A thermal control system for controlling a temperature of a fluid delivered to a patient is provided. The system includes a thermal control unit having a fluid inlet and outlet, a circulation channel, a pump, a heat exchanger, a fluid temperature sensor and a controller that controls the heat exchanger in order to automatically bring a patients temperature to a target temperature. In some embodiments, the control unit includes a user interface adapted to receive a non-temperature patient parameter (e.g. BMI) that the controller uses, along with patient core temperature readings, to control the heat exchanger. The controller may also or alternatively control the heat exchanger based on both core and peripheral patient temperature readings. An auxiliary thermal therapy device for controlling a temperature of the patients blood, air breathed by the patient, and/or other fluid, may also be controlled by the thermal control unit.

A fluid separation device includes a centrifuge in which a fluid is separated into at least two components, with an interface therebetween. At least a portion of one of the separated fluid components is removed from the centrifuge and flows through a vessel. Light is reflected off of the separated fluid component in the vessel and received and analyzed to determine its main wavelength. If the main wavelength is higher than a maximum value, a target location of the interface is changed. If the main wavelength is less than the maximum value, then the location of the interface is compared to the target location. When the interface is sufficiently close to the target location, the optical density of the separated fluid component in the vessel is compared to a minimum value. If the optical density is less than the minimum value, the target location of the interface is changed.

The present disclosure relates to a blood hose set, or to an extracorporeal blood circuit, for a single-needle treatment. In some embodiments, the set includes: a patient hose line and a Y-shaped connector or three-way connecter, which is connected to the patient hose line.In some embodiments, the blood hose set does not include any single-needle chamber in a blood path or on a blood side, nor is it connected to any single-needle chamber provided in a blood path or on a blood side. The present disclosure further relates to a control device or closed-loop control device, a blood treatment apparatus, a method for the single-needle treatment, a digital storage medium, a computer program product and a computer program.

A medical apparatus, such as a dialysis machine (e.g. a hemodialysis machine or a peritoneal dialysis machine), includes a plurality of components, one or more sensors corresponding to the components and configured to detect signals, a display and a control unit. The control unit is configured to: receive signals from the one or more sensors, determine, from the signals, a status of the medical apparatus, and determine control commands for the display based on the determined status for status-dependent control of the display. The described apparatus improves the human-machine interface in terms of set-up time, operating time and freedom from errors. Depending upon the determined status, different status-specific menus may be illustrated on the display in order to assist the user when operating the apparatus or advise the user about any errors or subsequent steps.

A method is provided for removing red blood cells from a suspension comprising red blood cells, white blood cells, platelets and plasma using a spinning membrane separator. The method comprises: a) flowing whole blood into the gap of the spinning membrane separator; b) collecting red blood cells and white blood cells in the gap and passing plasma and platelets through the membrane; c) introducing a first quantity of lysing buffer into the gap; d) incubating the red blood cells, white blood cells and lysing buffer in the gap for a period of time to cause a lysis reaction with the red blood cells; e) introducing a second quantity of lysing buffer into the gap to displace the first quantity of lysing buffer and a first quantity of red blood cell debris out of the gap; f) introducing a first quantity of wash buffer into the gap to quench the lysis reaction and displace the second quantity of lysing buffer and a second quantity of red blood cell debris out of the gap; and g) introducing a second quantity of wash buffer into the gap to flow washed white blood cells out of the housing.

A colorimetric optical sensor device includes a broadband light source configured to emit a light that is exposed to a fluid in a vessel. At least a portion of the light is reflected off of the fluid and received by an optical spectrometer. The optical spectrometer analyzes at least a portion of the received light to determine a main wavelength of the light. A controller correlates the main wavelength to a corresponding hematocrit or free hemoglobin concentration and generates an output indicative of the hematocrit or the free hemoglobin concentration of the fluid. The hematocrit or free hemoglobin concentration information may be used by a separation assembly in which the colorimetric optical sensor device may be incorporated to modify a separation procedure in which the monitored fluid is to be separated or is a component or constituent of a previously separated biological fluid.

Graphical user interfaces for use with extracorporeal blood treatment systems may include one or more bar-type parameter adjustment elements. The bar-type parameter adjustment elements may be used to ascertain and adjust one or more parameters related to one or more processes performed by the extracorporeal blood treatment systems. The bar-type parameter adjustment element may include a bar element extending from a first end representative of a lower value for an associated parameter to a second end representative of an upper value for the associated parameter, and an indicator element located along the bar element indicating the present value of the associated parameter.

An optical sensor device includes a light source configured to emit a light including a wavelength in a range of 650 to 900 nm that is exposed to a biological fluid at first and second times. At least a portion of the light is reflected off of the fluid and received by a light detector. The light detector analyzes at least a portion of the received light to determine a first intensity of the light at the wavelength at the first time and a second intensity of the light at the wavelength at the second time. A controller compares the first and second intensities and generates an output indicative of the presence of red blood cells or free hemoglobin in the biological fluid depending on which intensity is greater and whether there is more redness in the biological fluid at the first time or at the second time.

A blood component collection cassette, kit, or system, and a flow path internal pressure detection method capable of accurately measuring a circuit internal pressure. A flow path formed in a cassette body has a first line through which blood flows when a blood component separation device is in operation, and a second line through which blood does not flow when the blood component separation device is in operation. The first line has a first pressure-receiving portion pressed by a first load detector. The second line has a second pressure-receiving portion pressed by a second load detector.

An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.