Systems, methods, and devices for preparation of purified water and medicaments for various uses including blood treatment are described. Methods, devices, and systems for creating multiple-treatment batches are described. For example, a medicament fluid circuit can include a container with an interior chamber. The container can have a fluid filling port and a fluid extraction port. Both ports can be connected to the interior chamber. The filling port can have two sterilizing filters, each of which has a membrane. The sterilizing filters can be connected in series the membranes are separated by a distance of at least 0.5 cm. A first of the sterilizing filters can have a sealed inlet. The fluid extraction port can be sealed.

Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands.

This disclosure relates to detecting fluid in medical tubing. In certain aspects, a method is performed by a data processing apparatus. The method includes controlling repetitive activation of the ultrasonic transmitter. The method also includes receiving a signal from the ultrasonic receiver during an activation of the ultrasonic transmitter. The method also includes determining that fluid is absent or present in a portion of the medical fluid tube based on a comparison between the signal and a threshold value.

A system for filling multiple sterile containers includes a filter with an inlet port and multiple outlet ports, the outlet ports being pre-attached to sterile containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines are connected to a respective container interior. The respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. A container that is connectable to an outlet port the system has a bladder, a first tube and a second tube connected to the bladder, and a sterilizing filter. The container, the first tube and the second tube, and the sterilizing filter are sterile before water is flowed through the sterilizing filter into the bladder.

A fluid treatment plant has a filter module including at least a first filter and a second filter connected in series and connectable to a supply of fluid. A pump is fluidly connected to the filter module and a controller with a fluid quality sensor is connected to detect a quality of the fluid between the first filter and the second filter. A filter module detector is connected to the controller configured to uniquely detect a filter module connected to the pump, and the controller is controls the pump responsively to a signal from the fluid quality sensor and the module detector. The controller is configured to continue pumping based on output of the quality sensor and/or based on output from the filter module detector.

A water supply system is operable to extract liquid water, EW, from waste fluid, WF, generated by a dialysis system and to provide the liquid water for use by the dialysis system. The water supply system comprises a dehumidifier sub-system and a humidifier sub-system. A gas stream is circulated between the sub-systems and is alternately humidified and dehumidified. The liquid water is extracted from the gas stream by the dehumidifier sub-system. The humidifier sub-system comprises a membrane distillation unit with a feed side and a draw side separated by a hydrophobic membrane. The waste fluid is supplied on the feed side and the gas stream is supplied on the draw side, and water vapor is transported from the waste fluid through the membrane via a difference in partial water vapor pressure between the feed and draw sides.

An apparatus for extracorporeal blood treatment comprising a filtration unit, a blood circuit comprising a blood withdrawal line and a blood return line, and a fluid circuit. The fluid circuit comprises at least one or more water inlet ducts for receiving water, a dialysis preparation assembly comprising one or more concentrated sources housing a respective concentrate solution and configured to prepare a mixed solution of a dialysis fluid, wherein the water inlet duct is configured to provide water to the dialysis preparation assembly for preparing said mixed solution of dialysis fluid. The fluid circuit further comprises an infusion preparation assembly comprising one or more concentrated sources housing a respective concentrate solution and configured to prepare a mixed solution of an infusion fluid, wherein the water inlet duct is configured to provide water to the infusion preparation assembly for preparing said mixed solution of infusion fluid.