includes a blood circuit including a blood filtering device, a therapy fluid circuit including a balance chamber configured to exchange like volumes of fresh and used therapy fluid, a first pump configured to pump fresh therapy fluid to the balance chamber, a second pump configured to pump used therapy fluid to the balance chamber, and at least one valve located downstream from the balance chamber, the at least one valve enabling fresh therapy fluid from the balance chamber to be directed selectively to (i) a flow path leading to an inlet of the blood filtering device, or (ii) a flow path leading to the blood circuit at a location upstream or downstream of the blood filtering device.

The present invention relates to a blood treatment apparatus: at least one first source for a saline solution, a fresh dialysate, or a substituate as a first fluid; at least one first conduit portion which connects to the first source; at least one second source of a second fluid in the form of a concentrate or a solution; at least one second conduit portion which connects to the second source; at least one third conduit portion, which is in fluid communication with a section of the extracorporeal blood circuit to which both the first conduit portion and the second conduit portion are fluidly connected such that both the first source and the second source are in fluid communication with the third conduit portion; a first fluid conveying device, arranged to convey a fluid present inside the third conduit portion. The invention further relates to a corresponding method.

This disclosure relates to detecting fluid in medical tubing. In certain aspects, a method is performed by a data processing apparatus. The method includes controlling repetitive activation of the ultrasonic transmitter. The method also includes receiving a signal from the ultrasonic receiver during an activation of the ultrasonic transmitter. The method also includes determining that fluid is absent or present in a portion of the medical fluid tube based on a comparison between the signal and a threshold value.

A blood purification apparatus capable of performing pre-substitution and post-substitution simultaneously is provided. A patient's blood flows through an arterial blood circuit and reaches a dialyzer. The blood purified by the dialyzer flows through a venous blood circuit and returns into the patient. A first substitution pump delivers substitution fluid through a substitution line to a branching point. A pre-substitution line connects the branching point and the arterial blood circuit to each other and is provided with a second substitution pump at a halfway position thereof. A post-substitution line connects the branching point and the venous blood circuit to each other and is provided with a check valve at a halfway position thereof. When the two pumps are activated simultaneously, the substitution fluid is supplied to the arterial blood circuit (pre-substitution). When only the first substitution pump is activated, the substitution fluid is supplied to the venous blood circuit (post-substitution). When the flow rate of the second substitution pump is set higher than the flow rate of the first substitution pump, pre-substitution and post-substitution are performed simultaneously.

The present invention relates to a blood treatment apparatus having an extracorporeal circuit, having a dialyzate circuit and having a dialyzer which has a blood-side chamber and a dialyzate-side chamber which is separated from the blood-side chamber by a membrane, characterized in that the blood-side chamber is in fluid communication with the extracorporeal circuit and the dialyzate-side chamber is in fluid communication with the dialyzate circuit, and having a preparation unit for the online preparation of a solution, characterized in that the blood treatment apparatus has first means for carrying out a priming mode and has second means for carrying out an initial treatment mode, wherein the first means are configured such that they control the preparation unit such that a flushing solution having a pH of 7.3, and preferably of 7.4, is prepared and such that the extracorporeal circuit is filled with this flushing solution, and the second means are configured such that they control the preparation unit such that dialyzate having a pH of 7.3, and preferably of 7.4, is prepared, and such that the dialyzate circuit is filled with this dialyzate, wherein the blood treatment apparatus has a control or regulation unit which operates the first means before the second means.