Described are embodiments that include methods and devices for separating composite liquids into components. Embodiments involve the use of a flexible membrane for separating a composite liquid into components. The composite liquid may include, in embodiments, a cellular containing liquid, such as whole blood or components of whole blood. In one specific embodiment, the composite liquid is a buffy coat.

A photopheresis system (200) is disclosed, and that may be configured to execute one or more protocols. These protocols include: 1) protocols (400; 430; 460) for purging air out of a centrifuge bowl (210) used by the photopheresis system (200); 2) protocols (500; 510 550) for assessing the installation/operation of one or more pressure domes (330) used by the photopheresis system (200); and 3) protocols (580; 600; 660; 700; 740) for collecting buffy coat from blood processed by the photopheresis system (200).

A method for adjustment of a dialysate during dialysis for a patient is provided. A patient undergoing a dialysis treatment, e.g., a hemodialysis (HD) treatment, can experience multiple physiological changes during the treatment. These can include change in blood volume as well as change in concentration of blood electrolytes. Blood electrolytes when taken out of their desired ranges can result in one or more health risks. The disclosure provides a way of avoiding those health risks by adjusting composition of dialysate during dialysis treatment such that blood electrolytes are maintained within their desired ranges.

A washed platelet having a sufficiently low blood plasma content rate is more securely and efficiently obtained.

A tertiary separator (42) includes a main body (58) which has a third chamber (52) and is formed as an accommodating portion (54a) accommodating a centrifuged platelet (104), an inlet (77c) which allows a platelet containing component (100) and a platelet added solution (102) to flow in, and an outlet (78a) which allows blood plasma, the platelet added solution (102), and the platelet (104) to flow out. A bottom portion (first bottom portion (60)) of at least a portion forming the accommodating portion (54a) in a wall portion included in the main body (58) is formed of a soft material.

Described are embodiments that include methods and devices for separating composite liquids into components. Embodiments involve the use of a flexible membrane for separating a composite liquid into components. The composite liquid may include, in embodiments, a cellular containing liquid, such as whole blood or components of whole blood. In one specific embodiment, the composite liquid is a buffy coat.

The invention relates to an external function device which has at least one housing body having at least one chamber integrated into it for holding medical fluids and at least one locking device for releasably holding an accessory part.

Methods and systems for cryopreservation of platelets are disclosed. Platelets collected in a collection chamber of a plateletpheresis device may be combined with a cryopreservative solution directly in the collection chamber and joined with a kit including a storage unit for storage in a cryopreserved state and thawing.

Methods and systems for processing biological fluid are disclosed. The methods and systems allow for processing of biological fluid to continue in the event that certain non-operator-correctable hardware errors of a non-critical nature are detected during such processing.

The specification discloses a portable dialysis machine having a detachable controller unit and base unit with an improved reservoir heating system. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a reservoir with an internal pan and external pan, separated by a space that holds a heating element. The heating element is electrically coupled to electrical contacts attached to the external surface of the external pan.

A platelet collection method includes a step of accommodating whole blood in a first chamber (44) and performing centrifugal separation, a step of transferring a buffy coat resulting from the centrifugal separation to a second chamber (50), and a step of performing centrifugal separation on the buffy coat. Subsequently, a step of transferring a platelet-containing component resulting from the centrifugal separation to a third chamber (52) and a step of performing centrifugal separation on the platelet-containing component are executed. Also performed in the collection method are a step of introducing a platelet additive solution into the third chamber (52) and replacing plasma resulting from the centrifugal separation and a step of collecting platelets remaining in the third chamber (52) along with the platelet additive solution.